The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway
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X. Coumoul | R. Barouki | C. Metayer | C. Tomkiewicz | L. Herry | L. Bui | M. Bourdeloux | Robert Barouki | L. Herry | Linh-Chi Bui | C. Métayer | M. Bourdeloux | R. Barouki
[1] A. Godwin,et al. Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death , 2012, Oncogene.
[2] O. Fardel,et al. Induction of Intracellular Calcium Concentration by Environmental Benzo(a)pyrene Involves a β2-Adrenergic Receptor/Adenylyl Cyclase/Epac-1/Inositol 1,4,5-Trisphosphate Pathway in Endothelial Cells* , 2011, The Journal of Biological Chemistry.
[3] O. Destaing,et al. Invadosome regulation by adhesion signaling. , 2011, Current opinion in cell biology.
[4] O. Fardel,et al. Aryl hydrocarbon receptor-independent up-regulation of intracellular calcium concentration by environmental polycyclic aromatic hydrocarbons in human endothelial HMEC-1 cells , 2011 .
[5] E. Golemis,et al. NEDD9 and BCAR1 Negatively Regulate E-Cadherin Membrane Localization, and Promote E-Cadherin Degradation , 2011, PloS one.
[6] J. D. De Mey,et al. FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion , 2011, Molecular biology of the cell.
[7] D. Peña,et al. Activation of c-Src/HER1/STAT5b and HER1/ERK1/2 signaling pathways and cell migration by hexachlorobenzene in MDA-MB-231 human breast cancer cell line. , 2011, Toxicological sciences : an official journal of the Society of Toxicology.
[8] Dalei Wu,et al. FRET analysis of protein tyrosine kinase c-Src activation mediated via aryl hydrocarbon receptor. , 2011, Biochimica et biophysica acta.
[9] K. Clément,et al. Fate and Complex Pathogenic Effects of Dioxins and Polychlorinated Biphenyls in Obese Subjects before and after Drastic Weight Loss , 2010, Environmental health perspectives.
[10] A. Klein-Szanto,et al. Enhanced genetic instability and dasatinib sensitivity in mammary tumor cells lacking NEDD9. , 2010, Cancer research.
[11] T. Deramaudt,et al. Hyperphosphorylated FAK Delocalizes from Focal Adhesions to Membrane Ruffles , 2010, Journal of oncology.
[12] X. Coumoul,et al. Induction of the Ras activator Son of Sevenless 1 by environmental pollutants mediates their effects on cellular proliferation. , 2010, Biochemical pharmacology.
[13] X. Coumoul,et al. 2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker agr2 in the hepatocarcinoma cell line HepG2. , 2010, Toxicological sciences : an official journal of the Society of Toxicology.
[14] D. Peña,et al. Hexachlorobenzene induces cell proliferation and IGF-I signaling pathway in an estrogen receptor alpha-dependent manner in MCF-7 breast cancer cell line. , 2010, Toxicology letters.
[15] V. Hivert,et al. Phosphorylation of human enhancer of filamentation (HEF1) on serine 369 induces its proteasomal degradation. , 2009, Biochemical pharmacology.
[16] X. Coumoul,et al. Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity , 2009, Oncogene.
[17] Paolo P. Provenzano,et al. The role of focal adhesion kinase in tumor initiation and progression , 2009, Cell adhesion & migration.
[18] D. Schlaepfer,et al. Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility. , 2009, Current opinion in cell biology.
[19] M. Wolfson,et al. NEDD9 promotes oncogenic signaling in mammary tumor development. , 2009, Cancer research.
[20] O. Destaing,et al. Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions , 2009, Journal of Cell Science.
[21] P. Fernández-Salguero,et al. Dioxin Receptor Deficiency Impairs Angiogenesis by a Mechanism Involving VEGF-A Depletion in the Endothelium and Transforming Growth Factor-β Overexpression in the Stroma* , 2009, The Journal of Biological Chemistry.
[22] P. Fernández-Salguero,et al. Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGFβ , 2009, Journal of Cell Science.
[23] S. Mulero-Navarro,et al. The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. , 2009, Molecular biology of the cell.
[24] F. Matsumura,et al. Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages. , 2009, Chemosphere.
[25] Alvaro Puga,et al. The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways. , 2009, Biochemical pharmacology.
[26] F. Matsumura. The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxin-activated Ah receptor to cause toxic effects. , 2009, Biochemical pharmacology.
[27] A. Randi,et al. Hexachlorobenzene triggers AhR translocation to the nucleus, c-Src activation and EGFR transactivation in rat liver. , 2008, Toxicology letters.
[28] G. O'Neill,et al. A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9. , 2007, Cancer research.
[29] C. Bradfield,et al. The Aryl Hydrocarbon Receptor sans Xenobiotics: Endogenous Function in Genetic Model Systems , 2007, Molecular Pharmacology.
[30] Leslie M. Tompkins,et al. Mechanisms of cytochrome P450 induction , 2007, Journal of biochemical and molecular toxicology.
[31] X. Coumoul,et al. The aryl hydrocarbon receptor, more than a xenobiotic‐interacting protein , 2007, FEBS letters.
[32] Erica A. Golemis,et al. HEF1-Dependent Aurora A Activation Induces Disassembly of the Primary Cilium , 2007, Cell.
[33] G. O'Neill,et al. Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle , 2007, Cell Biochemistry and Biophysics.
[34] L. Klotz,et al. Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation , 2007, Proceedings of the National Academy of Sciences.
[35] X. Coumoul,et al. Activation of the dioxin/aryl hydrocarbon receptor (AhR) modulates cell plasticity through a JNK-dependent mechanism , 2006, Oncogene.
[36] L. Chin,et al. Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene , 2006, Cell.
[37] Xiaoqing Chang,et al. LTBP‐1 blockade in dioxin receptor‐null mouse embryo fibroblasts decreases TGF‐β activity: Role of extracellular proteases plasmin and elastase , 2006, Journal of cellular biochemistry.
[38] Erica A. Golemis,et al. The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome , 2005, Nature Cell Biology.
[39] P. A. Pérez-Mancera,et al. Immortalized Mouse Mammary Fibroblasts Lacking Dioxin Receptor Have Impaired Tumorigenicity in a Subcutaneous Mouse Xenograft Model* , 2005, Journal of Biological Chemistry.
[40] F. Oesch,et al. TCDD induces c-jun expression via a novel Ah (dioxin) receptor-mediated p38–MAPK-dependent pathway , 2005, Oncogene.
[41] F. Oesch,et al. Evaluation of the role of c-Src and ERK in TCDD-dependent release from contact-inhibition in WB-F344 cells , 2005, Archives of Toxicology.
[42] R. Barouki,et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin Induces Insulin-Like Growth Factor Binding Protein-1 Gene Expression and Counteracts the Negative Effect of Insulin , 2005, Molecular Pharmacology.
[43] T. Takeuchi,et al. Protein kinase Cθ activity is involved in the 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin‐induced signal transduction pathway leading to apoptosis in L‐MAT, a human lymphoblastic T‐cell line , 2005 .
[44] N. Ledirac,et al. The role of protein tyrosine kinases in CYP1A1 induction by omeprazole and thiabendazole in rat hepatocytes. , 2004, Life sciences.
[45] F. Matsumura,et al. The use of c‐src knockout mice for the identification of the main toxic signaling pathway of TCDD to Induce wasting syndrome , 2003, Journal of biochemical and molecular toxicology.
[46] M. Denison,et al. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. , 2003, Annual review of pharmacology and toxicology.
[47] G. Perdew,et al. The role of chaperone proteins in the aryl hydrocarbon receptor core complex. , 2002, Chemico-biological interactions.
[48] P. Brown,et al. Use of cDNA microarrays to analyze dioxin-induced changes in human liver gene expression. , 2001, Toxicology letters.
[49] M. Medvedovic,et al. The transcriptional signature of dioxin in human hepatoma HepG2 cells. , 2000, Biochemical pharmacology.
[50] G. O'Neill,et al. Integrin signalling: a new Cas(t) of characters enters the stage. , 2000, Trends in cell biology.
[51] H. Gschaidmeier,et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-mediated membrane translocation of c-Src protein kinase in liver WB-F344 cells , 1999, Archives of Toxicology.
[52] W B Wood,et al. Caenorhabditis elegans orthologs of the aryl hydrocarbon receptor and its heterodimerization partner the aryl hydrocarbon receptor nuclear translocator. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[53] Kenji Nakamura,et al. Loss of teratogenic response to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) in mice lacking the Ah (dioxin) receptor , 1997, Genes to cells : devoted to molecular & cellular mechanisms.
[54] F. Matsumura,et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced activation of a protein tyrosine kinase, pp60src, in murine hepatic cytosol using a cell-free system. , 1997, Molecular pharmacology.
[55] F. Matsumura,et al. Identification of c-Src as the integral component of the cytosolic Ah receptor complex, transducing the signal of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through the protein phosphorylation pathway. , 1996, Biochemical pharmacology.
[56] E. Golemis,et al. Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae , 1996, Molecular and cellular biology.
[57] J. Reddy,et al. Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[58] T. Pineau,et al. Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor , 1995, Science.
[59] S. Hanks,et al. Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases , 1995, Molecular and cellular biology.
[60] S. J. Taylor,et al. Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain. , 1994, Molecular biology of the cell.
[61] J. Parsons,et al. Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK , 1993, Molecular and cellular biology.
[62] T. Deramaudt,et al. Src activation and translocation from focal adhesions to membrane ruffles contribute to formation of new adhesion sites , 2008, Cellular and Molecular Life Sciences.
[63] H. Ashida,et al. An update on the dietary ligands of the AhR. , 2008, Expert opinion on drug metabolism & toxicology.
[64] T. Takeuchi,et al. Protein kinase Ctheta activity is involved in the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line. , 2005, The FEBS journal.
[65] M. Ingelman-Sundberg,et al. Regulation of aryl hydrocarbon receptor signal transduction by protein tyrosine kinases. , 2005, Cellular signalling.
[66] F. Matsumura,et al. Use of c‐Src and c‐Fos knockout mice for the studies on the role of c‐Src kinase signaling in the expression of toxicity of TCDD , 1998, Journal of biochemical and molecular toxicology.