The impact of apheresis platelet manipulation on corrected count increment

BACKGROUND: Concentrating and washing apheresis platelets (APs) substantially reduce the number of allergic transfusion reactions likely due to removal of plasma. However, these processes may damage platelets (PLTs). This study evaluated whether concentrating or washing APs decrease the corrected count increment (CCI).

[1]  J. Schroeder,et al.  Allergic agonists in apheresis platelet products are associated with allergic transfusion reactions , 2012, Transfusion.

[2]  A. Tobian,et al.  Atopic predisposition of recipients in allergic transfusion reactions to apheresis platelets , 2011, Transfusion.

[3]  A. Tobian,et al.  Prevention of allergic transfusion reactions to platelets and red blood cells through plasma reduction , 2011, Transfusion.

[4]  R. Wood,et al.  Allergic transfusion reactions to platelets are associated more with recipient and donor factors than with product attributes , 2011, Transfusion.

[5]  J. Bornhorst,et al.  A comparison of washed and volume‐reduced platelets with respect to platelet activation, aggregation, and plasma protein removal , 2011, Transfusion.

[6]  Jeffrey McCullough,et al.  Dose of prophylactic platelet transfusions and prevention of hemorrhage. , 2010, The New England journal of medicine.

[7]  C. Homma,et al.  Reduction in adverse reactions to platelets by the removal of plasma supernatant and resuspension in a new additive solution (M‐sol) , 2009, Transfusion.

[8]  A. Tobian,et al.  Transfusion premedications: a growing practice not based on evidence , 2007, Transfusion.

[9]  R. Brand,et al.  A multicenter randomized study of the efficacy of transfusions with platelets stored in platelet additive solution II versus plasma. , 2006, Blood.

[10]  C. Spies,et al.  Volume-reduced platelet concentrates. , 2006, Current hematology reports.

[11]  M. Salama,et al.  Platelet function testing to assess effectiveness of platelet transfusion therapy. , 2004, Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.

[12]  S. Slichter,et al.  Factors influencing moderate to severe reactions to PLT transfusions: experience of the TRAP multicenter clinical trial , 2003, Transfusion.

[13]  G. Hoeltge,et al.  Allergic transfusion reactions: an evaluation of 273 consecutive reactions. , 2003, Archives of pathology & laboratory medicine.

[14]  Laurence Klotz.  Reactions , 2002, The Lancet.

[15]  P. Ness,et al.  Efficacy of washed platelets for the treatment of severe allergic transfusion reactions , 2001 .

[16]  M. Bins,et al.  Reactions and platelet increments after transfusion of platelet concentrates in plasma or an additive solution: a prospective, randomized study , 2000, Transfusion.

[17]  L. Corash,et al.  Corrected count increment and percent platelet recovery as measures of posttransfusion platelet response: problems and a solution , 1999, Transfusion.

[18]  H. Braine,et al.  The utility of platelet washing using an automated procedure for severe platelet allergic reactions , 1987, Transfusion.

[19]  N. Luban,et al.  Reduction of the volume of stored platelet concentrates for use in neonatal patients , 1984, Transfusion.

[20]  F. Grumet,et al.  Clinical Value of Washed‐Platelet Concentrates in Patients with Non‐Hemolytic Transfusion Reactions , 1977, Transfusion.

[21]  S. Garza Salinas,et al.  [Prevention of allergic diseases]. , 1969, Alergia.