Combination of preoperative irradiation and surgery in the treatment of cancer of the oropharynx, hypopharynx, and larynx

Sixty‐eight patients with carcinoma of the oropharynx, hypopharynx, and larynx were treated with combinations of preoperative irradiation and surgery. Fifty‐six had low‐dose preoperative irradiation, and 12 had high‐dose preoperative irradiation. This report evaluates the 2‐year survival, morbidity, wound healing, and local recurrence in relation to the type of surgery and to radiation dose and timing in these groups where applicable. These findings are compared to those in a similar group of 29 patients receiving surgery alone.

[1]  H. Biller,et al.  Planned pre‐operative irradiation for carcinoma of the larynx and laryngopharynx treated by total and partial laryngectomy. , 1969, The Laryngoscope.

[2]  H. Biller,et al.  Surgical treatment of carcinoma of the larynx, pharynx, base of tongue and cervical esophagus. , 1969, International surgery.

[3]  E. Strong.  Preoperative radiation and radical neck dissection. , 1969, The Surgical clinics of North America.

[4]  F. W. Parnell.  Complications of radical neck dissection. , 1968, Archives of otolaryngology.

[5]  F. Hendrickson,et al.  XXIII Results of Pre-Operative Radiotherapy for Supraglottic Larynx Cancer , 1968, The Annals of otology, rhinology, and laryngology.

[6]  W. S. Maccomb.  Mortality from radical neck dissection , 1968 .

[7]  K. Sako,et al.  Complications after radical head and neck surgery performed through previously irradiated tissues. , 1967, American journal of surgery.

[8]  C. Perez,et al.  Studies on optimal dose of preoperative irradiation and time for surgery in the cure of a mouse lymphosarcoma. , 1967, Radiology.

[9]  F. Zak,et al.  XXV Histopathology of Larynges and Radical Neck Specimens , 1966 .

[10]  E. Strong,et al.  Value of preoperative x-ray therapy as an adjunct to radical neck dissection. , 1966, Radiology.

[11]  J. Ogura,et al.  PREOPERATIVE IRRADIATION IN HEAD AND NECK CANCER SURGERY. , 1965, Archives of otolaryngology.

[12]  F. Zak,et al.  Combined radiation and surgical therapy for cancer of the larynx and laryngopharynx ii , 1964, Transactions of the American Laryngological, Rhinological and Otological Society, Inc.

[13]  W. Schlosser.  A clinical investigation of the surgical treatment of congenital mixed deafness , 1964, The Laryngoscope.

[14]  G. Fletcher,et al.  The contribution of supervoltage roentgenotherapy to the integration of radiation and surgery in head and neck squamous cell carcinomas , 1962, Cancer.

[15]  M. Galante,et al.  Radical preoperative roentgen therapy in primarily inoperable advanced cancers of the head and neck. , 1959, Radiology.

[16]  Fletcher Gh,et al.  Planned combination of surgery and radiation in treatment of advanced primary head and neck cancers. , 1957 .