Retrospective Evaluation of Hemithyroidectomy in 14 Horses.

OBJECTIVE To describe the presentation, presurgical diagnostic findings, treatment, and outcome of horses with histologically confirmed, unilateral thyroid neoplasia. The complications, particularly laryngeal hemiplegia, were investigated. STUDY DESIGN Retrospective case series. ANIMALS Client-owned horses (n=14). METHODS Medical records of horses presenting with a unilateral thyroid mass due to neoplasia from 2003-2015 were reviewed. Horses must have undergone preoperative clinical evaluations that included ultrasound examination of the mass and upper airway endoscopy. Short-term follow-up at 2 weeks after surgery and owner questionnaire for long-term follow-up at >6 months were completed. RESULTS Fourteen horses aged 6-21 years were included. The majority of tumors were adenocarcinomas (11/14), mainly diagnosed in mares (9/14). Intraoperative complications included hemorrhage (1/14) and postoperative complications included seroma formation (4/14). No horse developed postoperative laryngeal hemiplegia. No horses developed clinical signs of metastases or a thyroid disorder long term (mean follow-up 4.9 years). All owners reported a successful long-term outcome. CONCLUSION The clinical findings of thyroid neoplasia in horses are not associated with the diagnosis of malignancy. Complete surgical resection of the abnormal lobe prevents local recurrence of neoplastic thyroid tissue. The modified hemithyroidectomy technique preserves the function of the recurrent laryngeal nerve.

[1]  L. Rubio‐Martínez,et al.  The use of nuclear imaging for a mixed C cell microfollicular carcinoma of the thyroid gland in a mature horse , 2013 .

[2]  C. Timon,et al.  Changing trends in thyroidectomy. , 2012, Irish medical journal.

[3]  Yang Zhang,et al.  Prognostic factors for differentiated thyroid carcinoma and review of the literature. , 2012, Tumori.

[4]  R. Pirie,et al.  Thyroid carcinoma with multiple metastases in a horse , 2010 .

[5]  A. Kappe,et al.  Unilateral thyroidectomy in 5 horses with thyroid tumors. , 2009 .

[6]  S. Shi,et al.  Chapter 1 – Techniques of Immunohistochemistry: Principles, Pitfalls and Standardization , 2006 .

[7]  T. Oyamada,et al.  Non-functional C-cell adenoma in aged horses. , 2004, Journal of comparative pathology.

[8]  A. O. Ceribasi,et al.  Equine goiter associated with excess dietary iodine. , 2004, Veterinary and human toxicology.

[9]  M. Ross,et al.  Unilateral thyroidectomy in 6 horses. , 2003, Veterinary surgery : VS.

[10]  P. R. Woods,et al.  Hemithyroidectomy in a horse with confirmed hyperthyroidism. , 2000, Journal of the American Veterinary Medical Association.

[11]  K. Wolfsheimer,et al.  Hyperthyroidism associated with a thyroid adenocarcinoma in a 21-year-old gelding. , 1998, Journal of veterinary internal medicine.

[12]  J. Yamate,et al.  C-cell adenoma containing variously sized thyroid follicles in a horse. , 1998, The Journal of veterinary medical science.

[13]  S. Ichijo,et al.  Clinicopathological observations on thoroughbred foals with enlarged thyroid gland. , 1994, The Journal of veterinary medical science.

[14]  R. Dalefield,et al.  The frequent occurrence of thyroid tumours in aged horses. , 1994, Journal of comparative pathology.

[15]  K. Okada,et al.  A case of equine thyroid follicular carcinoma accompanied with adenohypophysial adenoma. , 1987, Nihon juigaku zasshi. The Japanese journal of veterinary science.

[16]  H. Meulenaar,et al.  Medullary Thyroid Carcinoma in a Horse , 1986, Veterinary pathology.

[17]  V. Lucke,et al.  C-cell tumours of the thyroid in the horse. , 1984, Equine veterinary journal.

[18]  J. Turk,et al.  Ultimobranchial Adenoma of the Thyroid Gland in a Horse , 1983, Veterinary pathology.

[19]  R. Sanecki,et al.  Thyroid carcinoma in a horse. , 1982, Journal of the American Veterinary Medical Association.

[20]  R. Straub,et al.  [Thyroid carcinoma with bone metastases in the horse]. , 1979, Schweizer Archiv fur Tierheilkunde.

[21]  Malecki Jc Radioimmunoassay of equine serum for thyroxine: reference values (a selected report) , 1978 .

[22]  J. R. Kyzar,et al.  Thyroid carcinoma in a horse. , 1976, Journal of the American Veterinary Medical Association.