Histamine Augments Leukocyte Adenosine 3',5'-Monophosphate and Blocks Antigenic Histamine Release

Extracellular histamine stimulates accumulation of adenosine 3',5'-monophosphate in human leukocytes and prevents antigenic release of histamine from cells of allergic donors. Both effects occur at histamine concentrations that can be achieved by antigenic release of the amine in vitro.

[1]  K. Austen,et al.  Immunochemical and biologic properties of rat IgE. 3. Modulation of the IgE-mediated release of slow-reacting substance of anaphylaxis by agents influencing the level of cyclic 3',5'-adenosine monoposphate. , 1970, Journal of immunology.

[2]  L. Lichtenstein,et al.  In vitro reversed anaphylaxis: characteristics of anti-IgE mediated histamine release. , 1970, Immunology.

[3]  E. Assem,et al.  Inhibition by Sympathomimetic Amines of Histamine Release induced by Antigen in Passively Sensitized Human Lung , 1969, Nature.

[4]  J. Daly,et al.  A RADIOISOTOPIC METHOD FOR MEASURING THE FORMATION OF ADENOSINE 3′,5′‐CYCLIC MONOPHOSPHATE IN INCUBATED SLICES OF BRAIN , 1969, Journal of neurochemistry.

[5]  P. A. Tavormina,et al.  Platelet aggregation. I. Regulation by cyclic AMP and prostaglandin E1. , 1969, Biochemical and biophysical research communications.

[6]  B B Brodie,et al.  A simple, sensitive method for the assay of adenyl cyclase. , 1968, The Journal of pharmacology and experimental therapeutics.

[7]  J. Franchina,et al.  Strychnine and the Inhibition of Previous Performance , 1968, Science.

[8]  R. Butcher,et al.  Some Aspects of the Biological Role of Adenosine 3′,5′‐monophosphate (Cyclic AMP) , 1968 .

[9]  A. G. Osler,et al.  In vitro studies of human ragweed allergy: changes in cellular and humoral activity associated with specific desensitization. , 1966, The Journal of clinical investigation.

[10]  A. G. Osler,et al.  STUDIES ON THE MECHANISMS OF HYPERSENSITIVITY PHENOMENA. IX. HISTAMINE RELEASE FROM HUMAN LEUKOCYTES BY RAGWEED POLLEN ANTIGEN. , 1964 .