TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.
暂无分享,去创建一个
J. Issa | J. Jelinek | M. Estecio | H. Kantarjian | S. Liang | M. Cesaroni | Yue Lu | L. Godley | A. Vasanthakumar | J. Madzo | F. Neumann | Trisha A. Macrae | R. He | J. Yamazaki | K. R. Ostler | Rodolphe Taby | S. Liang | Kelly R. Ostler
[1] Lee E. Edsall,et al. 5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation. , 2014, Molecular cell.
[2] Yi Zhang,et al. Role of Tet proteins in enhancer activity and telomere elongation , 2014, Genes & development.
[3] Daniel R. Zerbino,et al. Ensembl 2014 , 2013, Nucleic Acids Res..
[4] C. Hother,et al. Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma , 2013, Haematologica.
[5] J. Issa,et al. Conserved DNA methylation patterns in healthy blood cells and extensive changes in leukemia measured by a new quantitative technique , 2012, Epigenetics.
[6] Mithat Gonen,et al. Recurrent Somatic TET2 Mutations in Normal Elderly Individuals With Clonal Hematopoiesis , 2012, Nature Genetics.
[7] Raymond K. Auerbach,et al. An Integrated Encyclopedia of DNA Elements in the Human Genome , 2012, Nature.
[8] G. Hon,et al. Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome , 2012, Cell.
[9] J. Cigudosa,et al. TET2 Mutations Are Associated with Specific 5-Methylcytosine and 5-Hydroxymethylcytosine Profiles in Patients with Chronic Myelomonocytic Leukemia , 2012, PloS one.
[10] J. Issa,et al. Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia , 2012, Epigenetics.
[11] K. Helin,et al. DNA methylation: TET proteins—guardians of CpG islands? , 2012, EMBO reports.
[12] Vijay K. Tiwari,et al. DNA-binding factors shape the mouse methylome at distal regulatory regions , 2011, Nature.
[13] J. Berg,et al. Dnmt3a is essential for hematopoietic stem cell differentiation , 2011, Nature Genetics.
[14] A. Vekhoff,et al. Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial. , 2011, Blood.
[15] Chuan He,et al. Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine , 2011, Science.
[16] Yang Wang,et al. Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA , 2011, Science.
[17] O. Abdel-Wahab,et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. , 2011, Cancer cell.
[18] P. Opolon,et al. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. , 2011, Cancer cell.
[19] Suhua Feng,et al. 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells , 2011, Genome Biology.
[20] Juri Rappsilber,et al. TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity , 2011, Nature.
[21] W. Reik,et al. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation , 2011, Nature.
[22] J. Licht,et al. DNMT3A mutations in acute myeloid leukemia , 2011, Nature Genetics.
[23] Keji Zhao,et al. Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells , 2011, Nature.
[24] Li Ding,et al. Recurrent DNMT3A Mutations in Patients with Myelodysplastic Syndromes , 2011, Leukemia.
[25] P. Jin,et al. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine , 2011, Nature Biotechnology.
[26] J. Licht,et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. , 2010, Cancer cell.
[27] L. Aravind,et al. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2 , 2010, Nature.
[28] Yi Zhang,et al. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification , 2010, Nature.
[29] D. Birnbaum,et al. Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms , 2010, Leukemia.
[30] D. Berry,et al. DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[31] J. Soulier,et al. Mutation in TET2 in myeloid cancers. , 2009, The New England journal of medicine.
[32] D. Birnbaum,et al. TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia , 2009, Haematologica.
[33] D. Gilliland,et al. Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. , 2009, Blood.
[34] A. Hagemeijer,et al. Acquired mutations in TET2 are common in myelodysplastic syndromes , 2009, Nature Genetics.
[35] Jungwon Huh,et al. Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms. , 2009, Blood.
[36] D. Gilliland,et al. Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML , 2009, Leukemia.
[37] S. Henikoff,et al. Predicting the effects of amino acid substitutions on protein function. , 2006, Annual review of genomics and human genetics.
[38] John M Bennett,et al. Decitabine improves patient outcomes in myelodysplastic syndromes , 2006, Cancer.
[39] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[40] Toshihiro Tanaka. The International HapMap Project , 2003, Nature.
[41] K A Baggerly,et al. Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites. , 2003, BioTechniques.
[42] R. Goodman,et al. CREB-binding Protein and p300 in Transcriptional Regulation* , 2001, The Journal of Biological Chemistry.
[43] M. Frommer,et al. CpG islands in vertebrate genomes. , 1987, Journal of molecular biology.
[44] Kairong Cui,et al. Dual functions of Tet 1 in transcriptional regulation in mouse embryonic stem cells , 2011 .
[45] David R. Liu,et al. Conversion of 5-Methylcytosine to 5- Hydroxymethylcytosine in Mammalian DNA by the MLL Partner TET1 , 2009 .
[46] D. Gilliland,et al. Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates , 2009, Leukemia.
[47] F. Ducray,et al. IDH1 and IDH2 mutations in gliomas. , 2009, The New England journal of medicine.