miRNA-205: a future therapeutic molecule for liver diseases

study results suggest that miR-205 / NEU1 can be a viable therapeutic target for treatment of NAFLD. In the series of experiments conducted on mouse models, it was found that miR-205 has an effect on transcription factor ZEBI, which has a role in liver metabolism and insulin resistance [20] . On the other hand, when NZ10 mice were predisposed with obesity, Type 2 diabetes and hepatic steatosis; fed with high protein fish oil diet and examined for the biochemical and physical functions, results showed that the diet prevented steatosis and reduced serum cholesterol and triglycerides

[1]  G. Jemec,et al.  Methylated miRNAs may serve as potential biomarkers and therapeutic targets for hidradenitis suppurativa , 2022, Journal of the European Academy of Dermatology and Venereology : JEADV.

[2]  M. Khairy,et al.  Highly Sensitive Serum miRNA Panel for the Diagnosis of Hepatocellular Carcinoma in Egyptian Patients with HCV-Related HCC. , 2022, Laboratoriums Medizin.

[3]  X. Ren,et al.  DNAJA1 Stabilizes EF1A1 to Promote Cell Proliferation and Metastasis of Liver Cancer Mediated by miR-205-5p , 2022, Journal of oncology.

[4]  A. Czaja.  Examining micro-ribonucleic acids as diagnostic and therapeutic prospects in autoimmune hepatitis , 2022, Expert review of clinical immunology.

[5]  Fei Li,et al.  LncRNA MIR205HG accelerates cell proliferation, migration and invasion in hepatoblastoma through the activation of MAPK signaling pathway and PI3K/AKT signaling pathway , 2022, Biology direct.

[6]  Yong Ji,et al.  Bone marrow mesenchymal stem cells-secreted exosomal microRNA-205-5p exerts inhibitory effect on the progression of liver cancer through regulating CDKL3. , 2021, Pathology, research and practice.

[7]  N. Chauhan,et al.  miR-205: A Potential Biomedicine for Cancer Therapy , 2020, Cells.

[8]  R. Yaghobi,et al.  Importance of miR-125a-5p and miR-122-5p expression in patients with HBV infection. , 2020, Cellular and molecular biology.

[9]  H. Ye,et al.  MicroRNA-205 ameliorates lipid accumulation in non-alcoholic fatty liver disease through targeting NEU1. , 2019, European review for medical and pharmacological sciences.

[10]  C. Kahn,et al.  Identification of two microRNA nodes as potential cooperative modulators of liver metabolism , 2019, Hepatology research : the official journal of the Japan Society of Hepatology.

[11]  Shuyan Liu,et al.  Upregulation of miR-205 induces CHN1 expression, which is associated with the aggressive behaviour of cervical cancer cells and correlated with lymph node metastasis , 2019, BMC cancer.

[12]  P. Kamath,et al.  Burden of liver diseases in the world. , 2019, Journal of hepatology.

[13]  B. Yang,et al.  [Long non-coding RNA HULC affects downstream-related targets to regulate migration and invasion of hepatoma cells]. , 2018, Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology.

[14]  Olaf Wolkenhauer,et al.  MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance , 2018, Theranostics.

[15]  Long-Bang Chen,et al.  Hepatitis B virus X protein-mediated non-coding RNA aberrations in the development of human hepatocellular carcinoma , 2017, Experimental &Molecular Medicine.

[16]  L. Henry,et al.  Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes , 2016, Hepatology.

[17]  K. Webster,et al.  High protein/fish oil diet prevents hepatic steatosis in NONcNZO10 mice; association with diet/genetics-regulated micro-RNAs. , 2016, Journal of diabetes & metabolism.

[18]  Jian-hua Wang,et al.  MicroRNA-205 regulates ubiquitin specific peptidase 7 protein expression in hepatocellular carcinoma cells. , 2015, Molecular medicine reports.

[19]  R. Chakravarty,et al.  Hepatitis B Virus Infection, MicroRNAs and Liver Disease , 2015, International journal of molecular sciences.

[20]  R. Mahato,et al.  Efficacy of gemcitabine conjugated and miRNA-205 complexed micelles for treatment of advanced pancreatic cancer. , 2014, Biomaterials.

[21]  Yue Wang,et al.  Involvement of cholesterol in hepatitis B virus X protein-induced abnormal lipid metabolism of hepatoma cells via up-regulating miR-205-targeted ACSL4. , 2014, Biochemical and biophysical research communications.

[22]  Lihong Ye,et al.  MiR-205 modulates abnormal lipid metabolism of hepatoma cells via targeting acyl-CoA synthetase long-chain family member 1 (ACSL1) mRNA. , 2014, Biochemical and biophysical research communications.

[23]  Yumei Du,et al.  Hepatitis B virus X protein inhibits tumor suppressor miR-205 through inducing hypermethylation of miR-205 promoter to enhance carcinogenesis. , 2013, Neoplasia.

[24]  G. Gonye,et al.  Chronic ethanol feeding enhances miR-21 induction during liver regeneration while inhibiting proliferation in rats. , 2012, American journal of physiology. Gastrointestinal and liver physiology.

[25]  N. Davidson,et al.  MicroRNAs and liver disease. , 2011, Translational research : the journal of laboratory and clinical medicine.

[26]  Qin-Hui Tuo,et al.  CHANGES IN microRNA (miR) PROFILE AND EFFECTS OF miR‐320 IN INSULIN‐RESISTANT 3T3‐L1 ADIPOCYTES , 2009, Clinical and experimental pharmacology & physiology.

[27]  G. Goodall,et al.  The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 , 2008, Nature Cell Biology.

[28]  Aibin He,et al.  Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes. , 2007, Molecular endocrinology.

[29]  D. Bartel.  MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.

[30]  OUP accepted manuscript , 2022, Laboratoriums Medizin.

[31]  J. Zhao,et al.  Down-regulation of miR-205 promotes stemness of hepatocellular carcinoma cells by targeting PLCβ1 and increasing CD24 expression. , 2015, Neoplasma.