Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group

[1]  G. Iliakis,et al.  Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants , 2000, Oncogene.

[2]  J. Albala,et al.  The Rad51 Paralog Rad51B Promotes Homologous Recombinational Repair , 2000, Molecular and Cellular Biology.

[3]  J. Hoeijmakers,et al.  Mouse RAD54 Affects DNA Double-Strand Break Repair and Sister Chromatid Exchange , 2000, Molecular and Cellular Biology.

[4]  J. Hoeijmakers,et al.  Homologous and non‐homologous recombination differentially affect DNA damage repair in mice , 2000, The EMBO journal.

[5]  T Hyslop,et al.  DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus. , 2000, Cancer research.

[6]  L. Thompson,et al.  XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. , 1999, Genes & development.

[7]  J. Haber DNA recombination: the replication connection. , 1999, Trends in biochemical sciences.

[8]  P. Jeggo,et al.  Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient , 1999, Current Biology.

[9]  J. Thacker A surfeit of RAD51-like genes? , 1999, Trends in genetics : TIG.

[10]  C. Ling,et al.  Rejoining of DNA double-strand breaks in Ku80-deficient mouse fibroblasts. , 1999, Radiation research.

[11]  D. Schild,et al.  The contribution of homologous recombination in preserving genome integrity in mammalian cells. , 1999, Biochimie.

[12]  L. Peng,et al.  Analysis of the human RAD51L1 promoter region and its activation by UV light. , 1998, Genomics.

[13]  J. Hoeijmakers,et al.  Molecular mechanisms of DNA double strand break repair. , 1998, Trends in cell biology.

[14]  Akira Shinohara,et al.  Homologous Recombination, but Not DNA Repair, Is Reduced in Vertebrate Cells Deficient in RAD52 , 1998, Molecular and Cellular Biology.

[15]  B. Morolli,et al.  Targeted Inactivation of Mouse RAD52Reduces Homologous Recombination but Not Resistance to Ionizing Radiation , 1998, Molecular and Cellular Biology.

[16]  K. Schwarz,et al.  DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes. , 1998, Molecular cell.

[17]  M. Lieber,et al.  Requirement for an Interaction of XRCC4 with DNA Ligase IV for Wild-type V(D)J Recombination and DNA Double-strand Break Repairin Vivo * , 1998, The Journal of Biological Chemistry.

[18]  Y. Yamaguchi-Iwai,et al.  Homologous recombination and non‐homologous end‐joining pathways of DNA double‐strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells , 1998, The EMBO journal.

[19]  P. Baumann,et al.  Role of the human RAD51 protein in homologous recombination and double-stranded-break repair. , 1998, Trends in biochemical sciences.

[20]  J. Haycock,et al.  A DEVD‐Inhibited Caspase Other than CPP32 Is Involved in the Commitment of Cerebellar Granule Neurons to Apoptosis Induced by K+ Deprivation , 1998, Journal of neurochemistry.

[21]  J. Lamerdin,et al.  XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. , 1998, Molecular cell.

[22]  M. Jasin,et al.  Homology-directed repair is a major double-strand break repair pathway in mammalian cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[23]  M. Resnick,et al.  Requirement for End-Joining and Checkpoint Functions, but NotRAD52-Mediated Recombination, after EcoRI Endonuclease Cleavage of Saccharomyces cerevisiaeDNA , 1998, Molecular and Cellular Biology.

[24]  W. Dynan,et al.  Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids. , 1998, Nucleic acids research.

[25]  S. Jackson,et al.  Components of the Ku‐dependent non‐homologous end‐joining pathway are involved in telomeric length maintenance and telomeric silencing , 1998, The EMBO journal.

[26]  P. Baumann,et al.  Synergistic actions of Rad51 and Rad52 in recombination and DNA repair , 1998, Nature.

[27]  A. Shinohara,et al.  Stimulation by Rad52 of yeast Rad51- mediated recombination , 1998, Nature.

[28]  S. Kowalczykowski,et al.  Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A , 1998, Nature.

[29]  S. Jackson,et al.  The DNA-dependent protein kinase , 1999 .

[30]  P. Sung Function of Yeast Rad52 Protein as a Mediator between Replication Protein A and the Rad51 Recombinase* , 1997, The Journal of Biological Chemistry.

[31]  J. Nickoloff,et al.  Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells , 1997, Molecular and cellular biology.

[32]  David J. Chen,et al.  Ku70 Is Required for DNA Repair but Not for T Cell Antigen Receptor Gene Recombination In Vivo , 1997, The Journal of experimental medicine.

[33]  S. Jackson,et al.  Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double‐strand break repair , 1997, The EMBO journal.

[34]  F. Bullrich,et al.  Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[35]  J. Petrini,et al.  TheRAD52epistasis group in mammalian double strand break repair , 1997 .

[36]  M. Resnick,et al.  A persistent double-strand break destabilizes human DNA in yeast and can lead to G2 arrest and lethality. , 1997, Cancer research.

[37]  B. Nevaldine,et al.  The scid defect results in much slower repair of DNA double-strand breaks but not high levels of residual breaks. , 1997, Radiation research.

[38]  Yuko Yamaguchi-Iwai,et al.  Reduced X-Ray Resistance and Homologous Recombination Frequencies in a RAD54−/− Mutant of the Chicken DT40 Cell Line , 1997, Cell.

[39]  J. Hoeijmakers,et al.  Disruption of Mouse RAD54 Reduces Ionizing Radiation Resistance and Homologous Recombination , 1997, Cell.

[40]  M. Lieber,et al.  Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks. , 1997, Current opinion in genetics & development.

[41]  M. Brenneman,et al.  Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination , 1997, Molecular and cellular biology.

[42]  S. Jackson,et al.  Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. , 1996, Nucleic acids research.

[43]  P. Hasty,et al.  A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53 , 1996, Molecular and cellular biology.

[44]  C. Bendixen,et al.  DNA strand annealing is promoted by the yeast Rad52 protein. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[45]  S. Boulton,et al.  Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double‐strand break repair and serves as a barrier to error‐prone DNA repair pathways. , 1996, The EMBO journal.

[46]  M. Resnick,et al.  A double-strand break within a yeast artificial chromosome (YAC) containing human DNA can result in YAC loss, deletion or cell lethality , 1996, Molecular and cellular biology.

[47]  K. Nakao,et al.  Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[48]  T. Kogoma Recombination by Replication , 1996, Cell.

[49]  D. Weaver,et al.  Regulation and repair of double-strand DNA breaks. , 1996, Critical reviews in eukaryotic gene expression.

[50]  J. Brown,et al.  Induction and repair of chromosome aberrations in scid cells measured by premature chromosome condensation. , 1996, Radiation research.

[51]  M. Löbrich,et al.  Repair of x-ray-induced DNA double-strand breaks in specific Not I restriction fragments in human fibroblasts: joining of correct and incorrect ends. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[52]  P. Jeggo,et al.  DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. , 1995, Trends in biochemical sciences.

[53]  A. Shinohara,et al.  Homologous recombination and the roles of double-strand breaks. , 1995, Trends in biochemical sciences.

[54]  C. Badie,et al.  Induction and rejoining of DNA double-strand breaks and interphase chromosome breaks after exposure to X rays in one normal and two hypersensitive human fibroblast cell lines. , 1995, Radiation research.

[55]  B. Dujon,et al.  Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae , 1995, Molecular and cellular biology.

[56]  D. Weaver V(D)J recombination and double-strand break repair. , 1995, Advances in immunology.

[57]  P. Rouet,et al.  Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. , 1994, Molecular and cellular biology.

[58]  S. Lovett Sequence of the RAD55 gene of Saccharomyces cerevisiae: similarity of RAD55 to prokaryotic RecA and other RecA-like proteins. , 1994, Gene.

[59]  R. Okayasu,et al.  Evidence that the product of the xrs gene is predominantly involved in the repair of a subset of radiation-induced interphase chromosome breaks rejoining with fast kinetics. , 1994, Radiation research.

[60]  X. Wang,et al.  Loss of S-phase-dependent radioresistance in irs-1 cells exposed to X-rays. , 1994, Mutation research.

[61]  D. Frankenberg,et al.  Half-life values for DNA double-strand break rejoining in yeast can vary by more than an order of magnitude depending on the irradiation conditions. , 1994, International journal of radiation biology.

[62]  J. Buerstedde,et al.  Identification of a chicken RAD52 homologue suggests conservation of the RAD52 recombination pathway throughout the evolution of higher eukaryotes. , 1993, Nucleic acids research.

[63]  K. Ikeo,et al.  Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA , 1993, Nature Genetics.

[64]  G. Iliakis,et al.  Radiation-sensitive irs mutants rejoin DNA double-strand breaks with efficiency similar to that of parental V79 cells but show altered response to radiation-induced G2 delay. , 1992, Mutation research.

[65]  R. Chanet,et al.  Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins , 1992, Molecular and cellular biology.

[66]  R. Mortimer,et al.  Nucleotide sequence and transcriptional regulation of the yeast recombinational repair gene RAD51 , 1992, Molecular and Cellular Biology.

[67]  J. Haber Exploring the pathways of homologous recombination , 1992, Current Biology.

[68]  N. Kleckner,et al.  DMC1: A meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression , 1992, Cell.

[69]  A. Shinohara,et al.  Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein , 1992, Cell.

[70]  G. Iliakis,et al.  Level of DNA double-strand break rejoining in Chinese hamster xrs-5 cells is dose-dependent: implications for the mechanism of radiosensitivity. , 1992, International journal of radiation biology.

[71]  George Lliakis,et al.  The role of DNA double strand breaks in lonizing radiation‐induced killing of eukaryotic cells , 1991 .

[72]  Jean-Marie Buerstedde,et al.  Increased ratio of targeted to random integration after transfection of chicken B cell lines , 1991, Cell.

[73]  G. Iliakis,et al.  Kinetics of DNA double-strand break repair throughout the cell cycle as assayed by pulsed field gel electrophoresis in CHO cells. , 1991, International journal of radiation biology.

[74]  D. Schatz,et al.  A link between double-strand break-related repair and V(D)J recombination: the scid mutation. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[75]  G. Iliakis,et al.  Measurement of DNA double-strand breaks in CHO cells at various stages of the cell cycle using pulsed field gel electrophoresis: calibration by means of 125I decay. , 1991, International journal of radiation biology.

[76]  G. Iliakis,et al.  Detection of DNA double-strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis. , 1991, International journal of radiation biology.

[77]  J. Thacker,et al.  DNA-break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: comparisons to ataxia-telangiectasia cells. , 1990, Mutation research.

[78]  J. Maio,et al.  DNA base and strand damage in X-irradiated monkey CV-1 cells: influence of pretreatment using small doses of radiation. , 1990, International journal of radiation biology.

[79]  M. Frankenberg-Schwager Induction, repair and biological relevance of radiation-induced DNA lesions in eukaryotic cells , 1990, Radiation and environmental biophysics.

[80]  L. Thompson,et al.  Biochemical and genetic analysis of the Chinese hamster mutants irs1 and irs2 and their comparison to cultured ataxia telangiectasia cells. , 1990, Mutagenesis.

[81]  M. Frankenberg-Schwager Review of repair kinetics for DNA damage induced in eukaryotic cells in vitro by ionizing radiation. , 1989, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[82]  R. Painter,et al.  A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication. , 1988, Mutation research.

[83]  R. Mortimer,et al.  Analysis of DNA double strand breakage and repair using orthogonal field alternation gel electrophoresis , 1987, Yeast.

[84]  E. Dikomey,et al.  Three classes of DNA strand breaks induced by X-irradiation and internal β-rays , 1986 .

[85]  J. Maio,et al.  X-ray-induced base sequence damage in primate alphoid DNA. , 1986, Radiation research.

[86]  J. Ward,et al.  Biochemistry of DNA lesions. , 1985, Radiation research. Supplement.

[87]  P. Jeggo,et al.  X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining. , 1984, Mutation research.

[88]  Jack W. Szostak,et al.  The double-strand-break repair model for recombination , 1983, Cell.

[89]  K. F. Weibezahn,et al.  Radiation induced DNA double strand breaks are rejoined by ligation and recombination processes , 1981, Nucleic Acids Res..

[90]  M. Resnick The repair of double-strand breaks in DNA; a model involving recombination. , 1976, Journal of theoretical biology.

[91]  K. S. Ho,et al.  Induction of DNA double-strand breaks by X-rays in a radiosensitive strain of the yeast Saccharomyces cerevisiae. , 1975, Mutation research.