Mechanisms of systemic low-grade inflammation in HIV patients on long-term suppressive antiretroviral therapy: the inflammasome hypothesis
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V. Appay | E. Lazaro | R. Rossignol | P. Duffau | C. Cognet | B. Faustin | F. Bonnet | J. Déchanet-Merville | B. Pinson | F. Guerville | Isabelle Pellegrin | C. Cazanave | L. Wittkop | C. Tumiotto | O. Leleux | Marine Vialemaringe | Frederic Gabriel
[1] Yan V. Sun,et al. Biological ageing with HIV infection: evaluating the geroscience hypothesis , 2022, The Lancet. Healthy longevity.
[2] R. Vedanthan,et al. How health systems can adapt to a population ageing with HIV and comorbid disease. , 2022, The lancet. HIV.
[3] Emma L. Koppe,et al. Differential recognition of HIV-stimulated IL-1β and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages , 2021, PLoS pathogens.
[4] Jiyuan Zhang,et al. NLRP3 inflammasome induces CD4+ T cell loss in chronically HIV-1-infected patients. , 2021, The Journal of clinical investigation.
[5] I. Soubeyran,et al. Prognostic Role of Inflammasome Components in Human Colorectal Cancer , 2020, Cancers.
[6] David L. Williams,et al. β-Glucan-induced reprogramming of human macrophages inhibits NLRP3 inflammasome activation in cryopyrinopathies. , 2020, The Journal of clinical investigation.
[7] M. Horberg,et al. Comparison of Overall and Comorbidity-Free Life Expectancy Between Insured Adults With and Without HIV Infection, 2000-2016 , 2020, JAMA network open.
[8] I. Rauch,et al. The NAIP/NLRC4 inflammasome in infection and pathology. , 2020, Molecular aspects of medicine.
[9] L. Buée,et al. NLRP3 inflammasome activation drives tau pathology , 2019, Nature.
[10] M. Reilly,et al. Endothelial Foxp1 Suppresses Atherosclerosis via Modulation of Nlrp3 Inflammasome Activation. , 2019, Circulation research.
[11] Michelle E. Wong,et al. The HIV Reservoir in Monocytes and Macrophages , 2019, Front. Immunol..
[12] S. Spector,et al. Human immunodeficiency virus Type‐1 single‐stranded RNA activates the NLRP3 inflammasome and impairs autophagic clearance of damaged mitochondria in human microglia , 2018, Glia.
[13] M. Petzold,et al. Non-AIDS Mortality Is Higher Among Successfully Treated People Living with HIV Compared with Matched HIV-Negative Control Persons: A 15-Year Follow-Up Cohort Study in Sweden , 2018, AIDS patient care and STDs.
[14] E. Lazaro,et al. Multimorbidity, age-related comorbidities and mortality: association of activation, senescence and inflammation markers in HIV adults , 2018, AIDS.
[15] C. Tremblay,et al. HIV induces production of IL-18 from intestinal epithelial cells that increases intestinal permeability and microbial translocation , 2018, PloS one.
[16] L. O’Neill,et al. Metabolic regulation of NLRP3 , 2018, Immunological reviews.
[17] E. Latz,et al. Evidence of inflammasome activation and formation of monocyte-derived ASC specks in HIV-1 positive patients , 2017, AIDS.
[18] M. Heneka,et al. Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease , 2017, Nature.
[19] P. Libby,et al. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease , 2017, The New England journal of medicine.
[20] S. Lawson-Ayayi,et al. Activation, senescence and inflammation markers in HIV patients: association with renal function , 2017, AIDS.
[21] Junlei Chang,et al. Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states , 2017, Nature Medicine.
[22] J. Margolick,et al. Inflammation, Immune Activation, Immunosenescence, and Hormonal Biomarkers in the Frailty-Related Phenotype of Men with or at Risk for HIV , 2016, The Journal of infectious diseases.
[23] A. Copas,et al. Mortality and causes of death in people diagnosed with HIV in the era of highly active antiretroviral therapy compared with the general population: an analysis of a national observational cohort. , 2017, The Lancet. Public health.
[24] K. Hirata,et al. 2-Aminobutyric acid modulates glutathione homeostasis in the myocardium , 2016, Scientific Reports.
[25] J. Brenchley,et al. Gut Mucosal Barrier Dysfunction, Microbial Dysbiosis, and Their Role in HIV-1 Disease Progression. , 2016, The Journal of infectious diseases.
[26] V. Dixit,et al. Inflammasomes: mechanism of assembly, regulation and signalling , 2016, Nature Reviews Immunology.
[27] Xiaoshu Cheng,et al. Caspase-1 Inflammasome Activation Mediates Homocysteine-Induced Pyrop-Apoptosis in Endothelial Cells. , 2016, Circulation research.
[28] P. Reiss,et al. HIV infection is independently associated with frailty in middle-aged HIV type 1-infected individuals compared with similar but uninfected controls , 2016, AIDS.
[29] M. Razzaque,et al. Regulation of mitochondrial oxidative stress by β-arrestins in cultured human cardiac fibroblasts , 2015, Disease Models & Mechanisms.
[30] J. Moreau,et al. Association of immune-activation and senescence markers with non-AIDS-defining comorbidities in HIV-suppressed patients , 2015, AIDS.
[31] Shuzhen Chen,et al. β-arrestin1 Is Critical for the Full Activation of NLRP3 and NLRC4 Inflammasomes , 2015, The Journal of Immunology.
[32] S. Daburon,et al. TCR-dependent sensitization of human γδ T cells to non-myeloid IL-18 in cytomegalovirus and tumor stress surveillance , 2015, Oncoimmunology.
[33] P. Reiss,et al. Cross-sectional comparison of the prevalence of age-associated comorbidities and their risk factors between HIV-infected and uninfected individuals: the AGEhIV cohort study. , 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[34] M. Lederman,et al. Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment. , 2014, The Journal of infectious diseases.
[35] A. Phillips,et al. Health-related quality-of-life of people with HIV in the era of combination antiretroviral treatment: a cross-sectional comparison with the general population , 2018 .
[36] J. Ting,et al. HIV-1 Infection Induces Interleukin-1β Production via TLR8 Protein-dependent and NLRP3 Inflammasome Mechanisms in Human Monocytes* , 2014, The Journal of Biological Chemistry.
[37] D. Duprez,et al. Severity of Cardiovascular Disease Outcomes Among Patients With HIV Is Related to Markers of Inflammation and Coagulation , 2014, Journal of the American Heart Association.
[38] P. Morlat,et al. Causes of death among HIV-infected patients in France in 2010 (national survey): trends since 2000 , 2014, AIDS.
[39] D. Ingram,et al. Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging. , 2013, Cell metabolism.
[40] E. Latz,et al. HIV-1 Induces the First Signal to Activate the NLRP3 Inflammasome in Monocyte-Derived Macrophages , 2013, Intervirology.
[41] R. Ellis,et al. Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection , 2013, AIDS.
[42] G. Häcker,et al. Comparison of (1→3)-β-d-Glucan, Mannan/Anti-Mannan Antibodies, and Cand-Tec Candida Antigen as Serum Biomarkers for Candidemia , 2013, Journal of Clinical Microbiology.
[43] Mardge H. Cohen,et al. Cause-specific life expectancies after 35 years of age for human immunodeficiency syndrome-infected and human immunodeficiency syndrome-negative individuals followed simultaneously in long-term cohort studies, 1984-2008. , 2013, American journal of epidemiology.
[44] I. Grant,et al. Co-morbidities in persons infected with HIV: increased burden with older age and negative effects on health-related quality of life. , 2013, AIDS patient care and STDs.
[45] G. Silvestri,et al. Microbial Translocation in the Pathogenesis of HIV Infection and AIDS , 2013, Clinical Microbiology Reviews.
[46] M. Heneka,et al. NLRP3 is activated in Alzheimer´s disease and contributes to pathology in APP/PS1 mice , 2012, Nature.
[47] L. Kuller,et al. Inflammation, Coagulation and Cardiovascular Disease in HIV-Infected Individuals , 2012, PloS one.
[48] M. Ticchioni,et al. The role of lipopolysaccharide as a marker of immune activation in HIV-1 infected patients: a systematic literature review , 2012, Virology Journal.
[49] A. Roverato,et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[50] J. Capeau. Premature Aging and Premature Age-Related Comorbidities in HIV-Infected Patients: Facts and Hypotheses. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[51] C. Charpentier,et al. Cellular HIV-1 DNA quantification and short-term and long-term response to antiretroviral therapy. , 2011, The Journal of antimicrobial chemotherapy.
[52] Denis Gris,et al. Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling , 2011, Nature Immunology.
[53] Handan Wand,et al. Plasma levels of soluble CD14 independently predict mortality in HIV infection. , 2011, The Journal of infectious diseases.
[54] L. Galluzzi,et al. Mitochondrial control of the NLRP3 inflammasome , 2011, Nature Immunology.
[55] Philippe Besse,et al. Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems , 2011, BMC Bioinformatics.
[56] Anne M. Evans,et al. Organization of GC/MS and LC/MS metabolomics data into chemical libraries , 2010, J. Cheminformatics.
[57] Christine E. Becker,et al. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes , 2010, Nature Immunology.
[58] Egil Lien,et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals , 2010, Nature.
[59] D. Jacobs,et al. Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection. , 2010, The Journal of infectious diseases.
[60] Ross J. Harris,et al. Causes of death in HIV-1-infected patients treated with antiretroviral therapy, 1996-2006: collaborative analysis of 13 HIV cohort studies. , 2010, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[61] C. Sabin,et al. Non-AIDS-defining deaths and immunodeficiency in the era of combination antiretroviral therapy , 2009, AIDS.
[62] Corey D. DeHaven,et al. Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems. , 2009, Analytical chemistry.
[63] Hongqiao Zhang,et al. Glutathione: overview of its protective roles, measurement, and biosynthesis. , 2009, Molecular aspects of medicine.
[64] A. Phillips,et al. HIV infection, antiretroviral treatment, ageing, and non-AIDS related morbidity , 2009, BMJ : British Medical Journal.
[65] Lewis H Kuller,et al. Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection , 2008, PLoS medicine.
[66] J. Margolick,et al. HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailty. , 2007, The journals of gerontology. Series A, Biological sciences and medical sciences.
[67] R. Lefkowitz,et al. Beta-arrestins and cell signaling. , 2007, Annual review of physiology.
[68] S. Mariathasan,et al. Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation , 2007, Nature Reviews Immunology.
[69] R. Lefkowitz,et al. New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors. , 2006, Molecular cell.
[70] M. Churchill,et al. Pathogenesis of macrophage tropic HIV-1. , 2005, Current HIV research.
[71] M. Oppermann. Chemokine receptor CCR5: insights into structure, function, and regulation. , 2004, Cellular signalling.
[72] P. Aukrust,et al. Raised serum levels of interleukin‐18 is associated with disease progression and may contribute to virological treatment failure in HIV‐1‐infected patients , 2003, Clinical and experimental immunology.
[73] R. Morisset,et al. Elevated Levels of Circulating Interleukin-18 in Human Immunodeficiency Virus-Infected Individuals: Role of Peripheral Blood Mononuclear Cells and Implications for AIDS Pathogenesis , 2002, Journal of Virology.
[74] F. Martinon,et al. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. , 2002, Molecular cell.
[75] C. Fox,et al. Macrophages as a source of HIV during opportunistic infections. , 1997, Science.
[76] Y. Benjamini,et al. Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .