2015 Alzheimer's disease facts and figures

[1]  D. Carr,et al.  Does Dementia Caregiving Accelerate Frailty? Findings From the Health and Retirement Study. , 2016, The Gerontologist.

[2]  L. López,et al.  The Effectiveness of a Culturally Sensitive Cognitive Behavioral Group Intervention for Latino Alzheimer's Caregivers. , 2016, The Gerontologist.

[3]  P. Wolf,et al.  Gender and incidence of dementia in the Framingham Heart Study from mid-adult life , 2015, Alzheimer's & Dementia.

[4]  Judy Mullan,et al.  Managing medications: the role of informal caregivers of older adults and people living with dementia. A review of the literature. , 2014, Journal of clinical nursing.

[5]  I. Campbell-Taylor.  Contribution of Alzheimer disease to mortality in the United States , 2014, Neurology.

[6]  B. Mausbach,et al.  Why does placement of persons with Alzheimer's disease into long-term care improve caregivers' well-being? Examination of psychological mediators. , 2014, Psychology and aging.

[7]  B. Mausbach,et al.  Positive Affect and Sleep in Spousal Alzheimer Caregivers: A Longitudinal Study , 2014, Behavioral sleep medicine.

[8]  J. Cummings,et al.  Alzheimer’s disease drug-development pipeline: few candidates, frequent failures , 2014, Alzheimer's Research & Therapy.

[9]  P. Wolf,et al.  TEMPORAL TRENDS IN DEMENTIA INCIDENCE IN THE FRAMINGHAM STUDY , 2014, Alzheimer's & Dementia.

[10]  H. Dodge,et al.  Cohort effects in age-associated cognitive trajectories. , 2014, The journals of gerontology. Series A, Biological sciences and medical sciences.

[11]  M. Klug,et al.  North Dakota assistance program for dementia caregivers lowered utilization, produced savings, and increased empowerment. , 2014, Health affairs.

[12]  N. Ehrlé,et al.  Efficacy of musical interventions in dementia: evidence from a randomized controlled trial. , 2013, Journal of Alzheimer's disease : JAD.

[13]  J. Vaupel,et al.  Physical and cognitive functioning of people older than 90 years: a comparison of two Danish cohorts born 10 years apart , 2013, The Lancet.

[14]  R. Tappen,et al.  Interprofessional education in community-based Alzheimer’s disease diagnosis and treatment , 2013, Journal of interprofessional care.

[15]  Richard Schulz,et al.  A videophone psychosocial intervention for dementia caregivers. , 2013, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[16]  H. Soininen,et al.  The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER): Study design and progress , 2013, Alzheimer's & Dementia.

[17]  B. Mausbach,et al.  A randomized clinical trial of Behavioral Activation (BA) therapy for improving psychological and physical health in dementia caregivers: results of the Pleasant Events Program (PEP). , 2013, Behaviour research and therapy.

[18]  D. Bennett,et al.  Life-span cognitive activity, neuropathologic burden and cognitive aging , 2013, Alzheimer's & Dementia.

[19]  B. Winblad,et al.  Twenty-year changes in dementia occurrence suggest decreasing incidence in central Stockholm, Sweden , 2013, Neurology.

[20]  J. Weuve,et al.  Alzheimer disease in the United States (2010–2050) estimated using the 2010 census , 2013, Neurology.

[21]  A. Bhansali,et al.  Diabetes mellitus and risk of dementia: A meta‐analysis of prospective observational studies , 2013, Journal of diabetes investigation.

[22]  K. Lunetta,et al.  Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. , 2013, JAMA.

[23]  C. Rowe,et al.  Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study , 2013, The Lancet Neurology.

[24]  Yu-Ping Chang,et al.  Sleep disturbance in family caregivers of individuals with dementia: a review of the literature. , 2013, Perspectives in psychiatric care.

[25]  Victoria E. Johnson,et al.  Chronic neuropathologies of single and repetitive TBI: substrates of dementia? , 2013, Nature Reviews Neurology.

[26]  S. Martinez-Ramirez,et al.  Microbleeds do not affect rate of cognitive decline in Alzheimer disease , 2013, Neurology.

[27]  P. Werner,et al.  Current knowledge and future directions about the disclosure of dementia: A systematic review of the first decade of the 21st century , 2013, Alzheimer's & Dementia.

[28]  J. Lee,et al.  Fidelity and acceptability of an adaptive intervention for caregivers: An exploratory study , 2013, Aging & mental health.

[29]  Harald Walach,et al.  Midlife obesity and dementia: Meta‐analysis and adjusted forecast of dementia prevalence in the united states and china , 2013, Obesity.

[30]  Y. Stern.  Cognitive reserve in ageing and Alzheimer's disease , 2012, The Lancet Neurology.

[31]  Anna Kalbarczyk,et al.  Sex and gender differences in Alzheimer's disease: recommendations for future research. , 2012, Journal of women's health.

[32]  D. Rueckert,et al.  Test sequence of CSF and MRI biomarkers for prediction of AD in subjects with MCI , 2012, Neurobiology of Aging.

[33]  J. Berry,et al.  Midlife fitness and the development of chronic conditions in later life. , 2012, Archives of internal medicine.

[34]  D. Bennett,et al.  The natural history of cognitive decline in Alzheimer's disease. , 2012, Psychology and aging.

[35]  R. Mayeux,et al.  Epidemiology of Alzheimer disease. , 2012, Cold Spring Harbor perspectives in medicine.

[36]  F. Grodstein,et al.  Postmenopausal hormone therapy, timing of initiation, APOE and cognitive decline , 2012, Neurobiology of Aging.

[37]  J. Gaugler,et al.  The problem with “problem behaviors”: a systematic review of the association between individual patient behavioral and psychological symptoms and caregiver depression and burden within the dementia patient–caregiver dyad , 2012, International Psychogeriatrics.

[38]  Benjamin F. J. Verhaaren,et al.  Is dementia incidence declining? , 2012, Neurology.

[39]  B. Mausbach,et al.  A longitudinal analysis of the relations among stress, depressive symptoms, leisure satisfaction, and endothelial function in caregivers. , 2012, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[40]  W. Malarkey,et al.  Chronic stress, daily stressors, and circulating inflammatory markers. , 2012, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[41]  Hui-Xin Wang,et al.  Leisure activities, cognition and dementia. , 2012, Biochimica et biophysica acta.

[42]  J. Molinuevo,et al.  Applying the new research diagnostic criteria: MRI findings and neuropsychological correlations of prodromal AD , 2012, International journal of geriatric psychiatry.

[43]  B. Mausbach,et al.  Relationship between chronic stress and carotid intima-media thickness (IMT) in elderly Alzheimer's disease caregivers , 2012, Stress.

[44]  J. Schneider,et al.  National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease , 2012, Alzheimer's & Dementia.

[45]  B. Schmand,et al.  Value of Neuropsychological Tests, Neuroimaging, and Biomarkers for Diagnosing Alzheimer's Disease in Younger and Older Age Cohorts , 2011, Journal of the American Geriatrics Society.

[46]  L. Lannfelt,et al.  Vascular Risk Factors and Dementia: 40-Year Follow-Up of a Population-Based Cohort , 2011, Dementia and Geriatric Cognitive Disorders.

[47]  R. Hamilton,et al.  Diversity and Disparity in Dementia: The Impact of Ethnoracial Differences in Alzheimer Disease , 2011, Alzheimer disease and associated disorders.

[48]  Ronald C Petersen,et al.  Outcomes of mild cognitive impairment by definition: a population study. , 2011, Archives of neurology.

[49]  K. Anstey,et al.  Body mass index in midlife and late‐life as a risk factor for dementia: a meta‐analysis of prospective studies , 2011, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[50]  Nick C Fox,et al.  The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[51]  Denise C. Park,et al.  Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[52]  David Llewellyn,et al.  Caring for Individuals with Dementia and Cognitive Impairment, Not Dementia: Findings from the Aging, Demographics, and Memory Study , 2011, Journal of the American Geriatrics Society.

[53]  S. Leurgans,et al.  Sources of variability in estimates of the prevalence of Alzheimer’s disease in the United States , 2011, Alzheimer's & Dementia.

[54]  A. Zaleta,et al.  Patient-Centered Communication During the Disclosure of a Dementia Diagnosis , 2010, American journal of Alzheimer's disease and other dementias.

[55]  Yaakov Stern,et al.  Food combination and Alzheimer disease risk: a protective diet. , 2010, Archives of neurology.

[56]  F. Jessen,et al.  Prediction of dementia by subjective memory impairment: effects of severity and temporal association with cognitive impairment. , 2010, Archives of general psychiatry.

[57]  N. Pedersen,et al.  Cognitive engagement and cognitive aging: is openness protective? , 2010, Psychology and aging.

[58]  Daniel D Christensen,et al.  The art of sharing the diagnosis and management of Alzheimer's disease with patients and caregivers: recommendations of an expert consensus panel. , 2010, Primary care companion to the Journal of clinical psychiatry.

[59]  I. Lieberburg,et al.  Lethality of Alzheimer Disease and Its Impact on Nursing Home Placement , 2010, Alzheimer Disease and Associated Disorders.

[60]  Wei Zhu,et al.  Outcome over seven years of healthy adults with and without subjective cognitive impairment , 2010, Alzheimer's & Dementia.

[61]  J. R. Scotti,et al.  Available From , 1973 .

[62]  M. Kivipelto,et al.  Midlife Serum Cholesterol and Increased Risk of Alzheimer’s and Vascular Dementia Three Decades Later , 2009, Dementia and Geriatric Cognitive Disorders.

[63]  S. Leurgans,et al.  The neuropathology of probable Alzheimer disease and mild cognitive impairment , 2009, Annals of neurology.

[64]  C. Jack,et al.  Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease , 2009, Brain : a journal of neurology.

[65]  C. Tzourio,et al.  Vascular risk factors and dementia , 2009, Neurology.

[66]  David A. Bennett,et al.  Social Engagement and Cognitive Function in Old Age , 2009, Experimental aging research.

[67]  C. DeCarli,et al.  The brain in the age of old: The hippocampal formation is targeted differentially by diseases of late life , 2008, Annals of neurology.

[68]  Y. Stern,et al.  Survival in Alzheimer disease , 2008, Neurology.

[69]  R. Katzman.,et al.  The Prevalence and Malignancy of Alzheimer Disease A Major Killer , 2008, Alzheimer's & Dementia.

[70]  S. Melquist,et al.  Risk‐reducing effect of education in Alzheimer's disease , 2008, International journal of geriatric psychiatry.

[71]  Cathy C. Schubert,et al.  Acute Care Utilization by Dementia Caregivers Within Urban Primary Care Practices , 2008, Journal of General Internal Medicine.

[72]  J. Manly,et al.  Diagnosis and assessment of Alzheimer's disease in diverse populations , 2008, Alzheimer's & Dementia.

[73]  M. Johnston,et al.  Appropriate disclosure of a diagnosis of dementia: identifying the key behaviours of 'best practice' , 2008, BMC health services research.

[74]  Yaakov Stern,et al.  Frequency and course of mild cognitive impairment in a multiethnic community , 2008, Annals of neurology.

[75]  J. Karlawish,et al.  Trends in the prevalence and mortality of cognitive impairment in the United States: Is there evidence of a compression of cognitive morbidity? , 2008, Alzheimer's & Dementia.

[76]  C. Xiong,et al.  Reaction to a Dementia Diagnosis in Individuals with Alzheimer's Disease and Mild Cognitive Impairment , 2008, Journal of the American Geriatrics Society.

[77]  David A. Bennett,et al.  Mixed brain pathologies account for most dementia cases in community-dwelling older persons , 2007, Neurology.

[78]  K. Langa,et al.  Prevalence of Dementia in the United States: The Aging, Demographics, and Memory Study , 2007, Neuroepidemiology.

[79]  M. McCabe,et al.  Effectiveness of staff training programs for behavioral problems among older people with dementia , 2007, Aging & mental health.

[80]  K. Jellinger,et al.  Neuropathological evaluation of mixed dementia , 2007, Journal of the Neurological Sciences.

[81]  J. Lindsay,et al.  Mapping the connections between education and dementia , 2007, Journal of clinical and experimental neuropsychology.

[82]  J. Morris,et al.  Education and Alzheimer disease without dementia , 2007, Neurology.

[83]  K. Jellinger.  The enigma of mixed dementia , 2007, Alzheimer's & Dementia.

[84]  Naihua Duan,et al.  The Effect of a Disease Management Intervention on Quality and Outcomes of Dementia Care , 2006, Annals of Internal Medicine.

[85]  L. Fredman,et al.  Leisure-time exercise and overall physical activity in older women caregivers and non-caregivers from the Caregiver-SOF Study. , 2006, Preventive medicine.

[86]  P. Scheltens,et al.  Impact of diagnostic disclosure in dementia on patients and carers: Qualitative case series analysis , 2006, Aging & mental health.

[87]  P. Scheltens,et al.  Receiving a diagnosis of dementia , 2006 .

[88]  Y. Stern.  Cognitive Reserve and Alzheimer Disease , 2006, Alzheimer disease and associated disorders.

[89]  Lenore J Launer,et al.  The effect of social engagement on incident dementia: the Honolulu-Asia Aging Study. , 2006, American journal of epidemiology.

[90]  Laura Fratiglioni,et al.  Mental, Physical and Social Components in Leisure Activities Equally Contribute to Decrease Dementia Risk , 2006, Dementia and Geriatric Cognitive Disorders.

[91]  N. Kutner,et al.  Impediments to Timely Diagnosis of Alzheimer's Disease in African Americans , 2005, Journal of the American Geriatrics Society.

[92]  K. Langa,et al.  The Aging, Demographics, and Memory Study: Study Design and Methods , 2005, Neuroepidemiology.

[93]  J. Morris,et al.  Early-Stage Alzheimer Disease Represents Increased Suicidal Risk in Relation to Later Stages , 2005, Alzheimer disease and associated disorders.

[94]  S. Marshall,et al.  Association between Recurrent Concussion and Late-Life Cognitive Impairment in Retired Professional Football Players , 2005, Neurosurgery.

[95]  Marc Verny,et al.  [Survival after initial diagnosis of Alzheimer disease]. , 2005, Psychologie & neuropsychiatrie du vieillissement.

[96]  L. Riley,et al.  The Sandwich Generation: Challenges and Coping Strategies of Multigenerational Families , 2005 .

[97]  Paul G. Ince,et al.  Vascular pathologies and cognition in a population-based cohort of elderly people , 2004, Journal of the Neurological Sciences.

[98]  W. Selman,et al.  Management of normal pressure hydrocephalus. , 2004, American family physician.

[99]  M. Orrell,et al.  Life events, depression and social support in dementia. , 2004, The British journal of clinical psychology.

[100]  B. Winblad,et al.  An active and socially integrated lifestyle in late life might protect against dementia , 2004, The Lancet Neurology.

[101]  A. M. Clarfield,et al.  The decreasing prevalence of reversible dementias: an updated meta-analysis. , 2003, Archives of internal medicine.

[102]  John Breitner,et al.  Prevalence and classification of mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 1. , 2003, Archives of neurology.

[103]  D. Bennett,et al.  Alzheimer disease in the US population: prevalence estimates using the 2000 census. , 2003, Archives of neurology.

[104]  Henry Brodaty,et al.  Meta‐Analysis of Psychosocial Interventions for Caregivers of People with Dementia , 2003, Journal of the American Geriatrics Society.

[105]  K. Heilman,et al.  Relative Frequencies of Alzheimer Disease, Lewy Body, Vascular and Frontotemporal Dementia, and Hippocampal Sclerosis in the State of Florida Brain Bank , 2002, Alzheimer disease and associated disorders.

[106]  Laura Fratiglioni,et al.  Late-life engagement in social and leisure activities is associated with a decreased risk of dementia: a longitudinal study from the Kungsholmen project. , 2002, American journal of epidemiology.

[107]  J. Gaugler,et al.  Family Care for Older Adults With Disabilities: Toward More Targeted and Interpretable Research , 2002, International journal of aging & human development.

[108]  L. Fitten,et al.  Frequency of Alzheimer's Disease and Other Dementias in a Community Outreach Sample of Hispanics , 2001, Journal of the American Geriatrics Society.

[109]  L A Beckett,et al.  Is the risk of developing Alzheimer's disease greater for women than for men? , 2001, American journal of epidemiology.

[110]  L. Kuller,et al.  Estrogen use, APOE, and cognitive decline , 2000, Neurology.

[111]  R. Schulz,et al.  Caregiving as a risk factor for mortality: the Caregiver Health Effects Study. , 1999, JAMA.

[112]  R M Kaplan,et al.  Shared decision making in clinical medicine: past research and future directions. , 1999, American journal of preventive medicine.

[113]  D. Dickenson,et al.  The capacity to make decisions in dementia: some contemporary issues , 1999, International journal of geriatric psychiatry.

[114]  M. Ganguli,et al.  Reporting of Dementia on Death Certificates: A Community Study , 1999, Journal of the American Geriatrics Society.

[115]  C. Patterson,et al.  The Recognition, Assessment and Management of Dementing Disorders: Conclusions from the Canadian Consensus Conference on Dementia , 1999, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[116]  K. Hepburn,et al.  Reducing caregiver burden: a randomized psychoeducational intervention for caregivers of persons with dementia. , 1999, The Gerontologist.

[117]  C. Beck,et al.  Enabling and empowering certified nursing assistants for quality dementia care , 1999, International journal of geriatric psychiatry.

[118]  R Brookmeyer,et al.  Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. , 1998, American journal of public health.

[119]  B. Meyers.  Telling patients they have Alzheimer's disease , 1997, BMJ.

[120]  D. Coakley,et al.  Family members' attitudes toward telling the patient with Alzheimer's disease their diagnosis , 1996, BMJ.

[121]  W. Malarkey,et al.  Slowing of wound healing by psychological stress , 1995, The Lancet.

[122]  B. McCurdy,et al.  Appendices , 1994 .

[123]  A. Mulley,et al.  Developing shared decision-making programs to improve the quality of health care. , 1992, QRB. Quality review bulletin.

[124]  G. Spitze,et al.  More Evidence on Women (and Men) in the Middle , 1990, Research on aging.

[125]  E. Brody.  "Women in the middle" and family help to older people. , 1981, The Gerontologist.

[126]  F. Eugene Yates,et al.  The national center for health statistics , 1973, Annals of Biomedical Engineering.

[127]  Manjit,et al.  Neurology , 1912, NeuroImage.

[128]  Alejandro F Frangi,et al.  Modifiable lifestyle factors in dementia: a systematic review of longitudinal observational cohort studies. , 2014, Journal of Alzheimer's disease : JAD.

[129]  Jin-Tai Yu,et al.  Midlife vascular risk factors and the risk of Alzheimer's disease: a systematic review and meta-analysis. , 2014, Journal of Alzheimer's disease : JAD.

[130]  F. Svenaeus.  American Psychiatric Association, 2013. Diagnostic and statistical manual of mental disorders, 5th ed. American Psychiatric Publishing: Washington, DC. 991 pp., ISBN: 978-0890425558. Price: $122.70 , 2014 .

[131]  G. Eslick,et al.  Type 2 diabetes as a risk factor for Alzheimer's disease: the confounders, interactions, and neuropathology associated with this relationship. , 2013, Epidemiologic reviews.

[132]  Ronda C. Talley,et al.  Caregiving for Alzheimer’s Disease and Related Disorders , 2013 .

[133]  R. Honea,et al.  Maternal family history is associated with Alzheimer's disease biomarkers. , 2012, Journal of Alzheimer's disease : JAD.

[134]  Sean D Sullivan,et al.  Review and meta-analysis of biomarkers and diagnostic imaging in Alzheimer's disease. , 2011, Journal of Alzheimer's disease : JAD.

[135]  J. Ballenger,et al.  Dietary patterns and risk of dementia: The Three-City cohort study , 2009 .

[136]  Bruno Vellas,et al.  Diagnosis and Treatment of Patients with Severe Alzheimer’s Disease , 2009, Drugs & aging.

[137]  S. Ukraintseva,et al.  Declining prevalence of dementia in the U.S. elderly population. , 2005, Advances in gerontology = Uspekhi gerontologii.

[138]  E. A. Shores,et al.  Traumatic Brain Injury as a Risk Factor for Alzheimer's Disease: A Review , 2004, Neuropsychology Review.

[139]  M. C. Smith,et al.  Training nursing assistants to care for nursing home residents with dementia. , 2000 .

[140]  H. Eglit.  Diagnosis, Management and Treatment of Dementia , 1999 .

[141]  E. Tangalos,et al.  Mild Cognitive Impairment Clinical Characterization and Outcome , 1999 .