Nebennierenkrisen und Hypoglykämien bei Kindern mit klassischem adrenogenitalem Syndrom (AGS) // Adrenal crisis and hypoglycemia in children with congenital adrenal hyperplasia (CAH)

Adrenal crisis and hypoglycemia in children with congenital adrenal hyperplasia (CAH). Patients with classic congenital adrenal hyperplasia (CAH) have a life-long risk for potentially leathal adrenal crisis. Toddlers and infants are also at risk for hypoglycemia. Especially infants with CAH have a higher seizure risk as a consequence of hyponatremia and hypoglycemia. Typical trigger situations for adrenal crisis are infectious diseases, especially gastroenteritis. Patients with CAH and their family members should be educated in terms of compliance with glucocorticoid medication, adequate stress dosing (usually triple to five fold elevated oral hydrocortisone dosage) and intramuscular injection of hydrocortisone or prednisone. J Klin Endokrinol Stoffw 2016; 9 (4): 106–7.