PIK3R1 underexpression is an independent prognostic marker in breast cancer
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Etienne Rouleau | Rosette Lidereau | Didier Meseure | S. Vacher | I. Bièche | R. Lidereau | F. Spyratos | D. Meseure | E. Rouleau | Ivan Bièche | M. Čížková | M. Trassard | A. Susini | Dana Mlcuchova | C. Callens | Magdalena Cizkova | Aurélie Susini | Sophie Vacher | Martine Trassard | Dana Mlcuchova | Celine Callens | Frederique Spyratos | Aurélie Susini
[1] L. Skoog,et al. PIK3CA Mutations and PTEN Loss Correlate with Similar Prognostic Factors and Are Not Mutually Exclusive in Breast Cancer , 2007, Clinical Cancer Research.
[2] B. Iacopetta,et al. PIK3CA mutations in breast cancer are associated with poor outcome , 2006, Breast Cancer Research and Treatment.
[3] Masahiro Uchino,et al. Nuclear β-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells , 2010, BMC Cancer.
[4] S. Vacher,et al. Profiling of EGFR mRNA and protein expression in 471 breast cancers compared with 10 normal tissues: A candidate biomarker to predict EGFR inhibitor effectiveness , 2012, International journal of cancer.
[5] M. Troxell,et al. Phosphatidylinositol-3-kinase and AKT1 mutations occur early in breast carcinoma , 2010, Breast Cancer Research and Treatment.
[6] Ji Luo,et al. The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling. , 2010, Cancer research.
[7] Aleix Prat Aparicio. Comprehensive molecular portraits of human breast tumours , 2012 .
[8] J. Baselga. Targeting the phosphoinositide-3 (PI3) kinase pathway in breast cancer. , 2011, The oncologist.
[9] M. Pike,et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples. , 1977, British Journal of Cancer.
[10] J. Baselga,et al. Phosphoinositide 3-Kinase Mutations in Breast Cancer: A “Good” Activating Mutation? , 2009, Clinical Cancer Research.
[11] I. Bièche,et al. Fluorescence in situ hybridization and immunohistochemical assays for HER-2/neu status determination: application to node-negative breast cancer. , 2001, Archives of pathology & laboratory medicine.
[12] Rosette Lidereau,et al. PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups , 2012, Breast Cancer Research.
[13] A. Marchetti,et al. Different Prognostic Roles of Mutations in the Helical and Kinase Domains of the PIK3CA Gene in Breast Carcinomas , 2007, Clinical Cancer Research.
[14] Yonghong Xiao,et al. GOLPH3 modulates mTOR signaling and rapamycin sensitivity in cancer , 2009, Nature.
[15] T. Tsuruo,et al. Akt/Protein Kinase B-Dependent Phosphorylation and Inactivation of WEE1Hu Promote Cell Cycle Progression at G2/M Transition , 2005, Molecular and Cellular Biology.
[16] P. Vogt,et al. Cancer-specific mutations in PIK3CA are oncogenic in vivo , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[17] I. Bièche,et al. Real-time RT-PCR: a complementary method to detect HER-2 status in breast carcinoma. , 2005, Anticancer research.
[18] Zev A. Binder,et al. Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells , 2011, Oncotarget.
[19] E. Kaplan,et al. Nonparametric Estimation from Incomplete Observations , 1958 .
[20] J. Backer,et al. Regulation of the p85/p110 Phosphatidylinositol 3′-Kinase: Stabilization and Inhibition of the p110α Catalytic Subunit by the p85 Regulatory Subunit , 1998, Molecular and Cellular Biology.
[21] W. Gerald,et al. PIK3CA Mutation Associates with Improved Outcome in Breast Cancer , 2009, Clinical Cancer Research.
[22] Joshua F. McMichael,et al. Whole Genome Analysis Informs Breast Cancer Response to Aromatase Inhibition , 2012, Nature.
[23] Zhifu Sun,et al. A Gene Expression Signature Predicts Survival of Patients with Stage I Non-Small Cell Lung Cancer , 2006, PLoS medicine.
[24] T. Mukohara,et al. Association between gain-of-function mutations in PIK3CA and resistance to HER2-targeted agents in HER2-amplified breast cancer cell lines. , 2010, Annals of oncology : official journal of the European Society for Medical Oncology.
[25] Zhi Hu,et al. An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer. , 2008, Cancer research.
[26] I. Bièche,et al. Quantification of estrogen receptor α and β expression in sporadic breast cancer , 2001, Oncogene.
[27] H. Gómez,et al. The phosphatidyl inositol 3-kinase/AKT signaling pathway in breast cancer , 2010, Cancer and Metastasis Reviews.
[28] M. Girvin,et al. Mechanism of Constitutive Phosphoinositide 3-Kinase Activation by Oncogenic Mutants of the p85 Regulatory Subunit* , 2005, Journal of Biological Chemistry.
[29] D.,et al. Regression Models and Life-Tables , 2022 .
[30] I. Bièche,et al. Quantification of estrogen receptor alpha and beta expression in sporadic breast cancer. , 2001, Oncogene.
[31] B. Peters,et al. Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation. , 2009, Cancer cell.
[32] A. Laenkholm,et al. PIK3CA mutations, PTEN, and pHER2 expression and impact on outcome in HER2-positive early-stage breast cancer patients treated with adjuvant chemotherapy and trastuzumab. , 2012, Annals of oncology : official journal of the European Society for Medical Oncology.
[33] Steven J. M. Jones,et al. Comprehensive molecular portraits of human breast tumors , 2012, Nature.
[34] Hanina Hibshoosh,et al. PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. , 2005, Cancer research.
[35] Miyuki Yoshida,et al. The Selective Class I PI3K Inhibitor CH5132799 Targets Human Cancers Harboring Oncogenic PIK3CA Mutations , 2011, Clinical Cancer Research.
[36] Steven J. M. Jones,et al. Comprehensive molecular portraits of human breast tumours , 2013 .
[37] S. Hilsenbeck,et al. Loss of phosphatase and tensin homolog or phosphoinositol-3 kinase activation and response to trastuzumab or lapatinib in human epidermal growth factor receptor 2-overexpressing locally advanced breast cancers. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[38] M. Monden,et al. Clinicopathologic Analysis of Breast Cancers with PIK3CA Mutations in Japanese Women , 2007, Clinical Cancer Research.
[39] I. Bièche,et al. Real-time reverse transcription-PCR assay for future management of ERBB2-based clinical applications. , 1999, Clinical chemistry.
[40] S. Rodriguez-Zas,et al. Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival , 2011, BMC Medical Genomics.
[41] M. Loda,et al. The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[42] G. Mills,et al. High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability. , 2011, Cancer discovery.
[43] W. Gerald,et al. Human Cancer Biology PIK 3 CA Mutation Associates with Improved Outcome in Breast Cancer , 2009 .
[44] M. Loda,et al. The oncogenic properties of mutant p110α and p110β phosphatidylinositol 3-kinases in human mammary epithelial cells , 2005 .