Genome-wide transcriptomics leads to the identification of deregulated genes after deferasirox therapy in low-risk MDS patients
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J. Hernández-Rivas | B. Arrizabalaga | M. Abáigar | M. Díez-Campelo | E. Lumbreras | R. de Paz | T. González | Ana A. Martín | M. del Rey | D. López | S. Erquiaga | A. Vicente | J. Sánchez
[1] F. Sánchez-Guijo,et al. Deferasirox reduces oxidative DNA damage in bone marrow cells from myelodysplastic patients and improves their differentiation capacity , 2019, British journal of haematology.
[2] M. Vignetti,et al. Update of the GIMEMA MDS0306 study: Deferasirox for lower risk transfusion‐dependent patients with myelodysplastic syndromes , 2019, European journal of haematology.
[3] B. Gallie,et al. Correction: Single-center retrospective study of the effectiveness and toxicity of the oral iron chelating drugs deferiprone and deferasirox , 2019, PloS one.
[4] K. King,et al. The Role of Interferon-Gamma in Hematopoietic Stem Cell Development, Homeostasis, and Disease , 2018, Current Stem Cell Reports.
[5] L. Lyle,et al. Iron Overload in Myelodysplastic Syndromes: Pathophysiology, Consequences, Diagnosis, and Treatment , 2018, Journal of the advanced practitioner in oncology.
[6] J. Arnaud,et al. Reactive oxygen species levels control NF-κB activation by low dose deferasirox in erythroid progenitors of low risk myelodysplastic syndromes , 2017, Oncotarget.
[7] A. Levis,et al. Iron‐chelating therapy with deferasirox in transfusion‐dependent, higher risk myelodysplastic syndromes: a retrospective, multicentre study , 2017, British journal of haematology.
[8] Aiping Qi,et al. Reactive oxygen species mediated T lymphocyte abnormalities in an iron-overloaded mouse model and iron-overloaded patients with myelodysplastic syndromes , 2017, Annals of Hematology.
[9] E. Anguita,et al. Transcription Factor GFI1B in Health and Disease , 2017, Front. Oncol..
[10] N. Gattermann. Iron overload in myelodysplastic syndromes (MDS) , 2017, International Journal of Hematology.
[11] N. Mifsud,et al. The oral iron chelator deferasirox inhibits NF‐κB mediated gene expression without impacting on proximal activation: implications for myelodysplasia and aplastic anaemia , 2015, British journal of haematology.
[12] Xin Huang,et al. MicroRNA-146a and MicroRNA-146b Regulate Human Dendritic Cell Apoptosis and Cytokine Production by Targeting TRAF6 and IRAK1 Proteins* , 2014, The Journal of Biological Chemistry.
[13] M. Vignetti,et al. Deferasirox for transfusion‐dependent patients with myelodysplastic syndromes: safety, efficacy, and beyond (GIMEMA MDS0306 Trial) , 2014, European journal of haematology.
[14] M. Nichelatti,et al. Hematological improvement during iron-chelation therapy in myelodysplastic syndromes: the experience of the "Rete Ematologica Lombarda". , 2013, Leukemia research.
[15] J. Hernández-Rivas,et al. Genome-wide profiling of methylation identifies novel targets with aberrant hypermethylation and reduced expression in low-risk myelodysplastic syndromes , 2013, Leukemia.
[16] P. Fenaux,et al. Hematologic responses to deferasirox therapy in transfusion-dependent patients with myelodysplastic syndromes , 2012, Haematologica.
[17] D. Steensma,et al. Deferasirox reduces serum ferritin and labile plasma iron in RBC transfusion-dependent patients with myelodysplastic syndrome. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[18] C. Schumann,et al. Results from a 1-year, open-label, single arm, multi-center trial evaluating the efficacy and safety of oral Deferasirox in patients diagnosed with low and int-1 risk myelodysplastic syndrome (MDS) and transfusion-dependent iron overload , 2012, Annals of Hematology.
[19] Ryan M. O’Connell,et al. MicroRNA-125b Potentiates Macrophage Activation , 2011, The Journal of Immunology.
[20] Debashis Sahoo,et al. MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets , 2010, Proceedings of the National Academy of Sciences.
[21] D. Cilloni,et al. Deferasirox is a powerful NF-κB inhibitor in myelodysplastic cells and in leukemia cell lines acting independently from cell iron deprivation by chelation and reactive oxygen species scavenging , 2010, Haematologica.
[22] Aadel A. Chaudhuri,et al. MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output , 2010, Proceedings of the National Academy of Sciences.
[23] Torsten Haferlach,et al. Microarray-based classifiers and prognosis models identify subgroups with distinct clinical outcomes and high risk of AML transformation of myelodysplastic syndrome. , 2009, Blood.
[24] C. Bloomfield,et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. , 2009, Blood.
[25] S. Okabe,et al. The oral iron chelator deferasirox represses signaling through the mTOR in myeloid leukemia cells by enhancing expression of REDD1 , 2009, Cancer science.
[26] Brad T. Sherman,et al. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists , 2008, Nucleic acids research.
[27] Brad T. Sherman,et al. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.
[28] Muller Fabbri,et al. Modulation of miR-155 and miR-125b Levels following Lipopolysaccharide/TNF-α Stimulation and Their Possible Roles in Regulating the Response to Endotoxin Shock1 , 2007, The Journal of Immunology.
[29] H. Cario,et al. Recent developments in iron chelation therapy. , 2007, Klinische Padiatrie.
[30] J. Carazo,et al. GENECODIS: a web-based tool for finding significant concurrent annotations in gene lists , 2007, Genome Biology.
[31] Terence P. Speed,et al. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias , 2003, Bioinform..
[32] F. Galactéros. [Secondary iron overload]. , 1998, La Revue du praticien.
[33] G. Brittenham,et al. Iron-chelating therapy and the treatment of thalassemia. , 1997, Blood.