Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells

[1]  R. Chen,et al.  Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance , 2009, Cell cycle.

[2]  L. Dubeau,et al.  The cell of origin of ovarian epithelial tumours. , 2008, The Lancet. Oncology.

[3]  K. Brennand,et al.  Normal ovarian surface epithelial label-retaining cells exhibit stem/progenitor cell characteristics , 2008, Proceedings of the National Academy of Sciences.

[4]  I. Shih,et al.  Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion. , 2008, Cancer research.

[5]  Curt Balch,et al.  Identification and characterization of ovarian cancer-initiating cells from primary human tumors. , 2008, Cancer research.

[6]  Joaquín Dopazo,et al.  Babelomics: advanced functional profiling of transcriptomics, proteomics and genomics experiments , 2008, Nucleic Acids Res..

[7]  Jay W. Wright,et al.  Induction of proliferation in the primate ovarian surface epithelium in vivo. , 2008, Human reproduction.

[8]  R. Nusse,et al.  Wnt signaling and stem cell control , 2008, Cell Research.

[9]  A. Hägglund,et al.  Lhx2 Expression Promotes Self-Renewal of a Distinct Multipotential Hematopoietic Progenitor Cell in Embryonic Stem Cell-Derived Embryoid Bodies , 2008, PloS one.

[10]  Y. Jiang,et al.  The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin , 2008, Oncogene.

[11]  Shinya Watanabe,et al.  NOTCH3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells. , 2008, Cancer research.

[12]  Susan Halabi,et al.  Cyclin E Overexpression in Epithelial Ovarian Cancer Characterizes an Etiologic Subgroup , 2008, Cancer Epidemiology Biomarkers & Prevention.

[13]  J. Knoblich,et al.  Mechanisms of Asymmetric Stem Cell Division , 2008, Cell.

[14]  Sean J. Morrison,et al.  Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life , 2008, Cell.

[15]  I. Weissman,et al.  Stems Cells and the Pathways to Aging and Cancer , 2008, Cell.

[16]  D. Scadden,et al.  Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation , 2008, Nature Reviews Genetics.

[17]  A. Martinez Arias,et al.  Wnt/Notch signalling and information processing during development , 2008, Development.

[18]  Seiichi Mori,et al.  An E2F1-dependent gene expression program that determines the balance between proliferation and cell death. , 2008, Cancer cell.

[19]  H. Yamamoto,et al.  Transcriptional silencing of hedgehog‐interacting protein by CpG hypermethylation and chromatic structure in human gastrointestinal cancer , 2007, The Journal of pathology.

[20]  D. Bodine,et al.  Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation , 2007, Proceedings of the National Academy of Sciences.

[21]  Suet Yi Leung,et al.  Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors , 2007, Proceedings of the National Academy of Sciences.

[22]  A. Walch,et al.  Predictive Value of Aurora-A/STK15 Expression for Late Stage Epithelial Ovarian Cancer Patients Treated by Adjuvant Chemotherapy , 2007, Clinical Cancer Research.

[23]  E. Fuchs,et al.  Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling , 2007, Proceedings of the National Academy of Sciences.

[24]  H. Moses,et al.  A tale of two proteins: Differential roles and regulation of Smad2 and Smad3 in TGF‐β signaling , 2007, Journal of cellular biochemistry.

[25]  Michael J. Birrer,et al.  Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling , 2007, Oncogene.

[26]  W. Murdoch,et al.  Morphologic responses of the mouse ovarian surface epithelium to ovulation and steroid hormonal milieu. , 2007, Experimental biology and medicine.

[27]  M. Clarke,et al.  Cancer stem cells: models and concepts. , 2007, Annual review of medicine.

[28]  J. Garber,et al.  A candidate precursor to serous carcinoma that originates in the distal fallopian tube , 2007 .

[29]  S. Friedman.  Transcriptional regulation of stellate cell activation , 2006, Journal of gastroenterology and hepatology.

[30]  S. Hanash,et al.  Cellular retinoic acid-binding protein II is a direct transcriptional target of MycN in neuroblastoma. , 2006, Cancer research.

[31]  J. Whitesides,et al.  Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[32]  Elaine Fuchs,et al.  Lhx2 Maintains Stem Cell Character in Hair Follicles , 2006, Science.

[33]  Sean J. Morrison,et al.  Asymmetric and symmetric stem-cell divisions in development and cancer , 2006, Nature.

[34]  Tian-Li Wang,et al.  Notch3 gene amplification in ovarian cancer. , 2006, Cancer research.

[35]  G. Mills,et al.  Cyclin E expression is correlated with tumor progression and predicts a poor prognosis in patients with ovarian carcinoma , 2006, Cancer.

[36]  Christopher P Crum,et al.  The Tubal Fimbria Is a Preferred Site for Early Adenocarcinoma in Women With Familial Ovarian Cancer Syndrome , 2006, The American journal of surgical pathology.

[37]  Pablo Tamayo,et al.  Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[38]  Gordon B Mills,et al.  Patterns of Gene Expression in Different Histotypes of Epithelial Ovarian Cancer Correlate with Those in Normal Fallopian Tube, Endometrium, and Colon , 2005, Clinical Cancer Research.

[39]  F. Kubo,et al.  Wnt2b inhibits differentiation of retinal progenitor cells in the absence of Notch activity by downregulating the expression of proneural genes , 2005, Development.

[40]  Wenjun Cheng,et al.  Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract , 2005, Nature Medicine.

[41]  P. Collas,et al.  Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture. , 2005, Molecular biology of the cell.

[42]  Tian-Li Wang,et al.  Apolipoprotein E is required for cell proliferation and survival in ovarian cancer. , 2005, Cancer research.

[43]  David M. Berman,et al.  Tissue repair and stem cell renewal in carcinogenesis , 2004, Nature.

[44]  Ossama Tawfik,et al.  BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt–β-catenin signaling , 2004, Nature Genetics.

[45]  D. Sassoon,et al.  Wnt7a Is a Suppressor of Cell Death in the Female Reproductive Tract and Is Required for Postnatal and Estrogen-Mediated Growth1 , 2004, Biology of reproduction.

[46]  W. Murdoch,et al.  Oxidative Damage to DNA of Ovarian Surface Epithelial Cells Affected by Ovulation: Carcinogenic Implication and Chemoprevention , 2004, Experimental biology and medicine.

[47]  I. Bedrosian,et al.  Cyclin E deregulation alters the biologic properties of ovarian cancer cells , 2004, Oncogene.

[48]  Eric C. Lai,et al.  Notch signaling: control of cell communication and cell fate , 2004, Development.

[49]  Ash A. Alizadeh,et al.  Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds , 2004, PLoS biology.

[50]  P. V. van Diest,et al.  BRCA1/2-related ovarian cancers are of tubal origin: a hypothesis. , 2003, Gynecologic oncology.

[51]  Purvesh Khatri,et al.  Onto-Tools, the toolkit of the modern biologist: Onto-Express, Onto-Compare, Onto-Design and Onto-Translate , 2003, Nucleic Acids Res..

[52]  S. Grimmond,et al.  Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells , 2002, Oncogene.

[53]  I. Weissman,et al.  Stem cells, cancer, and cancer stem cells , 2001, Nature.

[54]  L. Buttitta,et al.  Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[55]  J. Taipale,et al.  The Hedgehog and Wnt signalling pathways in cancer , 2001, Nature.

[56]  R. Puri,et al.  Molecular cloning of pituitary tumor transforming gene 1 from ovarian tumors and its expression in tumors. , 2001, Cancer letters.

[57]  J. Aruga,et al.  Transcription Factors Zic1 and Zic2 Bind and Transactivate the Apolipoprotein E Gene Promoter* , 2001, The Journal of Biological Chemistry.

[58]  P. Chambon,et al.  The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures. , 2001, Genes & development.

[59]  O. Colvin,et al.  Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[60]  M. Weller,et al.  Transforming growth factor-β and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth , 1999, Cell and Tissue Research.

[61]  L. Dubeau.  The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: does the emperor have no clothes? , 1999, Gynecologic oncology.

[62]  F. Dilworth,et al.  Identification of the Retinoic Acid-inducible All-trans-retinoic Acid 4-Hydroxylase* , 1996, The Journal of Biological Chemistry.

[63]  R. Zeillinger,et al.  Cyclin gene amplification and overexpression in breast and ovarian cancers: Evidence for the selection of cyclin D1 in breast and cyclin E in ovarian tumors , 1996, International journal of cancer.

[64]  R. Scully,et al.  Early de novo ovarian carcinoma. A study of fourteen cases , 1994, Cancer.

[65]  D. Bell.  Ovarian surface epithelial-stromal tumors. , 1991, Human pathology.

[66]  M F Fathalla,et al.  Incessant ovulation--a factor in ovarian neoplasia? , 1971, Lancet.

[67]  E. Allen,et al.  Attempts to stimulate proliferation of the germinal epithelium of the ovary , 1942 .

[68]  S. Sell.  History of Cancer Stem Cells , 2009 .

[69]  Archana Dhasarathy,et al.  The Transcription Factor Snail Mediates Epithelial to Mesenchymal Transitions by Repression of Estrogen Receptor - , 2007 .

[70]  Sun Young Park,et al.  Transforming growth factor-beta1 represses E-cadherin production via slug expression in lens epithelial cells. , 2007, Investigative ophthalmology & visual science.

[71]  H. Sive,et al.  The zic1 gene is an activator of Wnt signaling. , 2006, The International journal of developmental biology.

[72]  T. Colgan,et al.  Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers. , 2006, Gynecologic oncology.

[73]  P. Leung,et al.  Ovarian surface epithelium: biology, endocrinology, and pathology. , 2001, Endocrine reviews.

[74]  S. Byers,et al.  Cross-regulation of beta-catenin-LEF/TCF and retinoid signaling pathways. , 1999, Current biology : CB.

[75]  K. Miyazono,et al.  Smad6 inhibits signalling by the TGF-beta superfamily. , 1997, Nature.

[76]  S. Sell,et al.  Environmental Health Perspectives 101(Suppl 5): 15-26 (1993) Cellular Origin of Cancer: Dedifferentiation or Stem Cell Maturation , 2022 .