Accurate Reference Intervals are Required for Accurate Diagnosis and Monitoring of Patients
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Patients’ blood test results are different from one another hence Physicians need a reference measure that they can compare to in order to make the correct clinical decisions. These reference measures, obtained from a sample group in the healthy population, are the “normal ranges” for a specific measure. However normal ranges need to be established only for healthy individuals but also for specific physiologic conditions like pregnancy or ovulation or menopause and some pathologic conditions. The term “normal range” does not cover these conditions. Hence the term “normal range” was given up for the more appropriate term “reference interval”.
[1] P. Hyltoft Petersen,et al. The Nordic Reference Interval Project 2000: recommended reference intervals for 25 common biochemical properties , 2004, Scandinavian journal of clinical and laboratory investigation.
[2] P. S. Horn,et al. A robust approach to reference interval estimation and evaluation. , 1998, Clinical chemistry.
[3] Roberto Colombo,et al. The REALAB project: a new method for the formulation of reference intervals based on current data. , 2005, Clinical chemistry.