SPARC Modulates Cell Growth, Attachment and Migration of U87 Glioma Cells on Brain Extracellular Matrix Proteins

[1]  S. Rempel,et al.  A study of SPARC and vitronectin localization and expression in pediatric and adult gliomas: high SPARC secretion correlates with decreased migration on vitronectin. , 2000, International journal of oncology.

[2]  J. Tonn,et al.  Targeting angiogenesis inhibits tumor infiltration and expression of the pro‐invasive protein SPARC , 2000, International journal of cancer.

[3]  T. Mikkelsen,et al.  Increased SPARC expression promotes U87 glioblastoma invasion in vitro , 1999, International Journal of Developmental Neuroscience.

[4]  E. Sage,et al.  Cell cycle‐dependent nuclear location of the matricellular protein SPARC: Association with the nuclear matrix , 1999, Journal of cellular biochemistry.

[5]  S. Rempel,et al.  SPARC: a potential diagnostic marker of invasive meningiomas. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[6]  J. A. Greenwood,et al.  Signaling of de‐adhesion in cellular regulation and motility , 1998, Microscopy research and technique.

[7]  T. Mikkelsen,et al.  SPARC: a signal of astrocytic neoplastic transformation and reactive response in human primary and xenograft gliomas. , 1998, Journal of neuropathology and experimental neurology.

[8]  E. Sage,et al.  SPARC (BM-40, Osteonectin) Inhibits the Mitogenic Effect of Vascular Endothelial Growth Factor on Microvascular Endothelial Cells* , 1998, The Journal of Biological Chemistry.

[9]  R. Timpl,et al.  Differential modulation of cell adhesion by interaction between adhesive and counter-adhesive proteins: characterization of the binding of vitronectin to osteonectin (BM40, SPARC). , 1997, The Biochemical journal.

[10]  E. Sage,et al.  Regulation of vascular morphogenesis by the matricellular protein SPARC. , 1997, Kidney international.

[11]  M. Westphal,et al.  Glioma invasion in the central nervous system. , 1996, Neurosurgery.

[12]  M. Berens,et al.  Substrates for astrocytoma invasion. , 1995, Neurosurgery.

[13]  J. Wilcox,et al.  Cerebral microenvironment influences expression of the vitronectin gene in astrocytic tumors. , 1995, Journal of cell science.

[14]  M. Folkman,et al.  Inhibition of endothelial cell proliferation by SPARC is mediated through a Ca2+‐binding EF‐hand sequence , 1995, Journal of cellular biochemistry.

[15]  M. Berens,et al.  The role of extracellular matrix in human astrocytoma migration and proliferation studied in a microliter scale assay , 1994, Clinical & Experimental Metastasis.

[16]  M. Berens,et al.  Determinants of human astrocytoma migration. , 1994, Cancer research.

[17]  E. Sage,et al.  The biology of SPARC, a protein that modulates cell‐matrix interactions , 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[18]  E. Sage,et al.  Specific interaction of SPARC with endothelial cells is mediated through a carboxyl-terminal sequence containing a calcium-binding EF hand. , 1993, The Journal of biological chemistry.

[19]  E. Sage,et al.  Differential effects of SPARC and cationic SPARC peptides on DNA synthesis by endothelial cells and fibroblasts , 1993, Journal of cellular physiology.

[20]  R. Ross,et al.  The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[21]  D. Cheresh,et al.  Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells. , 1991, The Journal of clinical investigation.

[22]  R. Timpl,et al.  Calcium-dependent binding of basement membrane protein BM-40 (osteonectin, SPARC) to basement membrane collagen type IV. , 1991, European journal of biochemistry.

[23]  E. Sage,et al.  The Ca2(+)-binding glycoprotein SPARC modulates cell cycle progression in bovine aortic endothelial cells. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[24]  E. Sage,et al.  Functional mapping of SPARC: peptides from two distinct Ca+(+)-binding sites modulate cell shape , 1990, The Journal of cell biology.

[25]  P. Bornstein,et al.  Characterization of a novel serum albumin-binding glycoprotein secreted by endothelial cells in culture. , 1984, The Journal of biological chemistry.

[26]  H. Kleinman,et al.  Osteonectin, a bone-specific protein linking mineral to collagen , 1981, Cell.

[27]  E. Helene Sage Terms of attachment: SPARC and tumorigenesis , 1997 .