Limitations of currently available Chagas disease chemotherapy.

1 Rev Esp Quimioter 2012;25 (1):1-3 post-treatment, which was deemed to reflect the effectiveness of the treatment to clear parasites better than serology. Moreover, PCR allowed treatment failure to be ratified – in our case in 6.9% of the patients, who shifted to positive at the end of the follow-up period. Although PCR is a sensitive and specific tool for the early detection of the parasite’s susceptibility to treatment, a negative PCR result does not necessarily indicate parasitological cure of the patients in the absence of other markers.