TGF-β Promotes Heterogeneity and Drug Resistance in Squamous Cell Carcinoma
暂无分享,去创建一个
[1] V. Lushchak,et al. Glutathione Homeostasis and Functions: Potential Targets for Medical Interventions , 2012, Journal of amino acids.
[2] E. Fuchs,et al. Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia. , 2007, Cancer cell.
[3] K. Kariya,et al. Ectopic coexpression of keratin 8 and 18 promotes invasion of transformed keratinocytes and is induced in patients with cutaneous squamous cell carcinoma. , 2010, Biochemical and biophysical research communications.
[4] Denis Vivien,et al. Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene , 1998, The EMBO journal.
[5] Alejandra Bruna,et al. High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene. , 2007, Cancer cell.
[6] M. Karin,et al. Immunity, Inflammation, and Cancer , 2010, Cell.
[7] P. Chambon,et al. Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling , 2008, Nature.
[8] David R. Kelley,et al. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks , 2012, Nature Protocols.
[9] J. Visvader,et al. Mammary stem cells and the differentiation hierarchy: current status and perspectives , 2014, Genes & development.
[10] H. Moses,et al. Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression. , 2006, Genes & development.
[11] Shankar Srinivas,et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus , 2001, BMC Developmental Biology.
[12] Allan Balmain,et al. TGFβ1 Inhibits the Formation of Benign Skin Tumors, but Enhances Progression to Invasive Spindle Carcinomas in Transgenic Mice , 1996, Cell.
[13] E. Fuchs,et al. Paracrine TGF-β signaling counterbalances BMP-mediated repression in hair follicle stem cell activation. , 2012, Cell stem cell.
[14] A. Berns. Stem Cells for Lung Cancer? , 2005, Cell.
[15] S. Anderson,et al. Integration of Smad and Forkhead Pathways in the Control of Neuroepithelial and Glioblastoma Cell Proliferation , 2004, Cell.
[16] L. Chin,et al. Essential role for oncogenic Ras in tumour maintenance , 1999, Nature.
[17] M. Rentrop,et al. Aberrant expression during two‐stage mouse skin carcinogenesis of a type 147‐kDa keratin, k13, normally associated with terminal differentiation of internal stratified epithelia , 1988, Molecular carcinogenesis.
[18] Roger R. Gomis,et al. C/EBPβ at the core of the TGFβ cytostatic response and its evasion in metastatic breast cancer cells , 2006 .
[19] J. Salk. Clonal evolution in cancer , 2010 .
[20] C. Heldin,et al. Transforming growth factor-β employs HMGA2 to elicit epithelial–mesenchymal transition , 2006, The Journal of cell biology.
[21] J. Massagué. TGFβ signalling in context , 2012, Nature Reviews Molecular Cell Biology.
[22] S. Karlsson,et al. Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable. , 2002, Blood.
[23] David A. Orlando,et al. Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling , 2011, Cell.
[24] J. Massagué,et al. E2F4/5 and p107 as Smad Cofactors Linking the TGFβ Receptor to c-myc Repression , 2002, Cell.
[25] C. Dubois,et al. Skin squamous cell carcinoma propagating cells increase with tumour progression and invasiveness , 2012, The EMBO journal.
[26] L. Kèlland,et al. The resurgence of platinum-based cancer chemotherapy , 2007, Nature Reviews Cancer.
[27] J. Dick,et al. Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity , 2004, Nature Immunology.
[28] C. Corless,et al. Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma. , 2006, Genes & development.
[29] D. Vignali,et al. Design and construction of 2A peptide-linked multicistronic vectors. , 2012, Cold Spring Harbor protocols.
[30] P. Carmeliet,et al. A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours , 2011, Nature.
[31] S. Ghaffari,et al. Stem cells and the impact of ROS signaling , 2014, Development.
[32] E. Fuchs,et al. The harmonies played by TGF-β in stem cell biology. , 2012, Cell stem cell.
[33] J. Massagué,et al. Smad transcription factors. , 2005, Genes & development.
[34] H. Aburatani,et al. Chromatin Immunoprecipitation on Microarray Analysis of Smad2/3 Binding Sites Reveals Roles of ETS1 and TFAP2A in Transforming Growth Factor β Signaling , 2008, Molecular and Cellular Biology.
[35] Gary R. Grotendorst,et al. Production of transforming growth factor beta by human peripheral blood monocytes and neutrophils , 1989, Journal of cellular physiology.
[36] J. Carucci,et al. SOX2 is a cancer-specific regulator of tumor initiating potential in cutaneous squamous cell carcinoma , 2014, Nature Communications.
[37] D. Hanahan,et al. Hallmarks of Cancer: The Next Generation , 2011, Cell.
[38] Frank Bradke,et al. Three-dimensional imaging of solvent-cleared organs using 3DISCO , 2012, Nature Protocols.
[39] Donna D. Zhang,et al. Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response. , 2009, Molecular cell.
[40] Cole Trapnell,et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. , 2010, Nature biotechnology.
[41] A. Krešo,et al. Evolution of the cancer stem cell model. , 2014, Cell stem cell.
[42] T. Mak,et al. Modulation of oxidative stress as an anticancer strategy , 2013, Nature Reviews Drug Discovery.
[43] E. Fuchs,et al. Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling , 2011, Proceedings of the National Academy of Sciences.
[44] R. Derynck,et al. The TGF-β Family , 2008 .
[45] Igor Jurisica,et al. Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment , 2011, Science.
[46] E. Fuchs,et al. Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos , 2010, Nature Medicine.
[47] E. Fuchs,et al. The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[48] S. Rorive,et al. SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma , 2014, Nature.
[49] Kami Kim,et al. Bright and stable near infra-red fluorescent protein for in vivo imaging , 2011, Nature Biotechnology.
[50] Corbin E. Meacham,et al. Tumour heterogeneity and cancer cell plasticity , 2013, Nature.
[51] Irving L. Weissman,et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells , 2009, Nature.