Anti‐obesity effect of feeding probiotic dahi containing Lactobacillus casei NCDC 19 in high fat diet‐induced obese mice

Nowadays, studies about the anti-obesity potential of probiotics are of growing interest. Lactobacilli are one of the well-studied probiotics owing to their preventing effect on metabolic disorders. This study was undertaken to access the anti-obesity effect of probiotic dahi containing Lactobacillus casei NCDC 19 on C57BL/6 mice. Feeding of probiotic dahi showed reduce body weight gain and epididymal fat weights. Moreover, blood glucose, plasma lipids and expression level of leptin were reduced and caecal bifidobacteria counts and adiponectin expression levels were significantly increased. It can be concluded that feeding of probiotic dahi containing L. casei NCDC 19 showed potential anti-obesity effects.

[1]  R. K. Sharma,et al.  Effect of Aloe vera (Aloe barbadensis Miller) on survivability, extent of proteolysis and ACE inhibition of potential probiotic cultures in fermented milk. , 2014, Journal of the science of food and agriculture.

[2]  R. K. Sharma,et al.  A systematic review of Gymnema sylvestre in obesity and diabetes management. , 2014, Journal of the science of food and agriculture.

[3]  F. Jin,et al.  Effects of NS lactobacillus strains on lipid metabolism of rats fed a high-cholesterol diet , 2013, Lipids in Health and Disease.

[4]  D. Pal,et al.  Effect of different preservative treatments on the shelf-life of sorghum malt based fermented milk beverage , 2014, Journal of Food Science and Technology.

[5]  Anil Kumar,et al.  Probiotic Attributes of Lactobacillus rhamnosus of Dairy Origin and Effectiveness of Almond in Stimulation of its Growth in vitro , 2012 .

[6]  V. Schmied,et al.  Moxibustion for cephalic version: a feasibility randomised controlled trial , 2011, BMC complementary and alternative medicine.

[7]  M. Cha,et al.  Antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat diet-induced obese rats , 2011, Lipids in Health and Disease.

[8]  Jun-wen Yang,et al.  Effects of two Lactobacillus strains on lipid metabolism and intestinal microflora in rats fed a high-cholesterol diet , 2011, BMC complementary and alternative medicine.

[9]  Dalong Zhu,et al.  Apocynin Improves Insulin Resistance through Suppressing Inflammation in High-Fat Diet-Induced Obese Mice , 2011, Mediators of inflammation.

[10]  K. Abe,et al.  Antiobesity Effects of Bifidobacterium breve Strain B-3 Supplementation in a Mouse Model with High-Fat Diet-Induced Obesity , 2010, Bioscience, biotechnology, and biochemistry.

[11]  F. Lu,et al.  Effects of four Bifidobacteria on obesity in high-fat diet induced rats. , 2010, World journal of gastroenterology.

[12]  N. Takemura,et al.  Lactobacillus plantarum strain No. 14 reduces adipocyte size in mice fed high-fat diet , 2010, Experimental biology and medicine.

[13]  T. van de Wiele,et al.  Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability , 2009, Gut.

[14]  Jason Chung,et al.  Endoplasmic reticulum stress plays a central role in development of leptin resistance. , 2009, Cell metabolism.

[15]  K. Nagai,et al.  High-fat diet-induced obesity is attenuated by probiotic strain Lactobacillus paracasei ST11 (NCC2461) in rats. , 2008, Obesity research & clinical practice.

[16]  B. B. Jensen,et al.  Early administration of probiotics alters bacterial colonization and limits diet-induced gut dysfunction and severity of necrotizing enterocolitis in preterm pigs. , 2008, The Journal of nutrition.

[17]  Essam M. Hamad,et al.  Effects of milk fermented byLactobacillusgasseri SBT2055 on adipocyte size in rats , 2008, British Journal of Nutrition.

[18]  N. Shah.  Functional cultures and health benefits , 2007 .

[19]  C. Knauf,et al.  Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia , 2007, Diabetologia.

[20]  Saehun Kim,et al.  Effect of dietary inclusion of Lactobacillus acidophilus ATCC 43121 on cholesterol metabolism in rats. , 2007, Journal of microbiology and biotechnology.

[21]  P. Su,et al.  Survival and retention of the probiotic Lactobacillus casei LAFTI® L26 in the gastrointestinal tract of the mouse , 2007, Letters in applied microbiology.

[22]  P. Turnbaugh,et al.  Microbial ecology: Human gut microbes associated with obesity , 2006, Nature.

[23]  S. Kapila,et al.  Antioxidative and hypocholesterolemic effect of Lactobacillus casei ssp casei (biodefensive properties of lactobacilli). , 2006, Indian journal of medical sciences.

[24]  Hui-Young Lee,et al.  Human originated bacteria, Lactobacillus rhamnosus PL60, produce conjugated linoleic acid and show anti-obesity effects in diet-induced obese mice. , 2006, Biochimica et biophysica acta.

[25]  Thomas D. Giles,et al.  Obesity and Cardiovascular Disease: Pathophysiology, Evaluation, and Effect of Weight Loss , 2006, Arteriosclerosis, thrombosis, and vascular biology.

[26]  Folkert Kuipers,et al.  The Farnesoid X Receptor Modulates Adiposity and Peripheral Insulin Sensitivity in Mice* , 2006, Journal of Biological Chemistry.

[27]  Amitabh Sharma,et al.  Mining literature for a comprehensive pathway analysis: A case study for retrieval of homocysteine related genes for genetic and epigenetic studies , 2006, Lipids in Health and Disease.

[28]  M. Heo,et al.  Determinants of leptin gene expression in fat depots of lean mice. , 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

[29]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[30]  Bruce M. Spiegelman,et al.  Obesity and the Regulation of Energy Balance , 2001, Cell.

[31]  A. Bondi,et al.  Effect of vitamin A deficiency on protein catabolism in chicks , 1974, British Journal of Nutrition.

[32]  R. Levy,et al.  Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. , 1972, Clinical chemistry.

[33]  Erich Kunz.  Untersuchungen an normalen und coecektomierten Ratten , 1967 .