Automatic Whole Heart Segmentation Using Deep Learning and Shape Context

To assist 3D cardiac image analysis, we propose an automatic whole heart segmentation using a deep learning framework combined with shape context information that is encoded in volumetric shape models. The proposed processing pipeline consists of three major steps: scout segmentation with orthogonal 2D U-nets, shape context estimation and refining segmentation with U-net and shape context. The proposed method was evaluated using the MMWHS challenge data. Two sets of networks were trained separately for contrast-enhanced CT and MRI. On the 20 training datasets, using 5-fold cross-validation, the average Dice coefficients for the left ventricle, the right ventricle, the left atrium, the right atrium and the myocardium of the left ventricle were 0.895, 0.795, 0.847, 0.821, 0.807 for MRI and 0.935, 0.825, 0.908, 0.881, 0.879 for CT, respectively. Further improvement may be possible given more training data or advanced data augmentation strategy.

[1]  Alistair A. Young,et al.  Atlas-Based Quantification of Cardiac Remodeling Due to Myocardial Infarction , 2014, PloS one.

[2]  Dorin Comaniciu,et al.  Four-Chamber Heart Modeling and Automatic Segmentation for 3-D Cardiac CT Volumes Using Marginal Space Learning and Steerable Features , 2008, IEEE Transactions on Medical Imaging.

[3]  Qian Wang,et al.  Automatic Heart and Vessel Segmentation Using Random Forests and a Local Phase Guided Level Set Method , 2016, RAMBO+HVSMR@MICCAI.

[4]  Örjan Smedby,et al.  Automatic Multi-organ Segmentation in Non-enhanced CT Datasets Using Hierarchical Shape Priors , 2014, 2014 22nd International Conference on Pattern Recognition.

[5]  Thomas Brox,et al.  U-Net: Convolutional Networks for Biomedical Image Segmentation , 2015, MICCAI.

[6]  H. Frimmel,et al.  Fast level-set based image segmentation using coherent propagation. , 2014, Medical physics.

[7]  Daniel Levy,et al.  Lifetime risk of developing coronary heart disease , 1999, The Lancet.

[8]  Zhuowen Tu,et al.  Auto-Context and Its Application to High-Level Vision Tasks and 3D Brain Image Segmentation , 2010, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[9]  Olivier D. Faugeras,et al.  Statistical shape influence in geodesic active contours , 2000, Proceedings IEEE Conference on Computer Vision and Pattern Recognition. CVPR 2000 (Cat. No.PR00662).

[10]  L. Lind,et al.  The Swedish CArdioPulmonary BioImage Study: objectives and design , 2015, Journal of internal medicine.

[11]  Xiahai Zhuang,et al.  Multi-scale patch and multi-modality atlases for whole heart segmentation of MRI , 2016, Medical Image Anal..