The effect of time delay on infection in open long-bone fractures: a 5-year prospective audit from a district general hospital.

OBJECTIVES To determine whether a time delay of greater than 6 h from injury to surgical debridement affected the infection rate in open long-bone fractures in a typical district general hospital in the UK. DESIGN Prospective audit over 5 years. METHODS 142 open long-bone fractures in 130 patients were seen over a 5-year period between 1996 and 2001 in our hospital. 115 fractures in 103 patients were available for study. The data were collected prospectively in weekly audit meetings. Patients were followed until clinical or radiological union occurred or until a secondary procedure for non-union or infection was carried out. RESULTS Surgical debridement was carried out in less than 6 h from injury in 60% of cases and in greater than 6 h from injury in 40% of cases. Infection rates were 10.1% and 10.8%, respectively. CONCLUSIONS We could not demonstrate a significantly increased infection rate in patients in whom surgical debridement occurred greater than 6 h after injury.

[1]  C. A. Jones,et al.  The Effect of Time to Definitive Treatment on the Rate of Nonunion and Infection in Open Fractures , 2002, Journal of orthopaedic trauma.

[2]  D. Seligson,et al.  Adult posttraumatic osteomyelitis of the tibial diaphysis of the tibial shaft. , 1999, Clinical orthopaedics and related research.

[3]  R. Schwartzberg,et al.  A sequential protocol for management of severe open tibial fractures. , 1995, Clinical orthopaedics and related research.

[4]  K. Kindsfater,et al.  Osteomyelitis in Grade II and III Open Tibia Fractures with Late Debridement , 1995, Journal of orthopaedic trauma.

[5]  D. Bednar,et al.  Effect of Time Delay from Injury to Primary Management on the Incidence of Deep Infection After Open Fractures of the Lower Extremities Caused by Blunt Trauma in Adults , 1993, Journal of orthopaedic trauma.

[6]  M. Patzakis,et al.  Factors influencing infection rate in open fracture wounds. , 1989, Clinical orthopaedics and related research.

[7]  Ronald F. Brown Fractures with soft tissue injuries , 1985 .

[8]  R. Gustilo,et al.  OTD classic article review - Gustillo RB, Anderson JT (1976) Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses , 2002, The Journal of bone and joint surgery. American volume.

[9]  J. Harvey,et al.  The role of antibiotics in the management of open fractures. , 1974, The Journal of bone and joint surgery. American volume.