Making Genomic Medicine a Reality

First, I want to express my deep appreciation for the honor of serving as president of our Society and for the opportunity to share some thoughts with you today. For the theme of my address, I propose to ask how genetic advances will impact the practice of medicine over the next decade or two—and what we, as members of the American Society of Human Genetics, should be doing to influence these developments. I will focus on dilemmas that I perceive in prenatal genetics, on population-based genotyping to bring significant changes to the practice of adult medicine (considering both single-gene disorders and more-complex traits), and on the potential to make greater use of family-based genotyping for autosomal dominant disorders.

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