All-in-fiber optofluidic sensor fabricated by femtosecond laser assisted chemical etching.

An all-in-fiber prototype optofluidic device was fabricated by femtosecond laser irradiation and subsequent selective chemical wet etching. Horizontal and vertical microchannels can be flexibly created into an optical fiber to form a fluidic cavity with inlets/outlets. The fluidic cavity also functions as an optical Fabry-Perot cavity in which the filled liquid can be probed. The assembly-free microdevice exhibited a fringe visibility of 20 dB and was demonstrated for measurement of the refractive index of the filling liquids. The proposed all-in-fiber optofluidic micro device is attractive for chemical and biomedical sensing because it is flexible in design, simple to fabricate, mechanically robust, and miniaturized in size.

[1]  Benjamin J. Eggleton,et al.  Compact resonant integrated microfluidic refractometer , 2006 .

[2]  Amardeep Kaur,et al.  High-temperature fiber-optic Fabry-Perot interferometric pressure sensor fabricated by femtosecond laser. , 2013, Optics letters.

[3]  Roberta Ramponi,et al.  Three-dimensional Mach-Zehnder interferometer in a microfluidic chip for spatially-resolved label-free detection. , 2010, Lab on a chip.

[4]  W. Peng,et al.  Novel data processing techniques for dispersive white light interferometer , 2003 .

[5]  Tao Wei,et al.  Fringe Visibility Enhanced Extrinsic Fabry–Perot Interferometer Using a Graded Index Fiber Collimator , 2010, IEEE Photonics Journal.

[6]  D. Psaltis,et al.  Developing optofluidic technology through the fusion of microfluidics and optics , 2006, Nature.

[7]  R. Osellame,et al.  Femtosecond laser microstructuring: an enabling tool for optofluidic lab‐on‐chips , 2011 .

[8]  J. Jensen,et al.  Photonic crystal fiber based evanescent-wave sensor for detection of biomolecules in aqueous solutions , 2003, Conference on Lasers and Electro-Optics, 2003. CLEO '03..

[9]  V. Maselli,et al.  Integration of optical waveguides and microfluidic channels fabricated by femtosecond laser irradiation , 2007, 2007 Conference on Lasers and Electro-Optics (CLEO).

[10]  Hongying Zhu,et al.  Opto-fluidic micro-ring resonator for sensitive label-free viral detection. , 2008, The Analyst.

[11]  Christelle Monat,et al.  Integrated optofluidics: A new river of light , 2007 .

[12]  I Bennion,et al.  Microchannels in conventional single-mode fibers. , 2006, Optics letters.

[13]  Y. Bellouard,et al.  Fabrication of high-aspect ratio, micro-fluidic channels and tunnels using femtosecond laser pulses and chemical etching. , 2004, Optics express.

[14]  Xudong Fan,et al.  Optofluidic Microsystems for Chemical and Biological Analysis. , 2011, Nature photonics.

[15]  A. Woolley,et al.  Ultra-high-speed DNA fragment separations using microfabricated capillary array electrophoresis chips. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[16]  Tao Wei,et al.  Temperature-insensitive miniaturized fiber inline Fabry-Perot interferometer for highly sensitive refractive index measurement. , 2008, Optics express.