Puerarin Ameliorates 3-Nitropropionic Acid-Induced Neurotoxicity in Rats: Possible Neuromodulation and Antioxidant Mechanisms

[1]  Yun-Tai Kim,et al.  Anti-Inflammatory Effects of Total Isoflavones from Pueraria lobata on Cerebral Ischemia in Rats , 2013, Molecules.

[2]  Z. Zuo,et al.  Radix Puerariae: An overview of Its Chemistry, Pharmacology, Pharmacokinetics, and Clinical Use , 2013, Journal of clinical pharmacology.

[3]  Xiaoqun Duan,et al.  Puerarin attenuates neuronal degeneration in the substantia nigra of 6-OHDA-lesioned rats through regulating BDNF expression and activating the Nrf2/ARE signaling pathway , 2013, Brain Research.

[4]  N. Swerdlow Update: Studies of prepulse inhibition of startle, with particular relevance to the pathophysiology or treatment of Tourette Syndrome , 2013, Neuroscience & Biobehavioral Reviews.

[5]  Qiaoling He,et al.  Puerarin attenuates neuronal degeneration and blocks oxidative stress to elicit a neuroprotective effect on substantia nigra injury in 6-OHDA-lesioned rats , 2013, Brain Research.

[6]  M. G. Tadros,et al.  Potential neuroprotective effects of hesperidin on 3-nitropropionic acid-induced neurotoxicity in rats. , 2012, Neurotoxicology.

[7]  Bei Zhang,et al.  Puerarin decreases hypoxia inducible factor-1 alpha in the hippocampus of vascular dementia rats , 2012, Neural regeneration research.

[8]  F. Lin,et al.  Protective Effect of Puerarin on β-Amyloid-Induced Neurotoxicity in Rat Hippocampal Neurons , 2012, Arzneimittelforschung/Drug Research.

[9]  Akram Sidhu,et al.  Peroxisome proliferator-activated receptor-α activation attenuates 3-nitropropionic acid induced behavioral and biochemical alterations in rats: possible neuroprotective mechanisms. , 2012, European journal of pharmacology.

[10]  Jinyan Xie,et al.  Role of puerarin in the signalling of neuropathic pain mediated by P2X3 receptor of dorsal root ganglion neurons , 2012, Brain Research Bulletin.

[11]  M. G. Tadros,et al.  The effect of Ginkgo biloba extract on 3-nitropropionic acid-induced neurotoxicity in rats , 2011, Neurochemistry International.

[12]  C. Chen Mitochondrial dysfunction, metabolic deficits, and increased oxidative stress in Huntington's disease. , 2011, Chang Gung medical journal.

[13]  Anil Kumar,et al.  Possible nitric oxide modulation in protective effect of FK-506 against 3-nitropropionic acid-induced behavioral, oxidative, neurochemical, and mitochondrial alterations in rat brain , 2010, Drug and chemical toxicology.

[14]  S. Arnold,et al.  Brain region-specific vulnerability of astrocytes in response to 3-nitropropionic acid is mediated by cytochrome c oxidase isoform expression , 2010, Cell and Tissue Research.

[15]  P. L. Puri,et al.  HDACs and sirtuins: targets for new pharmacological interventions in human diseases. , 2010, Pharmacological research.

[16]  S. Montes,et al.  Recovery of Motor Deficit, Cerebellar Serotonin and Lipid Peroxidation Levels in the Cortex of Injured Rats , 2010, Neurochemical Research.

[17]  J. Yeomans,et al.  GABA receptors and prepulse inhibition of acoustic startle in mice and rats , 2010, The European journal of neuroscience.

[18]  Shu Yang,et al.  Puerarin protects dopaminergic neurons against 6-hydroxydopamine neurotoxicity via inhibiting apoptosis and upregulating glial cell line-derived neurotrophic factor in a rat model of Parkinson's disease. , 2010, Planta medica.

[19]  A. Santamaría,et al.  3-Nitropropionic Acid as a Tool to Study the Mechanisms Involved in Huntington’s Disease: Past, Present and Future , 2010, Molecules.

[20]  Anil Kumar,et al.  Protective effect of hesperidin and naringin against 3-nitropropionic acid induced Huntington's like symptoms in rats: Possible role of nitric oxide , 2010, Behavioural Brain Research.

[21]  Anil Kumar,et al.  Huntington’s disease: pathogenesis to animal models , 2010, Pharmacological reports : PR.

[22]  C. Ross,et al.  Huntington disease: pathogenesis, biomarkers, and approaches to experimental therapeutics. , 2009, Parkinsonism & related disorders.

[23]  A. Papp,et al.  Altered Open Field Behavior in Rats Induced by Acute Administration of 3-Nitropropionic Acid: Possible Glutamatergic and Dopaminergic Involvement , 2009, Acta biologica Hungarica.

[24]  R. F. Castilho,et al.  3‐nitropropionic acid‐induced mitochondrial permeability transition: Comparative study of mitochondria from different tissues and brain regions , 2009, Journal of neuroscience research.

[25]  P. Garris,et al.  In vivo dopamine release and uptake impairments in rats treated with 3-nitropropionic acid , 2009, Neuroscience.

[26]  Feng Yan,et al.  Puerarin protects against ischemic brain injury in a rat model of transient focal ischemia , 2009, Neurological research.

[27]  J. Finlay,et al.  Extracellular dopamine and norepinephrine in the developing rat prefrontal cortex: Transient effects of early partial loss of dopamine , 2009, Brain Research Bulletin.

[28]  A. Santamaría,et al.  [Model of Huntington's disease induced with 3-nitropropionic acid]. , 2009, Revista de neurologia.

[29]  D. Klimis-Zacas,et al.  Effect of a polyphenol-rich wild blueberry extract on cognitive performance of mice, brain antioxidant markers and acetylcholinesterase activity , 2009, Behavioural Brain Research.

[30]  Gwendolyn R. Goss,et al.  Theory and Practice of Histological Techniques , 2009 .

[31]  J. Sheu,et al.  Neuroprotective mechanisms of puerarin in middle cerebral artery occlusion-induced brain infarction in rats , 2009, Journal of Biomedical Science.

[32]  E. Holmes,et al.  Metabonomic Characterization of the 3-Nitropropionic Acid Rat Model of Huntington’s Disease , 2009, Neurochemical Research.

[33]  Gao Li,et al.  Protecting mechanism of puerarin on the brain neurocyte of rat in acute local ischemia brain injury and local cerebral ischemia-reperfusion injury. , 2008, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[34]  A. Rego,et al.  Mechanisms of neurodegeneration in Huntington’s disease , 2008, European Journal of Neuroscience.

[35]  H. Cui,et al.  [Protective effects of 3'-methoxy-puerarin on rat brain suffering from ischemia]. , 2008, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[36]  K. Chopra,et al.  Protective effect of minocycline, a semi-synthetic second-generation tetracycline against 3-nitropropionic acid (3-NP)-induced neurotoxicity. , 2008, Toxicology.

[37]  T. Nabeshima,et al.  Neural Circuits Containing Pallidotegmental GABAergic Neurons are Involved in the Prepulse Inhibition of the Startle Reflex in Mice , 2007, Biological Psychiatry.

[38]  S. Leung,et al.  Puerarin, an isoflavonoid derived from Radix puerariae, potentiates endothelium-independent relaxation via the cyclic AMP pathway in porcine coronary artery. , 2006, European journal of pharmacology.

[39]  A. Amato,et al.  Effects of L‐Carnitine Pretreatment in Methamphetamine and 3‐Nitropropionic Acid‐Induced Neurotoxicity , 2006, Annals of the New York Academy of Sciences.

[40]  E. Berry,et al.  3-Nitropropionic Acid Is a Suicide Inhibitor of Mitochondrial Respiration That, upon Oxidation by Complex II, Forms a Covalent Adduct with a Catalytic Base Arginine in the Active Site of the Enzyme* , 2005, Journal of Biological Chemistry.

[41]  A. Abdel-Naim,et al.  Neuroprotective effect of taurine in 3-nitropropionic acid-induced experimental animal model of Huntington's disease phenotype , 2005, Pharmacology Biochemistry and Behavior.

[42]  Xiaoxiang Zheng,et al.  The Neuroprotection of puerarin against cerebral ischemia is associated with the prevention of apoptosis in rats. , 2005, Planta medica.

[43]  Liansheng Liu,et al.  Oral uridine pro-drug PN401 decreases neurodegeneration, behavioral impairment, weight loss and mortality in the 3-nitropropionic acid mitochondrial toxin model of Huntington's disease , 2003, Brain Research.

[44]  M. Verbeek,et al.  3-Nitropropionic acid induces cell death and mitochondrial dysfunction in rat corticostriatal slice cultures , 2002, Neuroscience Letters.

[45]  K. I. Maynard,et al.  Acute administration of Ginkgo biloba extract (EGb 761) affords neuroprotection against permanent and transient focal cerebral ischemia in Sprague‐Dawley rats , 2002, Journal of neuroscience research.

[46]  M. Kleven,et al.  Depletion of 5-HT Disrupts Prepulse Inhibition in Rats: Dependence on the Magnitude of Depletion, and Reversal by a 5-HT Precursor , 2002, Neuropsychopharmacology.

[47]  M. van den Buuse,et al.  Estrogen increases prepulse inhibition of acoustic startle in rats. , 2001, European journal of pharmacology.

[48]  N. Swerdlow,et al.  Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies , 2001, Psychopharmacology.

[49]  N. Swerdlow,et al.  Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges , 2001, Psychopharmacology.

[50]  P. Fletcher,et al.  Reduced Brain Serotonin Activity Disrupts Prepulse Inhibition of the Acoustic Startle Reflex: Effects of 5,7-dihydroxytryptamine and p-chlorophenylalanine , 2001, Neuropsychopharmacology.

[51]  M. Pallàs,et al.  Orphenadrine prevents 3‐nitropropionic acid‐induced neurotoxicity in vitro and in vivo , 2001, British journal of pharmacology.

[52]  R. Seaman Effects of acute systemic 3-nitropropionic acid administration on rat activity and acoustic startle , 2000, Neuroscience Letters.

[53]  O. Andreassen,et al.  Mice Deficient in Cellular Glutathione Peroxidase Show Increased Vulnerability to Malonate, 3-Nitropropionic Acid, and 1-Methyl-4-Phenyl-1,2,5,6-Tetrahydropyridine , 2000, The Journal of Neuroscience.

[54]  Verbeek,et al.  3‐Nitropropionic acid induces a spectrum of Huntington’s disease‐like neuropathology in rat striatum , 1999, Neuropathology and applied neurobiology.

[55]  Françoise Condé,et al.  Replicating Huntington's disease phenotype in experimental animals , 1999, Progress in Neurobiology.

[56]  A. Scallet,et al.  3-Nitropropionic Acid (3-NPA) Produces Hypothermia and Inhibits Histochemical Labeling of Succinate Dehydrogenase (SDH) in Rat Brain , 1999, Metabolic Brain Disease.

[57]  B. Vallee,et al.  Daidzin and its antidipsotropic analogs inhibit serotonin and dopamine metabolism in isolated mitochondria. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[58]  N. Swerdlow,et al.  Mitochondrial toxin 3-nitropropionic acid produces startle reflex abnormalities and striatal damage in rats that model some features of Huntington's disease , 1997, Neuroscience Letters.

[59]  Jane S. Paulsen,et al.  Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease. , 1995, Journal of neurology, neurosurgery, and psychiatry.

[60]  B. Hyman,et al.  Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[61]  A. Ludolph,et al.  3-Nitropropionic Acid - Exogenous Animal Neurotoxin and Possible Human Striatal Toxin , 1991, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[62]  M. Uchiyama,et al.  Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. , 1978, Analytical biochemistry.

[63]  D. Segal,et al.  Behavioral activation of rats during intraventricular infusion of norepinephrine. , 1970, Proceedings of the National Academy of Sciences of the United States of America.

[64]  W. Valentine,et al.  Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. , 1967, The Journal of laboratory and clinical medicine.

[65]  G. Ellman,et al.  Tissue sulfhydryl groups. , 1959, Archives of biochemistry and biophysics.

[66]  Han-dong Wang,et al.  Puerarin ameliorates oxidative stress in a rodent model of traumatic brain injury. , 2014, The Journal of surgical research.

[67]  D. Fuchs,et al.  Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation. , 2010, Clinical laboratory.

[68]  A. Papp,et al.  The acute effects of 3-nitropropionic acid on the behavior and spontaneous cortical electrical activity of rats. , 2006, Acta neurobiologiae experimentalis.

[69]  P. Boguszewski,et al.  Bicuculline administration into ventromedial hypothalamus: effects on fear and regional brain monoamines and GABA concentrations in rats. , 2000, Acta neurobiologiae experimentalis.

[70]  J. Coyle An animal model for Huntington's disease. , 1979, Biological psychiatry.