Depression, Anxiety, and Quality of Life in Paroxysmal Kinesigenic Dyskinesia Patients

introDuCtion Paroxysmal kinesigenic dyskinesia (PKD; MIM: 128200) is a movement disorder characterized by transient and recurrent dystonic or choreoathetoid attacks mainly triggered by sudden voluntary movements.[1] PKD is commonly a familial disease in an autosomal dominant mode of inheritance. Three episodic kinesigenic dyskinesia (EKD) loci have been identified in PKD and are defined as Depression, Anxiety, and Quality of Life in Paroxysmal Kinesigenic Dyskinesia Patients

[1]  F. Benfenati,et al.  A novel topology of proline-rich transmembrane protein 2 (PRRT2): Hints for an intracellular function at the synapse. , 2018, The Journal of Biological Chemistry.

[2]  Yung-Yang Lin,et al.  Abnormal Somatosensory Synchronization in Patients With Paroxysmal Kinesigenic Dyskinesia: A Magnetoencephalographic Study , 2017, Clinical EEG and neuroscience.

[3]  F. Benfenati,et al.  PRRT2: from Paroxysmal Disorders to Regulation of Synaptic Function , 2016, Trends in Neurosciences.

[4]  Hong-Xia Wang,et al.  Mutation Analysis of MR-1, SLC2A1, and CLCN1 in 28 PRRT2-negative Paroxysmal Kinesigenic Dyskinesia Patients , 2016, Chinese medical journal.

[5]  F. Benfenati,et al.  PRRT2 Is a Key Component of the Ca2+-Dependent Neurotransmitter Release Machinery , 2016, Cell reports.

[6]  C. Klein,et al.  The evolving spectrum of PRRT2-associated paroxysmal diseases. , 2015, Brain : a journal of neurology.

[7]  B. Tang,et al.  Paroxysmal kinesigenic dyskinesia , 2015, Neurology.

[8]  E. Aydınlar,et al.  The relationships between migraine, depression, anxiety, stress, and sleep disturbances , 2015, Acta Neurologica Belgica.

[9]  Liang Li,et al.  An alternative therapy for drug‐resistant epilepsy: transcutaneous auricular vagus nerve stimulation , 2014, Chinese medical journal.

[10]  K. Y. Zhang,et al.  Psychopathological profile of women with breast cancer based on the symptom checklist-90-R. , 2013, Asian Pacific journal of cancer prevention : APJCP.

[11]  Yung-Yang Lin,et al.  Altered inhibitory modulation of somatosensory cortices in paroxysmal kinesigenic dyskinesia , 2013, Movement disorders : official journal of the Movement Disorder Society.

[12]  Yun-Shien Lee,et al.  Mutations of proline‐rich transmembrane protein‐2 and paroxysmal kinesigenic dyskinesia in Taiwan , 2013, Movement disorders : official journal of the Movement Disorder Society.

[13]  Yung-Yang Lin,et al.  Reduced postmovement cortical inhibition in patients with paroxysmal kinesigenic dyskinesia , 2013, Neurology.

[14]  M. Vidailhet,et al.  PRRT2 mutations and paroxysmal disorders , 2013, European journal of neurology.

[15]  L. Dibbens,et al.  Role of PRRT2 in common paroxysmal neurological disorders: a gene with remarkable pleiotropy , 2013, Journal of Medical Genetics.

[16]  C. Gerloff,et al.  PRRT2-related disorders: further PKD and ICCA cases and review of the literature , 2013, Journal of Neurology.

[17]  Ying Sun,et al.  Somatosensory disinhibition in patients with paroxysmal kinesigenic dyskinesia. , 2012, Chinese medical journal.

[18]  Ning Wang,et al.  Exome sequencing identifies truncating mutations in PRRT2 that cause paroxysmal kinesigenic dyskinesia , 2011, Nature Genetics.

[19]  K. Xia,et al.  Identification of PRRT2 as the causative gene of paroxysmal kinesigenic dyskinesias , 2011, Brain : a journal of neurology.

[20]  Christian E. Elger,et al.  Depression in epilepsy: a critical review from a clinical perspective , 2011, Nature Reviews Neurology.

[21]  M. Hallett,et al.  Clinical evaluation of idiopathic paroxysmal kinesigenic dyskinesia , 2004, Neurology.

[22]  J. Szaflarski,et al.  Seizure disorders, depression, and health-related quality of life , 2004, Epilepsy & Behavior.

[23]  M. Holi,et al.  Assessment of psychiatric symptoms using the SCL-90 , 2003 .

[24]  Raj Sheth,et al.  Comorbid Psychiatric Symptoms in Temporal Lobe Epilepsy: Association with Chronicity of Epilepsy and Impact on Quality of Life , 2000, Epilepsy & Behavior.

[25]  W W Zung,et al.  A rating instrument for anxiety disorders. , 1971, Psychosomatics.

[26]  J. Sareen,et al.  The relationship between migraine and mental disorders in a population-based sample. , 2009, General hospital psychiatry.

[27]  Fanc Ji-qia The introduce and usage of WHOQOL instrument in chinese , 2000 .

[28]  S. Saxena,et al.  The World Health Organization Quality of Life Assessment (WHOQOL): development and general psychometric properties. , 1998, Social science & medicine.

[29]  W. Zung A SELF-RATING DEPRESSION SCALE. , 1965, Archives of general psychiatry.