We assessed information needs about HIV/AIDS and sexually transmitted infections (STI) in the Eastern Mediterranean Region by surveying a sample of people considered knowledgeable about the subject. Respondents felt that information on certain areas of HIV/AIDS/STIs was much needed. Health care workers were perceived to see a high need for information and services generally. Religious and community leaders were perceived to see less need for some information and services (such as condom promotion, sex education for young people). All groups were perceived to see a need for education and services for people living with AIDS and drug users. Television and radio were considered the best channels for health education while training was seen as the most effective method for information exchange.