论文信息 - Toward Age-related Macular Degeneration (AMD) Big Data: Hardware and software design and implementation

Toward Age-related Macular Degeneration (AMD) Big Data: Hardware and software design and implementation

This paper presents a novel Age-related Macular Degeneration (AMD) Big Data platform for future pharmaceutical applications. This platform is a network collecting AMD data from a large number of AMD patients in a central unit for data analytical purposes. Each network node is connected to a headset with graphical interface system for measuring the progression of AMD. Herein we discuss the proposed hardware and software and demonstrate the results for Big Data applications. Based on these results, the proposed platform offers unique and promising advantages for early detection of AMD and for future optimization of in-development AMD related drugs using the obtained Big Data.

Navid Mohaghegh | Ebrahim Ghafar-Zadeh | Sebastian Magierowski | Samal Munidasa

[1] Navid Mohaghegh,et al. Wearable diagnostic system for age-related macular degeneration , 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[2] R. Montés-Micó,et al. Comparison between the preferential hyperacuity perimeter and the Amsler grid to detect age-related macular degeneration and Stargardt's disease , 2011 .

[3] Wensong Zhang. Linux Virtual Server for Scalable Network Services , 2000 .

[4] Gary Rubin,et al. The Amsler chart: absence of evidence is not evidence of absence , 2007, British Journal of Ophthalmology.

[5] P. Fitts. The information capacity of the human motor system in controlling the amplitude of movement. , 1954, Journal of experimental psychology.

[6] Benita J. O’Colmain,et al. Prevalence of age-related macular degeneration in the United States. , 2004, Archives of ophthalmology.

[7] Joseph C. Besharse,et al. The retina and its disorders , 2011 .

[8] M AMSLER,et al. Earliest Symptoms of Diseases of the Macula *† , 1953, The British journal of ophthalmology.

[9] M. Ávila,et al. Comparison of the original Amsler grid with the preferential hyperacuity perimeter for detecting choroidal neovascularization in age-related macular degeneration. , 2007, Arquivos brasileiros de oftalmologia.