A clinically relevant model of focal embolic cerebral ischemia by thrombus and thrombolysis in rhesus monkeys

[1]  X. Ji,et al.  Selective therapeutic cooling: To maximize benefits and minimize side effects related to hypothermia , 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[2]  Jianhong Wang,et al.  A pilot behavioural and neuroimaging investigation on photothrombotic stroke models in rhesus monkeys , 2021, Journal of Neuroscience Methods.

[3]  H. Urbach,et al.  Selective intra-carotid blood cooling in acute ischemic stroke: A safety and feasibility study in an ovine stroke model , 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[4]  Yi Ding,et al.  An MD2-perturbing peptide has therapeutic effects in rodent and rhesus monkey models of stroke , 2021, Science Translational Medicine.

[5]  M. Fisher.  Endovascular Therapy for Basilar-Artery Occlusion - Still Waiting for Answers. , 2021, The New England journal of medicine.

[6]  M. Tymianski,et al.  Plasmin-resistant PSD-95 inhibitors resolve effect-modifying drug-drug interactions between alteplase and nerinetide in acute stroke , 2021, Science Translational Medicine.

[7]  P. Walczak,et al.  White matter demyelination predates axonal injury after ischemic stroke in cynomolgus monkeys , 2021, Experimental Neurology.

[8]  S. Saito,et al.  Biodegradable polymer sirolimus-eluting stents versus durable polymer everolimus-eluting stents in patients undergoing percutaneous coronary intervention: a meta-analysis of individual patient data from five randomized trials. , 2021, American Heart Journal.

[9]  K. Fouad,et al.  New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases , 2021, Frontiers in Aging Neuroscience.

[10]  Lawrence Buja,et al.  Pilot Study of Endovascular Delivery of Mesenchymal Stromal Cells in the Aortic Wall in a Pig Model , 2021, Cell transplantation.

[11]  S. Stice,et al.  Magnetic Resonance Imaging and Gait Analysis Indicate Similar Outcomes Between Yucatan and Landrace Porcine Ischemic Stroke Models , 2021, Frontiers in Neurology.

[12]  M. Wainwright,et al.  Childhood Stroke: Thinking Locally, Acting Globally? , 2020, Stroke.

[13]  Á. Chamorro,et al.  The future of neuroprotection in stroke , 2020, Journal of Neurology, Neurosurgery, and Psychiatry.

[14]  D. Liebeskind,et al.  Correction to: Thrombectomy for Distal, Medium Vessel Occlusions: A Consensus Statement on Present Knowledge and Promising Directions. , 2020, Stroke.

[15]  Youngjeon Lee,et al.  Assessment of Hand Motor Function in a Non-human Primate Model of Ischemic Stroke , 2020, Experimental neurobiology.

[16]  P. Kan,et al.  Canine Model for Selective and Superselective Cerebral Intra-Arterial Therapy Testing , 2020, Neurointervention.

[17]  X. Ji,et al.  Reperfusion plus Selective Intra-arterial Cooling (SI-AC) Improve Recovery in a Nonhuman Primate Model of Stroke , 2020, Neurotherapeutics.

[18]  X. Ji,et al.  Novel Acute Retinal Artery Ischemia and Reperfusion Model in Nonhuman Primates , 2020, Stroke.

[19]  Chunhua Chen,et al.  Intranasal salvinorin A improves neurological outcome in rhesus monkey ischemic stroke model using autologous blood clot , 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[20]  S. Aoki,et al.  Transient Global Amnesia: A Diffusion and Perfusion MRI study , 2020, Journal of neuroimaging : official journal of the American Society of Neuroimaging.

[21]  E. Sena,et al.  Quality and validity of large animal experiments in stroke: A systematic review , 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[22]  M. Jayaraman,et al.  Optimization of Endovascular Therapy in the Neuroangiography Suite to Achieve Fast and Complete (Expanded Treatment in Cerebral Ischemia 2c-3) Reperfusion , 2020, Stroke.

[23]  N. Costes,et al.  A non-human primate model of stroke reproducing endovascular thrombectomy and allowing long-term imaging and neurological read-outs , 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[24]  X. Ji,et al.  Primate Version of Modified Rankin Scale for Classifying Dysfunction in Rhesus Monkeys , 2020, Stroke.

[25]  Feng Yan,et al.  Selective intra-arterial brain cooling improves long-term outcomes in a non-human primate model of embolic stroke: Efficacy depending on reperfusion status , 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[26]  Thalia Shoshana Field,et al.  Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial. , 2020, The Lancet.

[27]  D. Hutmacher,et al.  A preclinical large-animal model for the assessment of critical-size load-bearing bone defect reconstruction , 2020, Nature Protocols.

[28]  F. West,et al.  Large animal ischemic stroke models: replicating human stroke pathophysiology , 2020, Neural regeneration research.

[29]  Joseph Y. Nashed,et al.  Poly-Arginine Peptide-18 (R18) Reduces Brain Injury and Improves Functional Outcomes in a Nonhuman Primate Stroke Model , 2019, Neurotherapeutics.

[30]  Correction to: Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. , 2019, Stroke.

[31]  W. Powers,et al.  Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. , 2019, Stroke.

[32]  E. Lo,et al.  Opening the time window , 2019, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[33]  R. Swanson,et al.  Cofilin-actin rod formation in experimental stroke is attenuated by therapeutic hypothermia and overexpression of the inducible 70 kD inducible heat shock protein (Hsp70) , 2019, Brain circulation.

[34]  N. Henninger,et al.  Infarct Evolution in a Large Animal Model of Middle Cerebral Artery Occlusion , 2019, Translational Stroke Research.

[35]  J. Boltze,et al.  Cell therapy for ischemic stroke: Are differences in preclinical and clinical study design responsible for the translational loss of efficacy? , 2019, Annals of neurology.

[36]  Min Lou,et al.  Influence of occlusion site and baseline ischemic core on outcome in patients with ischemic stroke , 2019, Neurology.

[37]  J. Boltze,et al.  Large animals in neurointerventional research: A systematic review on models, techniques and their application in endovascular procedures for stroke, aneurysms and vascular malformations , 2019, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[38]  R. Leak,et al.  A new era for stroke therapy: Integrating neurovascular protection with optimal reperfusion , 2018, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[39]  R. Vink,et al.  Large animal models of stroke and traumatic brain injury as translational tools. , 2018, American journal of physiology. Regulatory, integrative and comparative physiology.

[40]  John D Harding,et al.  Nonhuman Primates and Translational Research: Progress, Opportunities, and Challenges. , 2017, ILAR journal.

[41]  A. Jadhav,et al.  Assessing the efficacy of endovascular therapy in stroke treatments: updates from the new generation of trials , 2017, Expert review of cardiovascular therapy.

[42]  A. Buchan,et al.  Neuroprotection in stroke: the importance of collaboration and reproducibility , 2017, Brain : a journal of neurology.

[43]  J. Kaldor,et al.  A multicentre double-blind randomised controlled trial evaluating the efficacy of daily use of antibacterial mouthwash against oropharyngeal gonorrhoea among men who have sex with men: the OMEGA (Oral Mouthwash use to Eradicate GonorrhoeA) study protocol , 2017, BMC Infectious Diseases.

[44]  K. Jeong,et al.  Sustained diffusion reversal with in-bore reperfusion in monkey stroke models: Confirmed by prospective magnetic resonance imaging , 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[45]  Jianhong Wang,et al.  A pilot study on transient ischemic stroke induced with endothelin-1 in the rhesus monkeys , 2017, Scientific Reports.

[46]  C. Sommer.  Ischemic stroke: experimental models and reality , 2017, Acta Neuropathologica.

[47]  Ann M Stowe,et al.  Control of cerebral ischemia with magnetic nanoparticles , 2016, Nature Methods.

[48]  X. Ji,et al.  Endovascular Ischemic Stroke Models in Nonhuman Primates , 2017, Neurotherapeutics.

[49]  J. McCarrey,et al.  Advantages of nonhuman primates as preclinical models for evaluating stem cell-based therapies for Parkinson's disease. , 2016, Stem cell research.

[50]  Feng Yan,et al.  Endovascular ischemic stroke models of adult rhesus monkeys: a comparison of two endovascular methods , 2016, Scientific Reports.

[51]  M. Chopp,et al.  Neural Stem Cells and Ischemic Brain , 2016, Journal of stroke.

[52]  A. Demchuk,et al.  Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials , 2016, The Lancet.

[53]  G. Steinberg,et al.  Impaired Arm Function and Finger Dexterity in a Nonhuman Primate Model of Stroke: Motor and Cognitive Assessments , 2016, Stroke.

[54]  Shery Jacob,et al.  A simple practice guide for dose conversion between animals and human , 2016, Journal of basic and clinical pharmacy.

[55]  G. deVeber,et al.  Severe Cerebral Vasospasm and Childhood Arterial Ischemic Stroke After Intrathecal Cytarabine , 2016, Pediatrics.

[56]  Mark D. Huffman,et al.  Heart Disease and Stroke Statistics—2016 Update: A Report From the American Heart Association , 2016, Circulation.

[57]  Lloyd H. Michael,et al.  The Guide for the Care and Use of Laboratory Animals. , 2016, ILAR journal.

[58]  H. D'Arceuil,et al.  Magnetic resonance imaging-based cerebral tissue classification reveals distinct spatiotemporal patterns of changes after stroke in non-human primates , 2015, BMC Neuroscience.

[59]  S. Zola,et al.  An Enhanced Model of Middle Cerebral Artery Occlusion in Nonhuman Primates Using an Endovascular Trapping Technique , 2015, American Journal of Neuroradiology.

[60]  M. Fisher,et al.  Future directions of acute ischaemic stroke therapy , 2015, The Lancet Neurology.

[61]  M. Chopp,et al.  Focal embolic cerebral ischemia in the rat , 2015, Nature Protocols.

[62]  S. Zola,et al.  Temporal Evolution of Ischemic Lesions in Nonhuman Primates: A Diffusion and Perfusion MRI Study , 2015, PloS one.

[63]  Hester F. Lingsma,et al.  A randomized trial of intraarterial treatment for acute ischemic stroke. , 2015, The New England journal of medicine.

[64]  Chao Dang,et al.  An ischemic stroke model of nonhuman primates for remote lesion studies: a behavioral and neuroimaging investigation. , 2015, Restorative neurology and neuroscience.

[65]  F. Sharp,et al.  Improving the translation of animal ischemic stroke studies to humans , 2015, Metabolic Brain Disease.

[66]  Hongjun Li,et al.  A more consistent intraluminal rhesus monkey model of ischemic stroke , 2014, Neural regeneration research.

[67]  E. Suzuki,et al.  SMTP-7, a Novel Small-Molecule Thrombolytic for Ischemic Stroke: A Study in Rodents and Primates , 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[68]  Michela Ponzio,et al.  Endovascular treatment for acute ischemic stroke. , 2013, The New England journal of medicine.

[69]  P. Lyden,et al.  Journal of Neuroscience Methods , 2013 .

[70]  Andreas Meisel,et al.  Do stroke models model stroke? , 2012, Disease Models & Mechanisms.

[71]  D. J. Cook,et al.  A Translational Paradigm for the Preclinical Evaluation of the Stroke Neuroprotectant Tat-NR2B9c in Gyrencephalic Nonhuman Primates , 2012, Science Translational Medicine.

[72]  D. J. Cook,et al.  Nonhuman Primate Models of Stroke for Translational Neuroprotection Research , 2012, Neurotherapeutics.

[73]  D. J. Cook,et al.  Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain , 2012, Nature.

[74]  D. Vivien,et al.  Thrombotic Stroke in the Anesthetized Monkey (Macaca mulatta): Characterization by MRI – A Pilot Study , 2012, Cerebrovascular Diseases.

[75]  E. Mohammadi,et al.  Barriers and facilitators related to the implementation of a physiological track and trigger system: A systematic review of the qualitative evidence , 2017, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[76]  P. Chan,et al.  Analysis of glucose metabolism in cynomolgus monkeys during aging , 2012, Biogerontology.

[77]  M. Chopp,et al.  Erythropoietin in Combination of Tissue Plasminogen Activator Exacerbates Brain Hemorrhage When Treatment Is Initiated 6 Hours After Stroke , 2010, Stroke.

[78]  Myriam Bernaudin,et al.  Permanent or Transient Chronic Ischemic Stroke in the Non-Human Primate: Behavioral, Neuroimaging, Histological, and Immunohistochemical Investigations , 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[79]  Marc Fisher,et al.  Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations , 2009, Stroke.

[80]  C. Mărgăritescu,et al.  Histopathological changes in acute ischemic stroke. , 2009, Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie.

[81]  H. Iwao,et al.  Ginsenoside Rb1 reduces neurodegeneration in the peri-infarct area of a thromboembolic stroke model in non-human primates. , 2008, Journal of pharmacological sciences.

[82]  David A Boas,et al.  Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia. , 2007, Brain : a journal of neurology.

[83]  R. Gonzalez,et al.  Serial Diffusion Tensor MRI After Transient and Permanent Cerebral Ischemia in Nonhuman Primates , 2007, Stroke.

[84]  Vincent M. Vacca,et al.  Acute ischemic stroke. , 2006, Nursing.

[85]  H. D'Arceuil,et al.  Middle cerebral artery occlusion in Macaca fascicularis: acute and chronic stroke evolution , 2006, Journal of medical primatology.

[86]  G. Donnan,et al.  1,026 Experimental treatments in acute stroke , 2006, Annals of neurology.

[87]  Tetsuya Yoshikawa,et al.  Effects of intra-arterial urokinase on a non-human primate thromboembolic stroke model. , 2006, Journal of pharmacological sciences.

[88]  R. Gonzalez,et al.  Acute studies of a new primate model of reversible middle cerebral artery occlusion. , 2005, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

[89]  A. Ringer,et al.  Intraarterial reteplase and intravenous abciximab for treatment of acute ischemic stroke , 2005, Neuroradiology.

[90]  L. D Hall,et al.  Serial MRI, functional recovery, and long-term infarct maturation in a non-human primate model of stroke , 2003, Brain Research Bulletin.

[91]  R. Higashida,et al.  Trial Design and Reporting Standards for Intra-Arterial Cerebral Thrombolysis for Acute Ischemic Stroke , 2003, Stroke.

[92]  J. Kordower,et al.  Chronic ischemic stroke model in cynomolgus monkeys: Behavioral, neuroimaging and anatomical study , 2003, Neurological research.

[93]  G. D. del Zoppo,et al.  Models of focal cerebral ischemia in the nonhuman primate. , 2003, ILAR journal.

[94]  M. Chopp,et al.  Adjuvant Treatment With Neuroserpin Increases the Therapeutic Window for Tissue-Type Plasminogen Activator Administration in a Rat Model of Embolic Stroke , 2002, Circulation.

[95]  K Minematsu,et al.  Serial Changes in Cerebral Blood Flow and Flow—Metabolism Uncoupling in Primates with Acute Thromboembolic Stroke , 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[96]  K. Minematsu,et al.  Experimental thromboembolic stroke in cynomolgus monkey , 2001, Journal of Neuroscience Methods.

[97]  R. Ridley,et al.  NXY-059, a Free Radical–Trapping Agent, Substantially Lessens the Functional Disability Resulting From Cerebral Ischemia in a Primate Species , 2001, Stroke.

[98]  S. Nishiyama,et al.  Detection of reperfusion injury using PET in a monkey model of cerebral ischemia. , 2000, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[99]  T. Waltz,et al.  Experimental acute thrombotic stroke in baboons. , 1986, Stroke.

[100]  R. Spetzler,et al.  Acute NMR changes during MCA occlusion: a preliminary study in primates. , 1983, Stroke.

[101]  B. Siesjö,et al.  Thresholds in cerebral ischemia - the ischemic penumbra. , 1981, Stroke.

[102]  M. Dujovny,et al.  Selective Lenticulostriate Occlusion in the Primate , 1981, Stroke.

[103]  C. West,et al.  Experimental Regional Cerebral Ischemia in the Middle Cerebral Artery Territory in Primates Part 1: Angio-Anatomy and Description of an Experimental Model With Selective Embolization of the Internal Carotid Artery Bifurcation , 1977, Stroke.