Benzene metabolites induce the loss and long arm deletion of chromosomes 5 and 7 in human lymphocytes.

[1]  Luoping Zhang,et al.  Induction of chromosome-specific aneuploidy and micronuclei in human lymphocytes by metabolites of 1,3-butadiene. , 1997, Carcinogenesis.

[2]  R. Irons,et al.  The process of leukemogenesis. , 1996, Environmental health perspectives.

[3]  Martyn T. Smith The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia. , 1996, Environmental health perspectives.

[4]  M Dosemeci,et al.  An expanded cohort study of cancer among benzene-exposed workers in China. Benzene Study Group. , 1996, Environmental health perspectives.

[5]  E. Green,et al.  Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases. , 1996, Blood.

[6]  M. Spitz,et al.  Correlation between selected environmental exposures and karyotype in acute myelocytic leukemia. , 1996, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[7]  W. Bodell,et al.  Role of hydrogen peroxide in the formation of DNA adducts in HL-60 cells treated with benzene metabolites. , 1996, Biochemical and biophysical research communications.

[8]  J. Boultwood,et al.  Molecular characterization of the 7q deletion in myeloid disorders , 1996, British journal of haematology.

[9]  J. Pedersen‐Bjergaard,et al.  Different genetic pathways in leukemogenesis for patients presenting with therapy-related myelodysplasia and therapy-related acute myeloid leukemia. , 1995, Blood.

[10]  J. Trent,et al.  Use of fluorescence in situ hybridization (FISH) to study chromosomal damage induced by radiation and bromodeoxyuridine in human colon cancer cells. , 1994, International journal of radiation oncology, biology, physics.

[11]  D. Moore,et al.  On the frequency of chromosome exchanges in a control population measured by chromosome painting. , 1994, Mutation research.

[12]  D. Eastmond,et al.  Detection of hyperdiploidy and chromosome breakage in interphase human lymphocytes following exposure to the benzene metabolite hydroquinone using multicolor fluorescence in situ hybridization with DNA probes. , 1994, Mutation research.

[13]  Luoping Zhang,et al.  Detection of 1,2,4-benzenetriol induced aneuploidy and microtubule disruption by fluorescence in situ hybridization and immunocytochemistry. , 1994, Mutation research.

[14]  R. Espinosa,et al.  Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[15]  D. Eastmond Induction of micronuclei and aneuploidy by the quinone-forming agents benzene and o-phenylphenol. , 1993, Toxicology letters.

[16]  Luoping Zhang,et al.  Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo. , 1993, Cancer research.

[17]  al. et,et al.  Deletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasia , 1993, Science.

[18]  D J Schaid,et al.  Fluorescence in situ hybridization: a sensitive method for trisomy 8 detection in bone marrow specimens. , 1992, Blood.

[19]  J W Gray,et al.  Molecular cytogenetics in human cancer diagnosis , 1992, Cancer.

[20]  F. Mertens,et al.  Cytogenetics of secondary myelodysplasia (sMDS) and acute nonlymphocvtic leukemia (sANLL) , 1991, European journal of haematology.

[21]  D. Eastmond,et al.  Two benzene metabolites, catechol and hydroquinone, produce a synergistic induction of micronuclei and toxicity in cultured human lymphocytes. , 1991, Mutation research.

[22]  D. Smeets,et al.  Interphase cytogenetics of hematological cancer: comparison of classical karyotyping and in situ hybridization using a panel of eleven chromosome specific DNA probes. , 1991, Cancer research.

[23]  F. Ramaekers,et al.  Numerical chromosome 1, 7, 9, and 11 aberrations in bladder cancer detected by in situ hybridization. , 1991, Cancer research.

[24]  B. Dutrillaux,et al.  Chromosome aberrations induced by etoposide (VP‐16) are not random , 1990, International journal of cancer.

[25]  S. Larsen,et al.  Chromosome aberrations and prognostic factors in therapy-related myelodysplasia and acute nonlymphocytic leukemia. , 1990, Blood.

[26]  I. Barrai,et al.  Genotoxicity of two metabolites of benzene: phenol and hydroquinone show strong synergistic effects in vivo. , 1990, Mutation research.

[27]  Martyn T. Smith,et al.  Characterization of micronuclei induced in human lymphocytes by benzene metabolites. , 1990, Cancer research.

[28]  D. Eastmond,et al.  Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity. , 1989, Environmental health perspectives.

[29]  M. Ikeda,et al.  Determination of catechol and quinol in the urine of workers exposed to benzene. , 1988, British journal of industrial medicine.

[30]  A. Kligerman,et al.  Sister chromatid exchange induction in human lymphocytes exposed to benzene and its metabolites in vitro. , 1985, Cancer research.

[31]  P. Nilsson,et al.  Chromosome pattern, occupation, and clinical features in patients with acute nonlymphocytic leukemia. , 1981, Cancer genetics and cytogenetics.

[32]  R D Irons,et al.  Inhibition of lymphocyte transformation and microtubule assembly by quinone metabolites of benzene: evidence for a common mechanism. , 1981, Journal of the Reticuloendothelial Society.

[33]  J. Rowley,et al.  Nonrandom chromosomal abnormalities in acute nonlymphocytic leukemia in patients treated for Hodgkin disease and non-Hodgkin lymphomas , 1977 .

[34]  S. Ellard,et al.  Use of multicolour chromosome painting to identify chromosomal rearrangements in human lymphocytes exposed to bleomycin: A comparison with conventional cytogenetic analysis of giemsa‐stained chromosomes , 1995, Environmental and molecular mutagenesis.

[35]  Luoping Zhang,et al.  Benzene metabolite, 1,2,4‐benzenetriol, induces micronuclei and oxidative DNA damage in human lymphocytes and HL60 cells , 1993, Environmental and molecular mutagenesis.

[36]  T. Hastie,et al.  Statistical Models in S , 1991 .

[37]  B. Dutrillaux,et al.  The chemotherapeutic drug melphalan induces breakage of chromosomes regions rearranged in secondary leukemia. , 1989, Cancer genetics and cytogenetics.

[38]  J. Rowley,et al.  Correlation of occupation and karyotype in adults with acute nonlymphocytic leukemia. , 1982, Blood.