Optical microcavity scanning 3D tomography.

A scanning optical microcavity is exploited to achieve lens-free 3D tomography of microfluidic channels. The microcavity, powered by a low-coherence source, is realized by approaching a cleaved fiber to few tens of micrometers over the sample. The interference of scattered waves inside the cavity shapes the transverse field distribution by focusing the beam and overcoming the diffraction limit due to the optical-fiber numerical aperture. The focusing effect is also preserved in the inner layers of the sample, allowing optical 3D tomography. Analysis of microfluidic channels was demonstrated through this noninvasive technique. Although the experimental setup recalls the well-known fiber-optic Fourier-domain common-path optical coherence tomography, the proposed method has intrinsic characteristics that distinguish it from the former one.

[1]  Tullio Rozzi,et al.  Stationary Mode Distribution and Sidewall Roughness Effects in Overmoded Optical Waveguides , 2010, Journal of Lightwave Technology.

[2]  Xinlei Zhou,et al.  Wide-Range Displacement Sensor Based on Fiber-Optic Fabry–Perot Interferometer for Subnanometer Measurement , 2011, IEEE Sensors Journal.

[3]  J. Sharma,et al.  高アスペクト比MEMSデバイス製造のためのSF 6 ,BCl 3 およびArベースの処方を用いるモリブデンエッチング , 2013 .

[4]  K. M. Tan,et al.  In-fiber common-path optical coherence tomography using a conical-tip fiber. , 2009, Optics express.

[5]  Jin U. Kang,et al.  Optimization of an angled fiber probe for common-path optical coherence tomography. , 2013, Optics letters.

[6]  Marco Farina,et al.  Infrared imaging in liquid through an extrinsic optical microcavity. , 2013, Optics letters.

[7]  Roberta Ramponi,et al.  Hybrid chemical etching of femtosecond laser irradiated structures for engineered microfluidic devices , 2013 .

[8]  R. Myllylä,et al.  Evaluation of microfluidic channels with optical coherence tomography , 2010, Laser Applications in Life Sciences.

[9]  Sum Huan Ng,et al.  Investigation of hot roller embossing for microfluidic devices , 2009 .

[10]  Yan Zhang,et al.  Miniature fiber-optic multicavity Fabry-Perot interferometric biosensor. , 2005, Optics letters.

[11]  Jin U. Kang,et al.  Fiber-optic Fourier-domain common-path OCT , 2008 .

[12]  Jin U. Kang,et al.  All-fiber common-path optical coherence tomography: sensitivity optimization and system analysis , 2005, IEEE Journal of Selected Topics in Quantum Electronics.

[13]  Jae Seok Park,et al.  Double common-path interferometer for flexible optical probe of optical coherence tomography , 2012, Optics express.

[14]  K. Vahala Optical microcavities : Photonic technologies , 2003 .

[15]  Marco Farina,et al.  OPTICAL FIBER EXTRINSIC MICRO-CAVITY SCANNING MICROSCOPY , 2013 .

[16]  Jin U. Kang,et al.  Distortion-free freehand-scanning OCT implemented with real-time scanning speed variance correction , 2012, Optics Express.

[17]  Ji-huan Chen,et al.  Extrinsic fiber-optic Fabry-Perot interferometer sensor for refractive index measurement of optical glass. , 2010, Applied optics.