Polycomb group complexes--many combinations, many functions.
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[1] Giacomo Cavalli,et al. Recruitment of Polycomb group complexes and their role in the dynamic regulation of cell fate choice , 2009, Development.
[2] D. Reinberg,et al. Role of the polycomb protein EED in the propagation of repressive histone marks , 2009, Nature.
[3] Robert E. Kingston,et al. Mechanisms of Polycomb gene silencing: knowns and unknowns , 2009, Nature Reviews Molecular Cell Biology.
[4] H. Lipshitz,et al. A Vertebrate Polycomb Response Element Governs Segmentation of the Posterior Hindbrain , 2009, Cell.
[5] Jürg Müller,et al. Essential Role of the Glycosyltransferase Sxc/Ogt in Polycomb Repression , 2009, Science.
[6] Raja Jothi,et al. Genome-Wide uH2A Localization Analysis Highlights Bmi1-Dependent Deposition of the Mark at Repressed Genes , 2009, PLoS genetics.
[7] M. D. Simon,et al. Polycomb Proteins Remain Bound to Chromatin and DNA during DNA Replication In Vitro , 2009, Cell.
[8] Jürg Müller,et al. Biochemical mechanisms of gene regulation by polycomb group protein complexes. , 2009, Current opinion in genetics & development.
[9] Leonie Ringrose,et al. Non-coding RNAs in Polycomb/Trithorax regulation , 2009, RNA biology.
[10] Hana Kim,et al. AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2 , 2009, Nucleic acids research.
[11] Gene W. Yeo,et al. Divergent Transcription from Active Promoters , 2008, Science.
[12] Leighton J. Core,et al. Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters , 2008, Science.
[13] J. Simon,et al. Roles of the EZH2 histone methyltransferase in cancer epigenetics. , 2008, Mutation research.
[14] D. Reinberg,et al. Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms. , 2008, Molecular cell.
[15] Guo-Cheng Yuan,et al. EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. , 2008, Molecular cell.
[16] R. Young,et al. H2AZ Is Enriched at Polycomb Complex Target Genes in ES Cells and Is Necessary for Lineage Commitment , 2008, Cell.
[17] Antoine H. F. M. Peters,et al. Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryos. , 2008, Developmental cell.
[18] Jennifer A. Erwin,et al. Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome , 2008, Science.
[19] T. Kerppola,et al. Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences , 2008, Proceedings of the National Academy of Sciences.
[20] J. Komorowski,et al. Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation. , 2008, Molecular cell.
[21] Juri Rappsilber,et al. A model for transmission of the H3K27me3 epigenetic mark , 2008, Nature Cell Biology.
[22] Jeroen A. A. Demmers,et al. dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing. , 2008, Genes & development.
[23] Simon Kasif,et al. Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains , 2008, PLoS genetics.
[24] K. Helin,et al. Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor , 2008, Molecular and Cellular Biology.
[25] Terry Magnuson,et al. Polycomb Repressive Complex 2 Is Dispensable for Maintenance of Embryonic Stem Cell Pluripotency , 2008, Stem cells.
[26] J. Lees,et al. E2f6 and Bmi1 cooperate in axial skeletal development , 2008, Developmental dynamics : an official publication of the American Association of Anatomists.
[27] O. Ohara,et al. Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity , 2008, Development.
[28] S. Orkin,et al. PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos , 2008, Nature Genetics.
[29] Jie Zhang,et al. MEL-18 Interacts with HSF2 and the SUMO E2 UBC9 to Inhibit HSF2 Sumoylation* , 2008, Journal of Biological Chemistry.
[30] T. Kerppola,et al. Changes in the Distributions and Dynamics of Polycomb Repressive Complexes during Embryonic Stem Cell Differentiation , 2008, Molecular and Cellular Biology.
[31] D. Reinberg,et al. Ezh2 Requires PHF1 To Efficiently Catalyze H3 Lysine 27 Trimethylation In Vivo , 2008, Molecular and Cellular Biology.
[32] H. Stunnenberg,et al. A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. , 2008, Molecular cell.
[33] Hengbin Wang,et al. Role of hPHF1 in H3K27 Methylation and Hox Gene Silencing , 2007, Molecular and Cellular Biology.
[34] Ruchir Shah,et al. RNA polymerase is poised for activation across the genome , 2007, Nature Genetics.
[35] Haruhiko Koseki,et al. Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells , 2007, Nature Cell Biology.
[36] Hengbin Wang,et al. Regulation of cell cycle progression and gene expression by H2A deubiquitination , 2007, Nature.
[37] Min Gyu Lee,et al. Demethylation of H3K27 Regulates Polycomb Recruitment and H2A Ubiquitination , 2007, Science.
[38] N. Brockdorff,et al. A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin. , 2007, Molecular cell.
[39] I. Issaeva,et al. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development , 2007, Nature.
[40] M. Begemann,et al. Concise Review: Roles of Polycomb Group Proteins in Development and Disease: A Stem Cell Perspective , 2007, Stem cells.
[41] C. Allis,et al. Polycomb Group proteins: an evolutionary perspective. , 2007, Trends in genetics : TIG.
[42] H. Stunnenberg,et al. Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes , 2007, The EMBO journal.
[43] C. Glass,et al. A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. , 2007, Molecular cell.
[44] R. Jaenisch,et al. A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells , 2007, Cell.
[45] Howard Y. Chang,et al. Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs , 2007, Cell.
[46] L. Ringrose. Polycomb comes of age: genome-wide profiling of target sites. , 2007, Current opinion in cell biology.
[47] U. Grossniklaus,et al. Polycomb group and trithorax group proteins in Arabidopsis. , 2007, Biochimica et biophysica acta.
[48] Anne H. O'Donnell,et al. Hyperconserved CpG domains underlie Polycomb-binding sites , 2007, Proceedings of the National Academy of Sciences.
[49] K. Helin,et al. Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A‐ARF locus , 2007, The EMBO journal.
[50] S. Henikoff,et al. Histone Replacement Marks the Boundaries of cis-Regulatory Domains , 2007, Science.
[51] Kristian Helin,et al. The Polycomb Group Protein Suz12 Is Required for Embryonic Stem Cell Differentiation , 2007, Molecular and Cellular Biology.
[52] Daniel Chourrout,et al. Genome Regulation by Polycomb and Trithorax Proteins , 2007, Cell.
[53] Peter A. Jones,et al. The Epigenomics of Cancer , 2007, Cell.
[54] M. Atchison,et al. Polycomb recruitment to DNA in vivo by the YY1 REPO domain , 2006, Proceedings of the National Academy of Sciences.
[55] Aaron Ciechanover,et al. The polycomb protein Ring1B generates self atypical mixed ubiquitin chains required for its in vitro histone H2A ligase activity. , 2006, Molecular cell.
[56] Anke Sparmann,et al. Polycomb silencers control cell fate, development and cancer , 2006, Nature Reviews Cancer.
[57] Adone Mohd-Sarip,et al. Architecture of a polycomb nucleoprotein complex. , 2006, Molecular cell.
[58] A. Möller,et al. Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2. , 2006, Molecular cell.
[59] Jürg Müller,et al. Polycomb response elements and targeting of Polycomb group proteins in Drosophila. , 2006, Current opinion in genetics & development.
[60] Yuri B Schwartz,et al. Polycomb Complexes and the Propagation of the Methylation Mark at the Drosophila Ubx Gene* , 2006, Journal of Biological Chemistry.
[61] J. A. Wamstad,et al. Polycomb Group and SCF Ubiquitin Ligases Are Found in a Novel BCOR Complex That Is Recruited to BCL6 Targets , 2006, Molecular and Cellular Biology.
[62] Hengbin Wang,et al. Role of Bmi1 in H2A Ubiquitylation and Hox Gene Silencing* , 2006, Journal of Biological Chemistry.
[63] Jürg Müller,et al. Histone trimethylation and the maintenance of transcriptional ON and OFF states by trxG and PcG proteins. , 2006, Genes & development.
[64] Yi Zhang,et al. Structure of a Bmi-1-Ring1B Polycomb Group Ubiquitin Ligase Complex* , 2006, Journal of Biological Chemistry.
[65] T. Jenuwein,et al. Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing , 2006, The EMBO journal.
[66] M. Vidal,et al. Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8 , 2006, Development.
[67] Oliver Weichenrieder,et al. Structure and E3‐ligase activity of the Ring–Ring complex of Polycomb proteins Bmi1 and Ring1b , 2006, The EMBO journal.
[68] J. Zeitlinger,et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells , 2006, Nature.
[69] Giacomo Cavalli,et al. The role of Polycomb Group Proteins in Cell Cycle Regulation During Development , 2006, Cell cycle.
[70] Malgorzata Schelder,et al. A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities. , 2006, Genes & development.
[71] Kristian Helin,et al. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. , 2006, Genes & development.
[72] Megan F. Cole,et al. Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells , 2006, Cell.
[73] James A. Cuff,et al. A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells , 2006, Cell.
[74] C. Allis,et al. Mouse Polycomb Proteins Bind Differentially to Methylated Histone H3 and RNA and Are Enriched in Facultative Heterochromatin , 2006, Molecular and Cellular Biology.
[75] Richard Bourgon,et al. Genome-wide analysis of Polycomb targets in Drosophila melanogaster , 2006, Nature Genetics.
[76] T. Magnuson,et al. The Polycomb Group Protein EED Is Dispensable for the Initiation of Random X-Chromosome Inactivation , 2006, PLoS genetics.
[77] Samantha A Beck,et al. Polycomb group mutants exhibit mitotic defects in syncytial cell cycles of Drosophila embryos. , 2006, Developmental biology.
[78] B. Panning,et al. The Polycomb group protein Eed protects the inactive X-chromosome from differentiation-induced reactivation , 2006, Nature Cell Biology.
[79] Yi Zhang,et al. Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. , 2005, Molecular cell.
[80] P. Taghavi,et al. Association of BMI1 with Polycomb Bodies Is Dynamic and Requires PRC2/EZH2 and the Maintenance DNA Methyltransferase DNMT1 , 2005, Molecular and Cellular Biology.
[81] Megan F. Cole,et al. Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells , 2005, Cell.
[82] Leah Barrera,et al. A high-resolution map of active promoters in the human genome , 2005, Nature.
[83] R. Heintzmann,et al. Polycomb group protein complexes exchange rapidly in living Drosophila , 2005, Development.
[84] F. Karch,et al. Synergistic recognition of an epigenetic DNA element by Pleiohomeotic and a Polycomb core complex. , 2005, Genes & development.
[85] R. Kingston,et al. Analysis of a Polycomb Group Protein Defines Regions That Link Repressive Activity on Nucleosomal Templates to In Vivo Function , 2005, Molecular and Cellular Biology.
[86] Haruhiko Koseki,et al. Mammalian Polyhomeotic Homologues Phc2 and Phc1 Act in Synergy To Mediate Polycomb Repression of Hox Genes , 2005, Molecular and Cellular Biology.
[87] Dmitri A. Nusinow,et al. Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[88] H. Kawamoto,et al. Polycomb Group Gene mel-18 Regulates Early T Progenitor Expansion by Maintaining the Expression of Hes-1, a Target of the Notch Pathway1 , 2005, The Journal of Immunology.
[89] D. Reinberg,et al. Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[90] E. Li,et al. Ring1b-mediated H2A Ubiquitination Associates with Inactive X Chromosomes and Is Involved in Initiation of X Inactivation* , 2004, Journal of Biological Chemistry.
[91] R. Kingston,et al. Chromatin Compaction by a Polycomb Group Protein Complex , 2004, Science.
[92] M. Atchison,et al. YY1 DNA binding and PcG recruitment requires CtBP. , 2004, Genes & development.
[93] G. Lyons,et al. The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. , 2004, Genes & development.
[94] Haruhiko Koseki,et al. Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. , 2004, Developmental cell.
[95] M. Vidal,et al. Role of histone H2A ubiquitination in Polycomb silencing , 2004, Nature.
[96] Kristian Helin,et al. Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity , 2004, The EMBO journal.
[97] Yi Zhang,et al. Hierarchical recruitment of polycomb group silencing complexes. , 2004, Molecular cell.
[98] T. Kajiume,et al. Polycomb group gene mel-18 modulates the self-renewal activity and cell cycle status of hematopoietic stem cells. , 2004, Experimental hematology.
[99] Paul Tempst,et al. Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3. , 2004, Molecular cell.
[100] Y. Schwartz,et al. Polycomb silencing blocks transcription initiation. , 2004, Molecular cell.
[101] S. Morrison,et al. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation , 2003, Nature.
[102] Jürg Müller,et al. Molecular and genetic analysis of the Polycomb group gene Sex combs extra/Ring in Drosophila , 2003, Mechanisms of Development.
[103] Youngchang Kim,et al. Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. , 2003, Genes & development.
[104] Irving L. Weissman,et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells , 2003, Nature.
[105] N. Brockdorff,et al. Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes. , 2003, Developmental cell.
[106] Hengbin Wang,et al. Role of Histone H3 Lysine 27 Methylation in X Inactivation , 2003, Science.
[107] N. Bonini,et al. Transcription factor YY1 functions as a PcG protein in vivo , 2003, The EMBO journal.
[108] J. Voncken,et al. Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[109] B. Chait,et al. Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement , 2003, Nature Immunology.
[110] D. Reinberg,et al. Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. , 2002, Genes & development.
[111] V. Pirrotta,et al. Drosophila Enhancer of Zeste/ESC Complexes Have a Histone H3 Methyltransferase Activity that Marks Chromosomal Polycomb Sites , 2002, Cell.
[112] Brigitte Wild,et al. Histone Methyltransferase Activity of a Drosophila Polycomb Group Repressor Complex , 2002, Cell.
[113] P. Pandolfi,et al. Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling. , 2002, Developmental cell.
[114] Hengbin Wang,et al. Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing , 2002, Science.
[115] M. Vidal,et al. Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice. , 2002, Development.
[116] N. Brockdorff,et al. Mitotically Stable Association of Polycomb Group Proteins Eed and Enx1 with the Inactive X Chromosome in Trophoblast Stem Cells , 2002, Current Biology.
[117] David M. Livingston,et al. A Complex with Chromatin Modifiers That Occupies E2F- and Myc-Responsive Genes in G0 Cells , 2002, Science.
[118] T. Magnuson,et al. Cell and tissue requirements for the gene eed during mouse gastrulation and organogenesis , 2001, Genesis.
[119] R. Kingston,et al. Reconstitution of a functional core polycomb repressive complex. , 2001, Molecular cell.
[120] T. Magnuson,et al. Imprinted X inactivation maintained by a mouse Polycomb group gene , 2001, Nature Genetics.
[121] T. Kitamura,et al. Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene. , 2001, Immunity.
[122] M. Surani,et al. The Polycomb-Group GeneEzh2 Is Required for Early Mouse Development , 2001, Molecular and Cellular Biology.
[123] M. Vidal,et al. Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression. , 2001, Development.
[124] A. Otte,et al. The Polycomb Group Protein EED Interacts with YY1, and Both Proteins Induce Neural Tissue in XenopusEmbryos , 2001, Molecular and Cellular Biology.
[125] M. Vidal,et al. Loss- and gain-of-function mutations show a polycomb group function for Ring1A in mice. , 2000, Development.
[126] P. Freemont,et al. HPC3 Is a New Human Polycomb Orthologue That Interacts and Associates with RING1 and Bmi1 and Has Transcriptional Repression Properties* , 2000, The Journal of Biological Chemistry.
[127] J. Voncken,et al. Chromatin-association of the Polycomb group protein BMI1 is cell cycle-regulated and correlates with its phosphorylation status. , 1999, Journal of cell science.
[128] U. Thorsteinsdóttir,et al. Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation. , 1999, Genes & development.
[129] R. Kingston,et al. Stabilization of Chromatin Structure by PRC1, a Polycomb Complex , 1999, Cell.
[130] N. Schork,et al. The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo. , 1998, Development.
[131] T. Tokuhisa,et al. mel-18 negatively regulates cell cycle progression upon B cell antigen receptor stimulation through a cascade leading to c-myc/cdc25. , 1998, Immunity.
[132] Mark J Alkema,et al. Genetic interactions and dosage effects of Polycomb group genes in mice. , 1998, Development.
[133] P. Freemont,et al. The Human Polycomb Group Complex Associates with Pericentromeric Heterochromatin to Form a Novel Nuclear Domain , 1998, The Journal of cell biology.
[134] Y. Katoh-Fukui,et al. Male-to-female sex reversal in M33 mutant mice , 1998, Nature.
[135] M. Whiteley,et al. The Drosophila Polycomb group gene pleiohomeotic encodes a DNA binding protein with homology to the transcription factor YY1. , 1998, Molecular cell.
[136] H. Strutt,et al. The Distribution of Polycomb-Group Proteins During Cell Division and Development in Drosophila Embryos: Impact on Models for Silencing , 1998, The Journal of cell biology.
[137] Mark J Alkema,et al. MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex. , 1997, Journal of molecular biology.
[138] M. A. Motaleb,et al. Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects. , 1997, Development.
[139] R van Driel,et al. RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor , 1997, Molecular and cellular biology.
[140] M. Aurrand-Lions,et al. Altered cellular proliferation and mesoderm patterning in Polycomb-M33-deficient mice. , 1997, Development.
[141] Mark J Alkema,et al. The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression , 1996, Mechanisms of Development.
[142] R. Balling,et al. A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton. , 1996, Development.
[143] A. Ishida,et al. mel‐18, a Polycomb group‐related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity. , 1995, The EMBO journal.
[144] T. Magnuson,et al. The eed mutation disrupts anterior mesoderm production in mice. , 1995, Development.
[145] M. Sofroniew,et al. Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. , 1994, Genes & development.
[146] R. Paro,et al. Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster. , 1992, Genes & development.
[147] E. Lewis. A gene complex controlling segmentation in Drosophila , 1978, Nature.
[148] R. Jaenisch,et al. UvA-DARE ( Digital Academic Repository ) Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive , 2017 .
[149] Hideki Ohdan,et al. Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation. , 2008, Genes & development.
[150] Vincenzo Pirrotta,et al. Polycomb silencing mechanisms and the management of genomic programmes , 2007, Nature Reviews Genetics.
[151] T. Misteli,et al. Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. , 2006, Developmental cell.
[152] D. Beach,et al. Polycomb CBX7 has a unifying role in cellular lifespan , 2004, Nature Cell Biology.
[153] V. Orlando,et al. Drosophila chromosome condensation proteins Topoisomerase II and Barren colocalize with Polycomb and maintain Fab-7 PRE silencing. , 2001, Molecular cell.