A Recognition Method of Lung Nodule Shadows in X-Ray CT Images Using 3D Object Models

In this paper, we describe a recognition method of lung nodule shadows in X-ray CT images using 3-dimensional nodule and blood vessel models. From these 3D object models, artificial CT images are generated as templates. The templates are then applied to input images which comprise of suspicious shadows. If any parameters of the suspicious shadow matches a nodule template rather than any blood vessel template, then it is determined to be abnormal. Otherwise, it is determined to be normal. By applying our new method to the actual lung CT images of 38 patients, the false positive ratio is reduced to 4.31 [shadow/patient] with the sensitivity exceeding 95%.

[1]  Satoshi Morita,et al.  Psychosocial domain in quality of life as an independent prognostic factor for survival and tumor response in patients with advanced non-small cell lung cancer (NSCLS) , 2000 .

[2]  Shinji Yamamoto,et al.  Image processing for computer-aided diagnosis of lung cancer by CT (LSCT) , 1994, Systems and Computers in Japan.

[3]  Scott D. Roth,et al.  Ray casting for modeling solids , 1982, Comput. Graph. Image Process..

[4]  VincentL. Morphological grayscale reconstruction in image analysis , 1993 .

[5]  Shinji Yamamoto,et al.  Quoit filter-a new filter based on mathematical morphology to extract the isolated shadow, and its application to automatic detection of lung cancer in X-ray CT , 1996, Proceedings of 13th International Conference on Pattern Recognition.

[6]  Luc Vincent,et al.  Morphological grayscale reconstruction in image analysis: applications and efficient algorithms , 1993, IEEE Trans. Image Process..

[7]  Hirotsugu Takabatake,et al.  Development of a computer-aided detection system for lung cancer diagnosis , 1992, Medical Imaging.

[8]  Masayuki Murakami,et al.  Computerized detection of malignant tumors on digital mammograms , 1999, IEEE Transactions on Medical Imaging.

[9]  Xinhua Zhuang,et al.  Image Analysis Using Mathematical Morphology , 1987, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[10]  Noboru Niki,et al.  A CAD system for lung cancer based on CT image , 2001, CARS.

[11]  Hao Jiang,et al.  A CAD system for lung cancer screening test by X-ray CT , 2001, CARS.

[12]  Hiroshi Fujita,et al.  Automated detection of pulmonary nodules in helical CT images based on an improved template-matching technique , 2001, IEEE Transactions on Medical Imaging.