Challenges and opportunities for brainstem neuroimaging with ultrahigh field MRI

[1]  Kevin Murphy,et al.  Mapping the MRI voxel volume in which thermal noise matches physiological noise—Implications for fMRI , 2007, NeuroImage.

[2]  Richard E. Harris,et al.  Brain correlates of phasic autonomic response to acupuncture stimulation: An event‐related fMRI study , 2013, Human brain mapping.

[3]  N. Tzourio-Mazoyer,et al.  Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain , 2002, NeuroImage.

[4]  S. Mori,et al.  White matter atlases based on diffusion tensor imaging , 2009, Current opinion in neurology.

[5]  R. Wise Drug-activation of brain reward pathways. , 1998, Drug and alcohol dependence.

[6]  Lawrence L. Wald,et al.  A 32‐channel combined RF and B0 shim array for 3T brain imaging , 2016, Magnetic resonance in medicine.

[7]  J. Hornung,et al.  The human raphe nuclei and the serotonergic system , 2003, Journal of Chemical Neuroanatomy.

[8]  Howard L Fields,et al.  Isolating the Modulatory Effect of Expectation on Pain Transmission: A Functional Magnetic Resonance Imaging Study , 2006, The Journal of Neuroscience.

[9]  Ralf Deichmann,et al.  fMRI of the brainstem using dual-echo EPI , 2011, NeuroImage.

[10]  Jiangyang Zhang,et al.  Feasibility of creating a high-resolution 3D diffusion tensor imaging based atlas of the human brainstem: A case study at 11.7T , 2013, NeuroImage.

[11]  M. Tosetti,et al.  MR imaging of the substantia nigra at 7 T enables diagnosis of Parkinson disease. , 2014, Radiology.

[12]  M. Zhuo,et al.  Biphasic modulation of spinal nociceptive transmission from the medullary raphe nuclei in the rat. , 1997, Journal of neurophysiology.

[13]  Uzay E. Emir,et al.  Elevated Pontine and Putamenal GABA Levels in Mild-Moderate Parkinson Disease Detected by 7 Tesla Proton MRS , 2012, PloS one.

[14]  J. Ellrich,et al.  Non-invasive Access to the Vagus Nerve Central Projections via Electrical Stimulation of the External Ear: fMRI Evidence in Humans , 2015, Brain Stimulation.

[15]  D. Rothman,et al.  Dynamic multi-coil shimming of the human brain at 7 T. , 2011, Journal of magnetic resonance.

[16]  P. Guyenet,et al.  Baro-activated neurons with pulse-modulated activity in the rat caudal ventrolateral medulla express GAD67 mRNA. , 2003, Journal of neurophysiology.

[17]  Trong-Kha Truong,et al.  Integrated RF/shim coil array for parallel reception and localized B 0 shimming in the human brain , 2014, NeuroImage.

[18]  R. Yezierski Spinomesencephalic tract: Projections from the lumbosacral spinal cord of the rat, cat, and monkey , 1988, The Journal of comparative neurology.

[19]  Cyril Poupon,et al.  7 tesla magnetic resonance imaging: A closer look at substantia nigra anatomy in Parkinson's disease , 2014, Movement disorders : official journal of the Movement Disorder Society.

[20]  Claus Lamm,et al.  Comparing neural response to painful electrical stimulation with functional MRI at 3 and 7T , 2013, NeuroImage.

[21]  Antoine Lutti,et al.  Multiparametric brainstem segmentation using a modified multivariate mixture of Gaussians☆ , 2013, NeuroImage: Clinical.

[22]  David Borsook,et al.  Neuroimaging of the periaqueductal gray: State of the field , 2012, NeuroImage.

[23]  R. Gruetter,et al.  Methodology of1H NMR spectroscopy of the human brain at very high magnetic fields , 2005, Applied magnetic resonance.

[24]  Nikos K. Logothetis,et al.  fMRI at High Spatial Resolution: Implications for BOLD-Models , 2016, Front. Comput. Neurosci..

[25]  J. Tomasch,et al.  The human nucleus ambiguus. A quantitative study , 1961, The Anatomical record.

[26]  Essa Yacoub,et al.  In Vivo 7T MRI of the Non-Human Primate Brainstem , 2015, PloS one.

[27]  Lawrence L. Wald,et al.  Automatic cortical surface reconstruction of high-resolution T 1 echo planar imaging data , 2016, NeuroImage.

[28]  A. Dale,et al.  Functional Analysis of V3A and Related Areas in Human Visual Cortex , 1997, The Journal of Neuroscience.

[29]  M. Heinricher,et al.  The Brainstem and Nociceptive Modulation , 2020, The Senses: A Comprehensive Reference.

[30]  G H Glover,et al.  Image‐based method for retrospective correction of physiological motion effects in fMRI: RETROICOR , 2000, Magnetic resonance in medicine.

[31]  Paul M. Matthews,et al.  Connectivity-based segmentation of the substantia nigra in human and its implications in Parkinson's disease , 2010, NeuroImage.

[32]  Y. Shavit,et al.  Intrinsic mechanisms of pain inhibition: activation by stress. , 1984, Science.

[33]  Arthur W. Toga,et al.  Stereotaxic white matter atlas based on diffusion tensor imaging in an ICBM template , 2008, NeuroImage.

[34]  S. Kollias,et al.  Duvernoy's Atlas of the Human Brain Stem and Cerebellum , 2009 .

[35]  Florian Beissner,et al.  Advances in functional magnetic resonance imaging of the human brainstem , 2014, NeuroImage.

[36]  G. Glover,et al.  Physiological noise in oxygenation‐sensitive magnetic resonance imaging , 2001, Magnetic resonance in medicine.

[37]  K. Fuxe,et al.  EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS. , 1964, Acta physiologica Scandinavica. Supplementum.

[38]  Robert Turner,et al.  High-Resolution MR Imaging of the Human Brainstem In vivo at 7 Tesla , 2013, Front. Hum. Neurosci..

[39]  Ethan S. Bromberg-Martin,et al.  Dopamine in Motivational Control: Rewarding, Aversive, and Alerting , 2010, Neuron.

[40]  V. Arango,et al.  Morphometry of the dorsal raphe nucleus serotonergic neurons in suicide victims , 1999, Biological Psychiatry.

[41]  A I Basbaum,et al.  Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. , 1984, Annual review of neuroscience.

[42]  F. Beissner,et al.  Investigating the Human Brainstem with Structural and Functional MRI , 2014, Front. Hum. Neurosci..

[43]  Anja K. E. Horn,et al.  Olszewski and Baxter's cytoarchitecture of the human brainstem , 2014 .

[44]  Xavier Golay,et al.  Accelerated parallel imaging for functional imaging of the human brain , 2006, NMR in biomedicine.

[45]  Siegfried Trattnig,et al.  A study-specific fMRI normalization approach that operates directly on high resolution functional EPI data at 7Tesla , 2014, NeuroImage.

[46]  F. Beissner,et al.  Functional MRI of the Brainstem: Common Problems and their Solutions , 2015, Clinical Neuroradiology.

[47]  R. Bowtell,et al.  Visualization of nigrosome 1 and its loss in PD , 2013, Neurology.

[48]  Y. Cheng,et al.  Susceptibility mapping as a means to visualize veins and quantify oxygen saturation , 2010, Journal of magnetic resonance imaging : JMRI.

[49]  Mark Jenkinson,et al.  Functional subdivision of the human periaqueductal grey in respiratory control using 7 tesla fMRI , 2015, NeuroImage.

[50]  Jonathan D. Cohen,et al.  An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance. , 2005, Annual review of neuroscience.

[51]  Anders M. Dale,et al.  Automatic parcellation of human cortical gyri and sulci using standard anatomical nomenclature , 2010, NeuroImage.

[52]  O. Petroff,et al.  Book Review: GABA and Glutamate in the Human Brain , 2002 .

[53]  K. Browning,et al.  Brainstem circuits regulating gastric function. , 2006, Annual review of physiology.

[54]  Alberto Prats-Galino,et al.  Functional anatomy of subcortical circuits issuing from or integrating at the human brainstem , 2012, Clinical Neurophysiology.

[55]  N. Hadjikhani,et al.  Altered functional magnetic resonance imaging resting‐state connectivity in periaqueductal gray networks in migraine , 2011, Annals of neurology.

[56]  Stefan Skare,et al.  How to correct susceptibility distortions in spin-echo echo-planar images: application to diffusion tensor imaging , 2003, NeuroImage.

[57]  A. Basbaum,et al.  The peptidergic organization of the cat periaqueductal gray. II. The distribution of immunoreactive substance P and vasoactive intestinal polypeptide , 1983, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[58]  Martin A. Lindquist,et al.  Modeling the hemodynamic response function in fMRI: Efficiency, bias and mis-modeling , 2009, NeuroImage.

[59]  P. Luppi,et al.  Brainstem mechanisms of paradoxical (REM) sleep generation , 2011, Pflügers Archiv - European Journal of Physiology.

[60]  Klaus Seppi,et al.  Visualization of nigrosome 1 and its loss in PD: Pathoanatomical correlation and in vivo 7T MRI , 2014, Neurology.

[61]  M Skalej,et al.  Patterns of age-related shrinkage in cerebellum and brainstem observed in vivo using three-dimensional MRI volumetry. , 1999, Cerebral cortex.

[62]  Torsten Rohlfing,et al.  MRI estimates of brain iron concentration in normal aging using quantitative susceptibility mapping , 2011, NeuroImage.

[63]  Catie Chang,et al.  Brain–heart interactions: challenges and opportunities with functional magnetic resonance imaging at ultra-high field , 2016, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[64]  Andreas Straube,et al.  Treatment of chronic migraine with transcutaneous stimulation of the auricular branch of the vagal nerve (auricular t-VNS): a randomized, monocentric clinical trial , 2015, The Journal of Headache and Pain.

[65]  A. Parent,et al.  Dopaminergic innervation of the basal ganglia in the squirrel monkey as revealed by tyrosine hydroxylase immunohistochemistry , 1989, The Journal of comparative neurology.

[66]  John C Gore,et al.  Localized high-resolution DTI of the human midbrain using single-shot EPI, parallel imaging, and outer-volume suppression at 7T. , 2013, Magnetic resonance imaging.

[67]  Eun-Jung Choi,et al.  Glucose metabolism of the midline nuclei raphe in the brainstem observed by PET–MRI fusion imaging , 2012, NeuroImage.

[68]  G. Adriany,et al.  Regional Neurochemical Profiles in the Non-human Primate Model by 1H MRS at 7T , 2012 .

[69]  Rebecca Elliott,et al.  Affective Cognition and its Disruption in Mood Disorders , 2011, Neuropsychopharmacology.

[70]  S. Sara,et al.  Network reset: a simplified overarching theory of locus coeruleus noradrenaline function , 2005, Trends in Neurosciences.

[71]  Tipu Z. Aziz,et al.  A spatiotemporal analysis of gait freezing and the impact of pedunculopontine nucleus stimulation , 2012, Brain : a journal of neurology.

[72]  D. Mendelowitz,et al.  Stimulation of NTS activates NMDA and non-NMDA receptors in rat cardiac vagal neurons in the nucleus ambiguus , 1998, Brain Research.

[73]  Qasim Aziz,et al.  A Comparison of Visceral and Somatic Pain Processing in the Human Brainstem Using Functional Magnetic Resonance Imaging , 2005, The Journal of Neuroscience.

[74]  Z. Cho,et al.  Seven‐tesla magnetic resonance images of the substantia nigra in Parkinson disease , 2012, Annals of neurology.

[75]  Jeong-Hee Kim,et al.  Individually differentiated serotonergic raphe nuclei measured with brain PET/MR imaging. , 2014, Radiology.

[76]  Luke A Henderson,et al.  Real‐time imaging of the medullary circuitry involved in the generation of spontaneous muscle sympathetic nerve activity in awake subjects , 2009, Human brain mapping.

[77]  E. G. Ventureyra,et al.  Transcutaneous vagus nerve stimulation for partial onset seizure therapy , 2000, Child's Nervous System.

[78]  F. Bloom,et al.  ACTIVITY OF NOREPINEPHRINE-CONTAINING LOCUS COERULEUS NEURONS IN THE UNANESTHETIZED SQUIRREL MONKEY , 1979 .

[79]  J. Ciriello,et al.  Collateral axonal projections from hypothalamic hypocretin neurons to cardiovascular sites in nucleus ambiguus and nucleus tractus solitarius , 2003, Brain Research.

[80]  Eduardo E. Benarroch,et al.  Periaqueductal gray , 2012, Neurology.

[81]  H. Fields,et al.  Putative nociceptive modulatory neurons in the dorsolateral pontomesencephalic reticular formation , 1989, Brain Research.

[82]  Lawrence L. Wald,et al.  Comparison of physiological noise at 1.5 T, 3 T and 7 T and optimization of fMRI acquisition parameters , 2005, NeuroImage.

[83]  Florian Beissner,et al.  MICA—A toolbox for masked independent component analysis of fMRI data , 2016, Human brain mapping.

[84]  H. Critchley Neural mechanisms of autonomic, affective, and cognitive integration , 2005, The Journal of comparative neurology.

[85]  K. Uğurbil,et al.  In vivo 1H NMR spectroscopy of the human brain at high magnetic fields: Metabolite quantification at 4T vs. 7T , 2009, Magnetic resonance in medicine.

[86]  P. Hobson,et al.  Accuracy of diagnosis in patients with presumed Parkinson's disease. , 1999, Age and ageing.

[87]  F. Bloom,et al.  Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[88]  J. Hughes,et al.  Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. , 1992, Journal of neurology, neurosurgery, and psychiatry.

[89]  P. Sah,et al.  Where and what is the PPN and what is its role in locomotion? , 2015, Brain : a journal of neurology.

[90]  V. Napadow,et al.  Evoked pain analgesia in chronic pelvic pain patients using respiratory-gated auricular vagal afferent nerve stimulation. , 2012, Pain medicine.

[91]  D. Naritoku,et al.  The effect of vagus nerve stimulation on migraines. , 2003, The journal of pain : official journal of the American Pain Society.

[92]  I. Hentall,et al.  The activity of neurons in the rostral medulla of the rat during withdrawal from noxious heat , 1983, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[93]  Kamil Ugurbil,et al.  Noninvasive quantification of human brain ascorbate concentration using 1H NMR spectroscopy at 7 T , 2010, NMR in biomedicine.

[94]  A. Basbaum,et al.  The peptidergic organization of the cat periaqueductal gray. I. The distribution of immunoreactive enkephalin-containing neurons and terminals , 1983, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[95]  Paul S. Morgan,et al.  In vivo mapping of the human locus coeruleus , 2009, NeuroImage.

[96]  A. Parent,et al.  Carpenter's Human Neuroanatomy , 1996 .

[97]  J. Salamone,et al.  The Mysterious Motivational Functions of Mesolimbic Dopamine , 2012, Neuron.

[98]  P. Kara,et al.  Neural correlates of single vessel hemodynamic responses in vivo , 2016, Nature.

[99]  C. Heckman,et al.  Active properties of motoneurone dendrites: diffuse descending neuromodulation, focused local inhibition , 2008, The Journal of physiology.

[100]  T. Erkinjuntti,et al.  The normal brain stem from infancy to old age , 1994, Neuroradiology.

[101]  A. Graybiel The basal ganglia , 1995, Trends in Neurosciences.

[102]  P. Riederer,et al.  Time course of nigrostriatal degeneration in parkinson's disease , 1976, Journal of Neural Transmission.

[103]  M. Mesulam,et al.  Atlas of cholinergic neurons in the forebrain and upper brainstem of the macaque based on monoclonal choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry , 1984, Neuroscience.

[104]  Max C. Keuken,et al.  Quantifying inter-individual anatomical variability in the subcortex using 7T structural MRI , 2014, NeuroImage.

[105]  Wade K. Smith,et al.  The human locus coeruleus: computer reconstruction of cellular distribution , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[106]  C. Morris,et al.  Histochemical distribution of non-haem iron in the human brain. , 1992, Acta anatomica.

[107]  Robert Turner,et al.  Recent applications of UHF‐MRI in the study of human brain function and structure: a review , 2016, NMR in biomedicine.

[108]  Mark D'Esposito,et al.  Variation of BOLD hemodynamic responses across subjects and brain regions and their effects on statistical analyses , 2004, NeuroImage.

[109]  M. Hariz,et al.  Stereotactic localization of the human pedunculopontine nucleus: atlas-based coordinates and validation of a magnetic resonance imaging protocol for direct localization. , 2008, Brain : a journal of neurology.

[110]  R. Edelman,et al.  Resolution enhancement in single‐shot imaging using simultaneous acquisition of spatial harmonics (SMASH) , 1999, Magnetic resonance in medicine.

[111]  H. Fields,et al.  Nucleus raphe magnus inhibition of spinal cord dorsal horn neurons , 1977, Brain Research.

[112]  M. Kalia Neuroanatomical organization of the respiratory centers. , 1977, Federation proceedings.

[113]  E. Esposito,et al.  Serotonin modulation of the basal ganglia circuitry: therapeutic implication for Parkinson's disease and other motor disorders. , 2008, Progress in brain research.

[114]  S. Lehéricy,et al.  Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease. , 2010, The Journal of clinical investigation.

[115]  B R Rosen,et al.  Mr contrast due to intravascular magnetic susceptibility perturbations , 1995, Magnetic resonance in medicine.

[116]  D. Lima,et al.  The medullary dorsal reticular nucleus as a pronociceptive centre of the pain control system , 2002, Progress in Neurobiology.

[117]  J. Hobson,et al.  Sleep cycle control and cholinergic mechanisms: Differential effects of carbachol injections at pontine brain stem sites , 1975, Brain Research.

[118]  Yasuo Terayama,et al.  Neuromelanin magnetic resonance imaging of locus ceruleus and substantia nigra in Parkinson's disease , 2006, Neuroreport.

[119]  K. Davis,et al.  Intrinsic functional connectivity of periaqueductal gray subregions in humans , 2016, Human brain mapping.

[120]  F. Calamante,et al.  Pictorial review of in vivo human brain: from anatomy to molecular imaging. , 2014, World neurosurgery.

[121]  Y. Hosobuchi,et al.  Pain relief by electrical stimulation of the central gray matter in humans and its reversal by naloxone. , 1977, Science.

[122]  A I Basbaum,et al.  Brainstem control of spinal pain-transmission neurons. , 1978, Annual review of physiology.

[123]  B. Lumb,et al.  Separation of A- versus C-nociceptive inputs into spinal–brainstem circuits , 2008, Neuroscience.

[124]  C. Berridge,et al.  The locus coeruleus–noradrenergic system: modulation of behavioral state and state-dependent cognitive processes , 2003, Brain Research Reviews.

[125]  Gülin Öz,et al.  Regional neurochemical profiles in the human brain measured by 1H MRS at 7 T using local B1 shimming , 2012, NMR in biomedicine.

[126]  B. Fahy Intraoperative and perioperative complications with a vagus nerve stimulation device. , 2010, Journal of clinical anesthesia.

[127]  Richard Bandler,et al.  Central circuits mediating patterned autonomic activity during active vs. passive emotional coping , 2000, Brain Research Bulletin.

[128]  R. Bowtell,et al.  Increase in the iron content of the substantia nigra and red nucleus in multiple sclerosis and clinically isolated syndrome: A 7 Tesla MRI study , 2015, Journal of magnetic resonance imaging : JMRI.

[129]  V. Napadow,et al.  (395) Brainstem activity and connectivity is modulated by respiratory-gated auricular vagus afferent nerve stimulation (RAVANS) in migraine patients - an fMRI study. , 2016, The journal of pain : official journal of the American Pain Society.

[130]  D. Mendelowitz,et al.  Respiratory modulation of premotor cardiac vagal neurons in the brainstem , 2010, Respiratory Physiology & Neurobiology.

[131]  Ronald G. García,et al.  Reduced insula habituation associated with amplification of trigeminal brainstem input in migraine , 2017, Cephalalgia : an international journal of headache.

[132]  L. Becerra,et al.  Altered Hypothalamic Functional Connectivity with Autonomic Circuits and the Locus Coeruleus in Migraine , 2014, PloS one.

[133]  G. Halliday,et al.  Cytoarchitecture of serotonin‐synthesizing neurons in the pontine tegmentum of the human brain , 1991, Synapse.

[134]  George Paxinos,et al.  Atlas of the human brainstem , 1995 .

[135]  C. Peck,et al.  Differential brain activity in subjects with painful trigeminal neuropathy and painful temporomandibular disorder , 2014, PAIN®.

[136]  B. Meldrum,et al.  Glutamate as a neurotransmitter in the brain: review of physiology and pathology. , 2000, The Journal of nutrition.

[137]  Gary Aston-Jones,et al.  Designer receptor manipulations reveal a role of the locus coeruleus noradrenergic system in isoflurane general anesthesia , 2014, Proceedings of the National Academy of Sciences.

[138]  Mark Jenkinson,et al.  Conditioned respiratory threat in the subdivisions of the human periaqueductal gray , 2016, eLife.

[139]  G. Koob,et al.  Drug Addiction, Dysregulation of Reward, and Allostasis , 2001, Neuropsychopharmacology.

[140]  Anders M. Dale,et al.  An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest , 2006, NeuroImage.

[141]  M. D’Esposito,et al.  The Variability of Human, BOLD Hemodynamic Responses , 1998, NeuroImage.

[142]  Olivia K. Faull,et al.  Physiological Noise in Brainstem fMRI , 2013, Front. Hum. Neurosci..

[143]  Karl J. Friston,et al.  Analysis of fMRI Time-Series Revisited—Again , 1995, NeuroImage.

[144]  J. Monti The structure of the dorsal raphe nucleus and its relevance to the regulation of sleep and wakefulness. , 2010, Sleep medicine reviews.

[145]  N. Mizuno,et al.  Central distribution of primary afferent fibers in the Arnold's nerve (the auricular branch of the vagus nerve): A transganglionic HRP study in the cat , 1984, Brain Research.

[146]  Emery N. Brown,et al.  Toward an In Vivo Neuroimaging Template of Human Brainstem Nuclei of the Ascending Arousal, Autonomic, and Motor Systems , 2015, Brain Connect..

[147]  S. Silberstein,et al.  Vagus Nerve Stimulation and Headache , 2017, Headache.

[148]  Daniel Le Bars,et al.  The whole body receptive field of dorsal horn multireceptive neurones. , 2002, Brain research. Brain research reviews.

[149]  S. Dietrich,et al.  A novel transcutaneous vagus nerve stimulation leads to brainstem and cerebral activations measured by functional MRI / Funktionelle Magnetresonanztomographie zeigt Aktivierungen des Hirnstamms und weiterer zerebraler Strukturen unter transkutaner Vagusnervstimulation , 2008, Biomedizinische Technik. Biomedical engineering.

[150]  A. Duggan,et al.  Brain-stem areas tonically inhibiting dorsal horn neurones: Studies with microinjection of the GABA Analogue Piperidine-4-Sulphonic Acid , 1986, Pain.

[151]  Johannes Kornhuber,et al.  CNS BOLD fMRI Effects of Sham-Controlled Transcutaneous Electrical Nerve Stimulation in the Left Outer Auditory Canal – A Pilot Study , 2013, Brain Stimulation.

[152]  S. Kollias,et al.  Surface Anatomy of the Brain Stem and Cerebellum , 2009 .

[153]  A M Graybiel,et al.  The basal ganglia and adaptive motor control. , 1994, Science.

[154]  Karl J. Friston,et al.  Bayesian fMRI time series analysis with spatial priors , 2005, NeuroImage.

[155]  Sergio Cerutti,et al.  Brain Circuitry Supporting Multi-Organ Autonomic Outflow in Response to Nausea. , 2014, Cerebral cortex.

[156]  L. Stan Leung,et al.  Brain areas that influence general anesthesia , 2014, Progress in Neurobiology.

[157]  L. López‐Manzanares,et al.  [Vagus nerve stimulation in patients with migraine]. , 2013, Revista de neurologia.

[158]  V. Napadow,et al.  The Autonomic Brain: An Activation Likelihood Estimation Meta-Analysis for Central Processing of Autonomic Function , 2013, The Journal of Neuroscience.

[159]  Thomas C. Lee,et al.  Interventional MR Imaging for Deep-Brain Stimulation Electrode Placement. , 2016, Radiology.

[160]  G. Paxinos,et al.  Atlas of the Human Brain , 2000 .

[161]  Eduardo Colombari,et al.  The nucleus of the solitary tract and the coordination of respiratory and sympathetic activities , 2014, Front. Physiol..

[162]  Marta Bianciardi,et al.  Investigation of BOLD fMRI resonance frequency shifts and quantitative susceptibility changes at 7 T , 2014, Human brain mapping.

[163]  R. Lane,et al.  A model of neurovisceral integration in emotion regulation and dysregulation. , 2000, Journal of affective disorders.

[164]  Raymond J. Dolan,et al.  Parcellation of the human substantia nigra based on anatomical connectivity to the striatum , 2013, NeuroImage.

[165]  Pascal Carrive,et al.  The periaqueductal gray and defensive behavior: Functional representation and neuronal organization , 1993, Behavioural Brain Research.

[166]  Julian C. Matthews,et al.  Deep brain stimulation of the periaqueductal gray releases endogenous opioids in humans , 2017, NeuroImage.

[167]  J. Price,et al.  Prefrontal cortical projections to longitudinal columns in the midbrain periaqueductal gray in Macaque monkeys , 1998, The Journal of comparative neurology.

[168]  L. Becerra,et al.  Interictal Dysfunction of a Brainstem Descending Modulatory Center in Migraine Patients , 2008, PloS one.

[169]  B. Lau,et al.  The integrative role of the pedunculopontine nucleus in human gait. , 2015, Brain : a journal of neurology.

[170]  E. S. Watkins,et al.  Stereotaxic atlas of the human brainstem and cerebellar nuclei : a variability study , 1978 .

[171]  Manisha Aggarwal,et al.  B0‐orientation dependent magnetic susceptibility‐induced white matter contrast in the human brainstem at 11.7T , 2016, Magnetic resonance in medicine.

[172]  L. Meiners,et al.  Surgical Accuracy of 3-Tesla Versus 7-Tesla Magnetic Resonance Imaging in Deep Brain Stimulation for Parkinson Disease. , 2016, World Neurosurgery.

[173]  Emery N. Brown,et al.  In vivo functional connectome of human brainstem nuclei of the ascending arousal, autonomic, and motor systems by high spatial resolution 7-Tesla fMRI , 2016, Magnetic Resonance Materials in Physics, Biology and Medicine.

[174]  Stefan Maderwald,et al.  High-resolution anatomy of the human brain stem using 7-T MRI: improved detection of inner structures and nerves? , 2014, Neuroradiology.

[175]  M. Joyner,et al.  Regulation of blood pressure by the arterial baroreflex and autonomic nervous system. , 2013, Handbook of clinical neurology.

[176]  Julien Cohen-Adad,et al.  Identification of discrete functional subregions of the human periaqueductal gray , 2013, Proceedings of the National Academy of Sciences.

[177]  A. Pertovaara,et al.  Chapter 13 Descending inhibitory systems. , 2006, Handbook of clinical neurology.

[178]  C. Pollak Regulation of sleep rate and circadian consolidation of sleep and wakefulness in an infant. , 1994, Sleep.

[179]  G Becker,et al.  Vulnerability of the nigrostriatal system as detected by transcranial ultrasound , 1999, Neurology.

[180]  Trevor Sharp,et al.  5-HT and depression: is the glass half-full? , 2011, Current opinion in pharmacology.

[181]  J C Gore,et al.  A model for susceptibility artefacts from respiration in functional echo-planar magnetic resonance imaging. , 2000, Physics in medicine and biology.

[182]  C. Lowry,et al.  Functional topography of midbrain and pontine serotonergic systems: implications for synaptic regulation of serotonergic circuits , 2011, Psychopharmacology.

[183]  R. S. Hinks,et al.  Real‐time shimming to compensate for respiration‐induced B0 fluctuations , 2007, Magnetic resonance in medicine.

[184]  M. Munetz,et al.  Stimulation and arousal in self-mutilators. , 1979, The American journal of psychiatry.

[185]  H. Sapru,et al.  GABA and glycine receptors in the nucleus ambiguus mediate tachycardia elicited by chemical stimulation of the hypothalamic arcuate nucleus. , 2015, American journal of physiology. Heart and circulatory physiology.

[186]  C. Büchel,et al.  Activation of the Opioidergic Descending Pain Control System Underlies Placebo Analgesia , 2009, Neuron.

[187]  Jürgen R. Reichenbach,et al.  The future of susceptibility contrast for assessment of anatomy and function , 2012, NeuroImage.

[188]  T. Maehara,et al.  Origin, course and distribution of the nerves to the posterosuperior wall of the external acoustic meatus , 2014, Anatomical Science International.

[189]  F. Bloom,et al.  Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle , 1981, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[190]  W. Schultz Updating dopamine reward signals , 2013, Current Opinion in Neurobiology.

[191]  A. Harriott,et al.  Migraine is Associated With Altered Processing of Sensory Stimuli , 2014, Current Pain and Headache Reports.

[192]  Lawrence L. Wald,et al.  Laminar analysis of 7T BOLD using an imposed spatial activation pattern in human V1 , 2010, NeuroImage.

[193]  H. Fields,et al.  Evidence that disinhibition of brain stem neurones contributes to morphine analgesia , 1983, Nature.

[194]  K. M. Spyer,et al.  Neural organisation and control of the baroreceptor reflex. , 1981, Reviews of physiology, biochemistry and pharmacology.

[195]  John Huston,et al.  Direct visualization of Parkinson's disease by in vivo human brain imaging using 7.0T magnetic resonance imaging , 2011, Movement disorders : official journal of the Movement Disorder Society.

[196]  M. Kimura,et al.  NOTCH1 Expression Predicts Patient Prognosis in Esophageal Squamous Cell Cancer , 2013, European Surgical Research.

[197]  Kh. M. Saliba Regulation of blood pressure in thirst , 1984 .

[198]  A. Lang,et al.  Parkinson's disease. First of two parts. , 1998, The New England journal of medicine.

[199]  W. Gordy,et al.  Magnetic‐Susceptibility Anisotropy of CO and CS , 1970 .

[200]  Stephen D. Mayhew,et al.  Determination of the human brainstem respiratory control network and its cortical connections in vivo using functional and structural imaging , 2009, NeuroImage.

[201]  P. Goadsby,et al.  Diencephalic and brainstem mechanisms in migraine , 2011, Nature Reviews Neuroscience.

[202]  J. Coote Bulbospinal Serotonergic Pathways in the Control of Blood Pressure , 1990, Journal of cardiovascular pharmacology.

[203]  G. Gebhart,et al.  Characterization of inhibition of the spinal nociceptive tail-flick reflex in the rat from the medullary lateral reticular nucleus , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[204]  R Weissleder,et al.  Paramagnetic metal scavenging by melanin: MR imaging. , 1997, Radiology.

[205]  B Piallat,et al.  Effects of pedunculopontine nucleus area stimulation on gait disorders in Parkinson's disease. , 2010, Brain : a journal of neurology.

[206]  A I Basbaum,et al.  Endogenous pain control mechanisms: review and hypothesis , 1979 .

[207]  Bing Wu,et al.  Magnetic susceptibility anisotropy of human brain in vivo and its molecular underpinnings , 2012, NeuroImage.

[208]  V. Wedeen,et al.  Brain parenchyma motion: measurement with cine echo-planar MR imaging. , 1992, Radiology.

[209]  E. Brown,et al.  A point-process model of human heartbeat intervals: new definitions of heart rate and heart rate variability. , 2005, American journal of physiology. Heart and circulatory physiology.

[210]  Emery N. Brown,et al.  Brain correlates of autonomic modulation: Combining heart rate variability with fMRI , 2008, NeuroImage.

[211]  T. Aziz,et al.  Deep brain stimulation for phantom limb pain , 2005, Journal of Clinical Neuroscience.

[212]  S J Kish,et al.  Biochemical pathophysiology of Parkinson's disease. , 1987, Advances in neurology.

[213]  Sergio Cerutti,et al.  Neuroimaging brainstem circuitry supporting cardiovagal response to pain: a combined heart rate variability/ultrahigh-field (7 T) functional magnetic resonance imaging study , 2016, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[214]  A. Lang,et al.  Parkinson's disease. Second of two parts. , 1998, The New England journal of medicine.

[215]  P. Jezzard,et al.  Correction for geometric distortion in echo planar images from B0 field variations , 1995, Magnetic resonance in medicine.

[216]  Estimulación del nervio vago en pacientes migrañosos , 2013 .

[217]  Gary H. Duncan,et al.  Deep brain stimulation: a review of basic research and clinical studies , 1991, Pain.