Design and evaluation of a biomimetic agonist-antagonist active knee prosthesis

The loss of a limb is extremely debilitating. Unfortunately, today’s assistive technologies are still far from providing fully functional artificial limb replacements. Although lower extremity prostheses are currently better able to give assistance than their upper-extremity counterparts, important locomotion problems still remain for leg amputees. Instability, gait asymmetry, decreased walking speeds and high metabolic energy costs are some of the main challenges requiring the development of a new kind of prosthetic device. These challenges point to the need for highly versatile, fully integrated lower-extremity powered prostheses that can replicate the biological behavior of the intact human leg. This thesis presents the design and evaluation of a novel biomimetic active knee prosthesis capable of emulating intact knee biomechanics during level-ground walking. The knee design is motivated by a mono-articular prosthetic knee model comprised of a variable damper and two serieselastic clutch units spanning the knee joint. The powered knee system is comprised of two series-elastic actuators positioned in parallel in an agonist-antagonist configuration. This investigation hypothesizes that the biomimetic active-knee prosthesis, with a variable impedance control, can improve unilateral transfemoral amputee locomotion in level-ground walking, reducing the metabolic cost of walking at selfselected speeds. To evaluate this hypothesis, a preliminary study investigated the clinical impact of the active knee prosthesis on the metabolic cost of walking of four unilateral above-knee amputees. This preliminary study compared the antagonistic active knee prosthesis with subjects’ prescribed knee prostheses. The subjects’ prescribed prostheses encompass four of the leading prosthetic knee technologies commercially available, including passive and electronically controlled variable-damping prosthetic systems. Use of the novel biomimetic active knee prosthesis resulted in a metabolic cost reduction for all four subjects by an average of 5.8%. Kinematic and kinetic analyses indicate that the active knee can increase self-selected walking speed in addition to reducing upper body vertical displacement during walking by an average of 16%. The results of this investigation report for the first time a metabolic cost reduction when walking with a prosthetic system comprised of an electrically powered active knee and passive foot-ankle prostheses, as compared to walking with a conventional transfemoral prosthesis. With this work I aim to advance the field of biomechatronics, contributing to the development of integral assistive technologies that adapt to the needs of the physically challenged. Thesis Supervisor: Hugh Herr, Ph.D. Associate Professor of Media Arts and Sciences, and Health Sciences and Technology

[1]  D. Winter Biomechanical motor patterns in normal walking. , 1983, Journal of motor behavior.

[2]  Michael Goldfarb,et al.  Design and Control of a Powered Transfemoral Prosthesis , 2008, Int. J. Robotics Res..

[3]  J. Brockway Derivation of formulae used to calculate energy expenditure in man. , 1987, Human nutrition. Clinical nutrition.

[4]  J. Stepien,et al.  Activity levels among lower-limb amputees: self-report versus step activity monitor. , 2007, Archives of physical medicine and rehabilitation.

[5]  Woodie Claude Flowers A man-interactive simulator system for above-knee prosthetics studies. , 1973 .

[6]  J. Weber,et al.  Design of an agonist-antagonist active knee prosthesis , 2008, 2008 2nd IEEE RAS & EMBS International Conference on Biomedical Robotics and Biomechatronics.

[7]  N. H. Molen Energy/speed relation of below-knee amputees walking on a motor-driven treadmill , 1973, Internationale Zeitschrift für angewandte Physiologie einschließlich Arbeitsphysiologie.

[8]  Hugh Herr,et al.  User-adaptive control of a magnetorheological prosthetic knee , 2003, Ind. Robot.

[9]  Akin O. Kapti,et al.  Design and control of an active artificial knee joint , 2006 .

[10]  Hugh Herr,et al.  Agonist-antagonist active knee prosthesis: a preliminary study in level-ground walking. , 2009, Journal of rehabilitation research and development.

[11]  R. Riener,et al.  Stair ascent and descent at different inclinations. , 2002, Gait & posture.

[12]  Tad McGeer,et al.  Passive Dynamic Walking , 1990, Int. J. Robotics Res..

[13]  Michael Goldfarb,et al.  Self-contained powered knee and ankle prosthesis: Initial evaluation on a transfemoral amputee , 2009, 2009 IEEE International Conference on Rehabilitation Robotics.

[14]  Hugh M. Herr,et al.  Powered ankle-foot prosthesis , 2008, IEEE Robotics & Automation Magazine.

[15]  Hugh M. Herr,et al.  Biomimetic Prosthetic Knee Using Antagonistic Muscle-Like Activation , 2008 .

[16]  S.K. Au,et al.  Powered Ankle-Foot Prosthesis for the Improvement of Amputee Ambulation , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[17]  R. Waters,et al.  The energy expenditure of normal and pathologic gait. , 1999, Gait & posture.

[18]  Samuel Kwok Wai Au,et al.  Powered ankle-foot prosthesis for the improvement of amputee walking economy , 2007 .

[19]  Susan Sienko Thomas,et al.  Comparison of the Seattle Lite Foot and Genesis II Prosthetic Foot during walking and running , 2000 .

[20]  Alfred D. Grant Gait Analysis: Normal and Pathological Function , 2010 .

[21]  Ari Wilkenfeld,et al.  Biologically inspired autoadaptive control of a knee prosthesis , 2000 .

[22]  Michael Lars Palmer,et al.  Sagittal plane characterization of normal human ankle function across a range of walking gait speeds , 2002 .

[23]  Grant Elliott,et al.  Design and evaluation of a quasi-passive robotic knee brace: on the effects of parallel elasticity on human running , 2012 .

[24]  J Perry,et al.  Below-knee amputee gait with dynamic elastic response prosthetic feet: a pilot study. , 1990, Journal of rehabilitation research and development.

[25]  H. Hermens,et al.  Energy storage and release of prosthetic feet Part 1: Biomechanical analysis related to user benefits , 1997, Prosthetics and orthotics international.

[26]  Matthew M. Williamson,et al.  Series elastic actuators , 1995, Proceedings 1995 IEEE/RSJ International Conference on Intelligent Robots and Systems. Human Robot Interaction and Cooperative Robots.

[27]  Ken Endo,et al.  A quasi-passive model of human leg function in level-ground walking , 2006, 2006 IEEE/RSJ International Conference on Intelligent Robots and Systems.

[28]  Hugh Herr,et al.  Antagonistic active knee prosthesis. A metabolic cost of walking comparison with a variable-damping prosthetic knee , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[29]  C W Radcliffe The Knud Jansen Lecture: above-knee prosthetics. , 1977, Prosthetics and orthotics international.

[30]  Hugh M. Herr,et al.  Powered Ankle--Foot Prosthesis Improves Walking Metabolic Economy , 2009, IEEE Transactions on Robotics.

[31]  S. Collins,et al.  Recycling Energy to Restore Impaired Ankle Function during Human Walking , 2010, PloS one.

[32]  Luke M. Mooney Variable damping controller for a prosthetic knee during swing extension , 2012 .

[33]  J. Lehmann,et al.  Comprehensive analysis of dynamic elastic response feet: Seattle Ankle/Lite Foot versus SACH foot. , 1993, Archives of physical medicine and rehabilitation.

[34]  H. Herr,et al.  Adaptive control of a variable-impedance ankle-foot orthosis to assist drop-foot gait , 2004, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[35]  J. Dowling,et al.  Body Segment Parameter Estimation of the Human Lower Leg Using an Elliptical Model with Validation from DEXA , 2006, Annals of Biomedical Engineering.