Consensus statement on the terminology and classification of central neck dissection for thyroid cancer.

BACKGROUND The primary goals of this interdisciplinary consensus statement are to review the relevant anatomy of the central neck compartment, to identify the nodal subgroups within the central compartment commonly involved in thyroid cancer, and to define a consistent terminology relevant to the central compartment neck dissection. SUMMARY The most commonly involved central lymph nodes in thyroid carcinoma are the prelaryngeal (Delphian), pretracheal, and the right and left paratracheal nodal basins. A central neck dissection includes comprehensive, compartment-oriented removal of the prelaryngeal and pretracheal nodes and at least one paratracheal lymph node basin. A designation should be made as to whether a unilateral or bilateral dissection is performed and on which side (left or right) in unilateral cases. Lymph node "plucking" or "berry picking" implies removal only of the clinically involved nodes rather than a complete nodal group within the compartment and is not recommended. A therapeutic central compartment neck dissection implies that nodal metastasis is apparent clinically (preoperatively or intraoperatively) or by imaging (clinically N1a). A prophylactic/elective central compartment dissection implies nodal metastasis is not detected clinically or by imaging (clinically N0). CONCLUSION Central neck dissection at a minimum should consist of removal of the prelaryngeal, pretracheal, and paratracheal lymph nodes. The description of a central neck dissection should include both the indication (therapeutic vs. prophylactic/elective) and the extent of the dissection (unilateral or bilateral).

[1]  S. Paik,et al.  Clinical Efficacy of Sentinel Lymph Node Biopsy Using Methylene Blue Dye in Clinically Node-Negative Papillary Thyroid Carcinoma , 2012, Annals of Surgical Oncology.

[2]  Y. Ko,et al.  Expression of Sodium–Iodide Symporter and TSH Receptor in Subclinical Metastatic Lymph Nodes of Papillary Thyroid Microcarcinoma , 2012, Annals of Surgical Oncology.

[3]  P. Friedlander,et al.  Impact of Extensive Neck Dissection on Survival from Papillary Thyroid Cancer , 2011, ORL.

[4]  J. Pasieka,et al.  Well-Differentiated Thyroid Carcinomas: Management of the Central Lymph Node Compartment and Emerging Biochemical Markers , 2011, Journal of oncology.

[5]  B. Lang,et al.  The Role of Prophylactic Central Neck Dissection in Differentiated Thyroid Carcinoma: Issues and Controversies , 2011, Journal of oncology.

[6]  S. Leboulleux,et al.  Guide de bonnes pratiques pour l’usage de l’échographie cervicale et des techniques écho-guidées dans la prise en charge des cancers thyroïdiens différenciés de souche vésiculaire , 2011 .

[7]  G. Cote,et al.  Management of medullary thyroid carcinoma and MEN2 syndromes in childhood , 2011, Nature Reviews Endocrinology.

[8]  M. Schlumberger,et al.  Good practice guide for cervical ultrasound scan and echo-guided techniques in treating differentiated thyroid cancer of vesicular origin. , 2011, Annales d'endocrinologie.

[9]  L. Yip,et al.  Thyroid carcinoma: the surgeon's perspective. , 2011, Radiologic clinics of North America.

[10]  J. Shah,et al.  Incidence and Significance of Delphian Node Metastasis in Papillary Thyroid Cancer , 2011, Annals of surgery.

[11]  D. Hartl,et al.  Central Compartment Neck Dissection for Thyroid Cancer: A Surgical Technique , 2011, World Journal of Surgery.

[12]  A. Shaha,et al.  Central compartment dissection for well differentiated thyroid cancer … and the band plays on , 2011, Current opinion in otolaryngology & head and neck surgery.

[13]  J. Roh,et al.  Central Lymph Node Metastasis of Unilateral Papillary Thyroid Carcinoma: Patterns and Factors Predictive of Nodal Metastasis, Morbidity, and Recurrence , 2011, Annals of Surgical Oncology.

[14]  S. Roman,et al.  Differentiated thyroid cancer: an update , 2011, Current opinion in oncology.

[15]  G. Doherty,et al.  An examination of recently revised differentiated thyroid cancer guidelines , 2011, Current opinion in oncology.

[16]  Serkan Sarı,et al.  Radio-guided excision of parathyroid lesions in patients who had previous neck surgeries: a safe and easy technique for re-operative parathyroid surgery. , 2011, International journal of surgery.

[17]  G. Randolph Papillary cancer nodal surgery and the advisability of prophylactic central neck dissection: primum, non nocere. , 2010, Surgery.

[18]  W. Burns,et al.  Differentiated thyroid cancer. , 2010, Seminars in oncology.

[19]  P. Bradley,et al.  Delphian node metastasis in head and neck cancers—Oracle or myth? , 2010, Journal of surgical oncology.

[20]  E. Pearce,et al.  Surgery of well-differentiated thyroid carcinoma: the pendulum swings back in the central neck. , 2010, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[21]  M. Urken Management of well-differentiated thyroid cancer in 2010: perspectives of a head and neck surgical oncologist. , 2010, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[22]  J. Roh,et al.  Role of sentinel lymph node biopsy in thyroid cancer , 2010, Expert review of anticancer therapy.

[23]  Q. Duh,et al.  Central neck lymph node dissection for papillary thyroid cancer: the reliability of surgeon judgment in predicting which patients will benefit. , 2010, Surgery.

[24]  H. Dralle,et al.  Tumortyp- und tumorstadienorientiertes chirurgisches Konzept bei Karzinomen der Schilddrüse , 2010, Der Onkologe.

[25]  E. Kandil,et al.  Considerations for personalized surgery in patients with papillary thyroid cancer. , 2010, Thyroid : official journal of the American Thyroid Association.

[26]  A. Giuliano,et al.  Sentinel Lymph Node Biopsy for Papillary Thyroid Cancer: 12 Years of Experience at a Single Institution , 2010, Annals of Surgical Oncology.

[27]  S. Carty,et al.  Thyroid surgery and surgeons: the common interest. , 2010, Thyroid : official journal of the American Thyroid Association.

[28]  G. Doherty,et al.  Surgical management of cervical lymph nodes in differentiated thyroid cancer. , 2010, Otolaryngologic clinics of North America.

[29]  S. Pai,et al.  Reoperation for recurrent/persistent well-differentiated thyroid cancer. , 2010, Otolaryngologic clinics of North America.

[30]  Douglas B. Evans,et al.  Do Practice Patterns Reflect Practice Guidelines? , 2010, Annals of Surgical Oncology.

[31]  S. Roman,et al.  Medullary Thyroid Cancer: Are Practice Patterns in the United States Discordant From American Thyroid Association Guidelines? , 2010, Annals of Surgical Oncology.

[32]  Stephanie L. Lee,et al.  Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. , 2009, Thyroid : official journal of the American Thyroid Association.

[33]  J. Califano,et al.  Consensus statement on the classification and terminology of neck dissection. , 2008, Archives of otolaryngology--head & neck surgery.

[34]  P. Levine,et al.  Neck dissection classification update: revisions proposed by the American Head and Neck Society and the American Academy of Otolaryngology-Head and Neck Surgery. , 2002, Archives of otolaryngology--head & neck surgery.

[35]  J E Medina,et al.  Standardizing neck dissection terminology. Official report of the Academy's Committee for Head and Neck Surgery and Oncology. , 1991, Archives of otolaryngology--head & neck surgery.