TiO2–silica mediated one pot three component 1,3-dipolar cycloaddition reaction: a facile and rapid synthesis of dispiro acenaphthenone/oxindole [indanedione/oxindole] pyrroloisoquinoline ring systems

[1]  R. Raghunathan,et al.  A novel entry into 1-methyl- and 1-aryl-octahydropyrrolo[3,4-b]pyrroles and their N-1–C-2 fused derivatives: stereoselective synthesis via an intramolecular azomethine ylide cycloaddition reaction , 2005 .

[2]  R. Raghunathan,et al.  A novel access to highly functionalised β-lactams by regio- and stereoselective 1,3-dipolar cycloaddition reaction , 2005 .

[3]  R. Raghunathan,et al.  A regioselective synthesis of dispiro[oxindole-cyclohexanone]pyrrolidines and dispiro[oxindole-hexahydroindazole]pyrrolidines by sequential 1,3-dipolar cycloaddition and annulation through a microwave induced solvent-free approach , 2005 .

[4]  R. Raghunathan,et al.  A facile synthesis of novel dispiroheterocycles through solvent-free microwave-assisted [3+2] cycloaddition of azomethine ylides , 2004 .

[5]  A. A. Raj,et al.  Synthesis, antimicrobial and antifungal activity of a new class of spiro pyrrolidines. , 2003, Bioorganic & medicinal chemistry.

[6]  A. A. Raj,et al.  A Novel Entry into a New Class of Spiroheterocyclic Framework: Regioselective Synthesis of Dispiro[oxindole-cyclohexanone]pyrrolidines and Dispiro[oxindolehexahydroindazole]pyrrolidines. , 2001 .

[7]  R. Raghunathan,et al.  Synthesis of highly substituted spiropyrrolidines via 1,3-dipolar cycloaddition reaction of N-metalated azomethine ylides , 2001 .

[8]  R. Raghunathan,et al.  High, Exoselective Diels–Alder Reaction in 5.0M Lithium Perchlorate in Diethyl Ether Medium: Efficient Synthesis of Novel Heterocyclic Derivatives Containing a Spirobicyclo[2.2.1]heptane System , 2000 .

[9]  M. Nyerges.  2-Oxoindolin-3-ylidene derivatives as 2π components in 1,3-dipolar cycloadditions of azomethine ylides , 2001 .

[10]  Walajapet G. Rajeswaran,et al.  Synthesis of 5-[(Indol-2-on-3-yl)methyl]-2,2-dimethyl-1,3- dioxane-4,6-diones and Spirocyclopropyloxindole Derivatives. Potential Aldose Reductase Inhibitors† , 1999 .

[11]  A. Petit,et al.  New Solvent-Free Organic Synthesis Using Focused Microwaves , 1998 .

[12]  W. Ryan,et al.  Solution phase synthesis of a spiro[pyrrolidine-2,3′-oxindole] library via a three component 1,3-dipolar cycloaddition reaction , 1998 .

[13]  S. Caddick.  Microwave assisted organic reactions , 1995 .

[14]  H. Waldmann.  AMINO-ACID ESTERS - VERSATILE CHIRAL AUXILIARY GROUPS FOR THE ASYMMETRIC-SYNTHESIS OF NITROGEN-HETEROCYCLES , 1995 .

[15]  P. Grieco,et al.  Biomimetic total synthesis of pseudotabersonine : a novel oxindole-based approach to construction of Aspidosperma alkaloids , 1993 .

[16]  S. Pelletier.  Alkaloids: Chemical and Biological Perspectives , 1992, Alkaloids: Chemical and Biological Perspectives.

[17]  R. Howe,et al.  Spiroheterocycles from the reaction of nitrile oxides with 3-methylenephthalimidines , 1990 .

[18]  R. Grigg,et al.  X=Y-ZH compounds as potential 1,3-Dipoles. Part 281,2 the iminium ion route to azomethine ylides. background and reaction of amines with bifunctional ketones. , 1990 .

[19]  J. Skiles,et al.  Spiro indolinone beta-lactams, inhibitors of poliovirus and rhinovlrus 3C-proteinases , 1990 .

[20]  R. Grigg,et al.  X=Y-ZH compounds as potential 13-dipoles. Part 29. The iminium ion route to azomethine ylides. Reaction of cyclic secondary amines with mono- and bI- functional aldehydes☆☆☆ , 1990 .

[21]  M. Amici,et al.  Nitrile oxides in medicinal chemistry-2. synthesis of the two enantiomers of dihydromuscimol , 1990 .

[22]  R. Grigg,et al.  XY–ZH systems as potential 1,3-dipoles. Part 12. Mechanism of formation of azomethine ylides via the decarboxylative route from α-amino acids , 1988 .

[23]  R. Grigg,et al.  XY–ZH systems as potential 1,3-dipoles. Part 11. Stereochemistry of 1,3-dipoles generated by the decarboxylative route to azomethine ylides , 1988 .

[24]  L. Overman,et al.  Synthesis studies directed toward gelsemine. Preparation of an advanced pentacyclic intermediate , 1988 .

[25]  A. Kozikowski.  The isoxazoline route to the molecules of nature , 1984 .

[26]  A. Padwa.  1,3-Dipolar Cycloaddition Chemistry , 1984 .

[27]  T. Ōishi,et al.  The synthesis of 3-spirooxindole derivatives. VIII. Total syntheses of (.+-.)-formosanine, (.+-.)-isoformosanine, (.+-.)-mitraphylline and (.+-.)-isomitraphylline. , 1976 .

[28]  T. Ōishi,et al.  The Synthesis of 3-Spirooxindole Derivatives. VII. Total Synthesis of Alkaloids (±)-Rhynchophylline and (±)-Isorhynchophylline , 1975 .

[29]  Kunio Suzuki,et al.  Formic Acid Reduction. XX. Reduction of 2-Benzylidene-1, 3-indandiones , 1974 .

[30]  T. Ōishi,et al.  The synthesis of 3-spirooxindole derivatives. Total syntheses of dl-formosanine, dl-isoformosanine, dl-mitraphylline and dl-isomitraphylline , 1974 .

[31]  E. E. Tamelen,et al.  Total synthesis of rhyncophyllol and dl-isorhyncophyllol , 1969 .

[32]  J. E. Francis,et al.  The configuration of annotinine and some rearrangements , 1961 .

[33]  H. G. Lindwall,et al.  A CONDENSATION OF ACETOPHENONE WITH ISATIN BY THE KNOEVENAGEL METHOD1 , 1932 .