Wavelet packet energy, Tsallis entropy and statistical parameterization for support vector-based and neural-based classification of mammographic regions

This work develops a support vector and neural-based classification of mammographic regions by applying statistical, wavelet packet energy and Tsallis entropy parameterization. From the first four wavelet packet decomposition levels, four different feature sets were evaluated using two-sample Kolmogorov-Smirnov test (KS-test) and, in one case, principal component analysis (PCA). Feature selection was performed applying a hybrid scheme integrating non-parametric KS-test, correlation analysis, a logistic regression (LR) model and sequential forward selection (SFS). The top selected features (depending on the selected wavelet decomposition level) produced the best classification performances in comparison to other well-known feature selection methods. The classification of the data was carried out using several support vector machine (SVM) schemes and multi-layer perceptron (MLP) neural networks. The new set of features improved significantly the classification performance of mammographic regions using conventional SVMs and MLPs.

[1]  Brijesh Verma,et al.  Novel network architecture and learning algorithm for the classification of mass abnormalities in digitized mammograms , 2008, Artif. Intell. Medicine.

[2]  Dan Roth,et al.  Generalization Bounds for the Area Under the ROC Curve , 2005, J. Mach. Learn. Res..

[3]  Nicandro Cruz-Ramírez,et al.  Diagnosis of breast cancer using Bayesian networks: A case study , 2007, Comput. Biol. Medicine.

[4]  John A. Swets,et al.  Evaluation of diagnostic systems : methods from signal detection theory , 1982 .

[5]  Harris Georgiou,et al.  Significance analysis of qualitative mammographic features, using linear classifiers, neural networks and support vector machines. , 2005, European journal of radiology.

[6]  Nikos Dimitropoulos,et al.  Multi-scaled morphological features for the characterization of mammographic masses using statistical classification schemes , 2007, Artif. Intell. Medicine.

[7]  Brijesh Verma,et al.  A novel soft cluster neural network for the classification of suspicious areas in digital mammograms , 2009, Pattern Recognit..

[8]  Simon Haykin,et al.  Neural Networks: A Comprehensive Foundation , 1998 .

[9]  Ronald R. Coifman,et al.  Signal processing and compression with wavelet packets , 1994 .

[10]  Ling Guan,et al.  A CAD System for the Automatic Detection of Clustered Microcalcification in Digitized Mammogram Films , 2000, IEEE Trans. Medical Imaging.

[11]  K. Kinkel,et al.  Computer-aided detection (CAD) in mammography: does it help the junior or the senior radiologist? , 2005, European journal of radiology.

[12]  Sergios Theodoridis,et al.  Pattern Recognition, Fourth Edition , 2008 .

[13]  Andrew W. Moore,et al.  Logistic regression for data mining and high-dimensional classification , 2004 .

[14]  Dimitrios I. Fotiadis,et al.  Improvement of microcalcification cluster detection in mammography utilizing image enhancement techniques , 2008, Comput. Biol. Medicine.

[15]  Stéphane Mallat,et al.  A Theory for Multiresolution Signal Decomposition: The Wavelet Representation , 1989, IEEE Trans. Pattern Anal. Mach. Intell..

[16]  Du-Yih Tsai,et al.  Computerized classification of microcalcifications on mammograms using fuzzy logic and genetic algorithm , 2004, SPIE Medical Imaging.

[17]  Defeng Wang,et al.  Automatic detection of breast cancers in mammograms using structured support vector machines , 2009, Neurocomputing.

[18]  Rangaraj M. Rangayyan,et al.  DETECTION AND CLASSIFICATION OF MAMMOGRAPHIC CALCIFICATIONS , 1993 .

[19]  A. C. Rencher Methods of multivariate analysis , 1995 .

[20]  Amparo Vilarrasa Andrés Sistema inteligente para la detección y diagnóstico de patología mamaria , 2012 .

[21]  Claudio Marrocco,et al.  A computer-aided detection system for clustered microcalcifications , 2010, Artif. Intell. Medicine.

[22]  Juan F. Ramirez-Villegas,et al.  Microcalcification Detection in Mammograms Using Difference of Gaussians Filters and a Hybrid Feedforward-Kohonen Neural Network , 2009, 2009 XXII Brazilian Symposium on Computer Graphics and Image Processing.

[23]  G Coppini,et al.  Detection of single and clustered microcalcifications in mammograms using fractals models and neural networks. , 2004, Medical engineering & physics.

[24]  Kunio Doi,et al.  Computer-aided diagnosis in medical imaging: Historical review, current status and future potential , 2007, Comput. Medical Imaging Graph..

[25]  Heng-Da Cheng,et al.  Approaches for automated detection and classification of masses in mammograms , 2006, Pattern Recognit..

[26]  Nikolas P. Galatsanos,et al.  A support vector machine approach for detection of microcalcifications , 2002, IEEE Transactions on Medical Imaging.

[27]  Nikhil R. Pal,et al.  A multi-stage neural network aided system for detection of microcalcifications in digitized mammograms , 2008, Neurocomputing.

[28]  Robert M. Nishikawa,et al.  Microcalcification Classification Assisted by Content-Based Image Retrieval for Breast Cancer Diagnosis , 2007, 2007 IEEE International Conference on Image Processing.

[29]  Márcio Portes de Albuquerque,et al.  Image thresholding using Tsallis entropy , 2004, Pattern Recognit. Lett..

[30]  M. Victor Wickerhauser,et al.  Adapted wavelet analysis from theory to software , 1994 .

[31]  Ian W. Ricketts,et al.  The Mammographic Image Analysis Society digital mammogram database , 1994 .

[32]  N C Ramirez,et al.  DIAGNOSIS OF BREAST CANCER USING BAYESIAN NETWORKS: A CASE STUDY , 2007 .

[33]  Tom Fawcett,et al.  An introduction to ROC analysis , 2006, Pattern Recognit. Lett..

[34]  G. Kokkinakis,et al.  Computer aided diagnosis of breast cancer in digitized mammograms. , 2002, Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society.

[35]  Rangaraj M. Rangayyan,et al.  A review of computer-aided diagnosis of breast cancer: Toward the detection of subtle signs , 2007, J. Frankl. Inst..

[36]  Ronald R. Coifman,et al.  Entropy-based algorithms for best basis selection , 1992, IEEE Trans. Inf. Theory.

[37]  Nan-Chyuan Tsai,et al.  Computer-aided diagnosis for early-stage breast cancer by using Wavelet Transform , 2011, Comput. Medical Imaging Graph..

[38]  Gwo Giun Lee,et al.  On Digital Mammogram Segmentation and Microcalcification Detection Using Multiresolution Wavelet Analysis , 1997, CVGIP Graph. Model. Image Process..