Practical Application of Toxicogenomics for Profiling Toxicant-Induced Biological Perturbations
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Naoki Kiyosawa | Sunao Manabe | N. Kiyosawa | S. Manabe | A. Sanbuissho | T. Yamoto | Atsushi Sanbuissho | Takashi Yamoto
[1] Adriano V. Werhli,et al. Reverse Engineering Gene Regulatory Networks with Various Machine Learning Methods , 2008 .
[2] Avi Ma’ayan. Insights into the Organization of Biochemical Regulatory Networks Using Graph Theory Analyses* , 2009, Journal of Biological Chemistry.
[3] Mark Craven,et al. EDGE: A Centralized Resource for the Comparison, Analysis, and Distribution of Toxicogenomic Information , 2005, Molecular Pharmacology.
[4] N. Kiyosawa,et al. Evaluation of glutathione deficiency in rat livers by microarray analysis. , 2004, Biochemical pharmacology.
[5] M Kanehisa,et al. Organizing and computing metabolic pathway data in terms of binary relations. , 1997, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing.
[6] Steven C. Lawlor,et al. GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways , 2002, Nature Genetics.
[7] M. Negishi,et al. Phenobarbital Confers its Diverse Effects by Activating the Orphan Nuclear Receptor Car , 2006, Drug metabolism reviews.
[8] Mellar P. Davis,et al. The pharmacological importance of cytochrome CYP3A4 in the palliation of symptoms: review and recommendations for avoiding adverse drug interactions , 2007, Supportive Care in Cancer.
[9] N. Kiyosawa,et al. Scoring multiple toxicological endpoints using a toxicogenomic database. , 2009, Toxicology letters.
[10] Ivan Rusyn,et al. Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.
[11] N. Kiyosawa,et al. A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats. , 2008, Toxicology.
[12] Roland Eils,et al. Group testing for pathway analysis improves comparability of different microarray datasets , 2006, Bioinform..
[13] J. Waring,et al. Interlaboratory evaluation of rat hepatic gene expression changes induced by methapyrilene. , 2004, Environmental health perspectives.
[14] Matthew A. Hibbs,et al. Visualization of omics data for systems biology , 2010, Nature Methods.
[15] N. Kiyosawa,et al. Gene set-level network analysis using a toxicogenomics database. , 2010, Genomics.
[16] Neil Kaplowitz,et al. Idiosyncratic drug hepatotoxicity , 2005, Nature Reviews Drug Discovery.
[17] Atsushi Ono,et al. Identification of glutathione depletion-responsive genes using phorone-treated rat liver. , 2007, The Journal of toxicological sciences.
[18] Atsushi Ono,et al. Gene expression profiling in rat liver treated with compounds inducing phospholipidosis. , 2008, Toxicology and applied pharmacology.
[19] Darrell R Boverhof,et al. Toxicogenomics in risk assessment: applications and needs. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[20] M. Ashburner,et al. Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.
[21] H. Kitano. Towards a theory of biological robustness , 2007, Molecular systems biology.
[22] Kenji Takami,et al. A toxicogenomic approach to drug-induced phospholipidosis: analysis of its induction mechanism and establishment of a novel in vitro screening system. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.
[23] Shibing Deng,et al. Cross-site comparison of gene expression data reveals high similarity. , 2004, Environmental health perspectives.
[24] R G Ulrich,et al. Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles. , 2001, Toxicology and applied pharmacology.
[25] R G Ulrich,et al. Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity. , 2001, Toxicology letters.
[26] J. Waring,et al. Clofibrate-induced gene expression changes in rat liver: a cross-laboratory analysis using membrane cDNA arrays. , 2004, Environmental health perspectives.
[27] N. Kiyosawa,et al. Utilization of a one-dimensional score for surveying chemical-induced changes in expression levels of multiple biomarker gene sets using a large-scale toxicogenomics database. , 2006, The Journal of toxicological sciences.
[28] Alex E. Lash,et al. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository , 2002, Nucleic Acids Res..
[29] Jean YH Yang,et al. Bioconductor: open software development for computational biology and bioinformatics , 2004, Genome Biology.
[30] N. Kiyosawa,et al. Toxicogenomic Biomarkers for Liver Toxicity , 2009, Journal of toxicologic pathology.
[31] T. Urushidani. Prediction of Hepatotoxicity Based on the Toxicogenomics Database , 2008 .
[32] P. Shannon,et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.
[33] Michael C. Rosenstein,et al. The comparative toxicogenomics database: a cross-species resource for building chemical-gene interaction networks. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[34] Hans Lehrach,et al. A comparison of oligonucleotide and cDNA-based microarray systems. , 2004, Physiological genomics.
[35] J. Schellens,et al. Concise review: Clinical relevance of drug drug and herb drug interactions mediated by the ABC transporter ABCB1 (MDR1, P-glycoprotein). , 2007, The oncologist.
[36] R. Ulrich,et al. Overview of an interlaboratory collaboration on evaluating the effects of model hepatotoxicants on hepatic gene expression. , 2004, Environmental health perspectives.
[37] Yumiko Sakai,et al. Applications of microarrays with toxicologically relevant genes (tox genes) for the evaluation of chemical toxicants in Sprague Dawley rats in vivo and human hepatocytes in vitro. , 2004, Mutation research.
[38] T. Monks,et al. The contribution of bromobenzene to our current understanding of chemically-induced toxicities. , 1988, Life sciences.
[39] M. Fielden,et al. Interlaboratory evaluation of genomic signatures for predicting carcinogenicity in the rat. , 2008, Toxicological sciences : an official journal of the Society of Toxicology.
[40] Pierre R. Bushel,et al. CEBS—Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data , 2007, Nucleic Acids Res..
[41] M. Severgnini,et al. Strategies for comparing gene expression profiles from different microarray platforms: application to a case-control experiment. , 2006, Analytical Biochemistry.
[42] Sergio Contrino,et al. ArrayExpress—a public repository for microarray gene expression data at the EBI , 2004, Nucleic Acids Res..
[43] H. Ellinger-Ziegelbauer,et al. Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies. , 2008, Mutation research.