Potential of Plant Essential Oils and Their Components in Animal Agriculture – in vitro Studies on Antibacterial Mode of Action

The antimicrobial activity of essential oils and their components has been recognized for several years. Essential oils are produced as secondary metabolites by many plants and can be distilled from all different portions of plants. The recent emergence of bacteria resistant to multiple antibiotics has spurred research into the use of essential oils as alternatives. Recent research has demonstrated that many of these essential oils have beneficial effects for livestock, including reduction of foodborne pathogens in these animals. Numerous studies have been made into the mode of action of essential oils, and the resulting elucidation of bacterial cell targets has contributed to new perspectives on countering antimicrobial resistance and pathogenicity of these bacteria. In this review, an overview of the current knowledge about the antibacterial mode of action of essential oils and their constituents is provided.

[1]  S. Ricke,et al.  Salmonella Control in Food Production: Current Issues and Perspectives in the United States , 2015 .

[2]  C. Hofacre,et al.  Effect of essential oil compound on shedding and colonization of Salmonella enterica serovar Heidelberg in broilers. , 2013, Poultry science.

[3]  H. Nikaido Molecular Basis of Bacterial Outer Membrane Permeability Revisited , 2003, Microbiology and Molecular Biology Reviews.

[4]  B. Poolman,et al.  Interactions of cyclic hydrocarbons with biological membranes. , 1994, The Journal of biological chemistry.

[5]  C. Phillips,et al.  The mechanism of action of a citrus oil blend against Enterococcus faecium and Enterococcus faecalis , 2009, Journal of applied microbiology.

[6]  R. Holley,et al.  Mechanisms of Bactericidal Action of Cinnamaldehyde against Listeria monocytogenes and of Eugenol against L. monocytogenes and Lactobacillus sakei , 2004, Applied and Environmental Microbiology.

[7]  R. Coppola,et al.  Effect of Essential Oils on Pathogenic Bacteria , 2013, Pharmaceuticals.

[8]  G. Nychas,et al.  A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol , 2001, Journal of applied microbiology.

[9]  S. Kjelleberg,et al.  Is there a role for quorum sensing signals in bacterial biofilms? , 2002, Current opinion in microbiology.

[10]  J. Scheffer,et al.  Antimicrobial activities of essential oils , 1987, Pharmaceutisch Weekblad.

[11]  S. Ibrahim,et al.  Antimicrobial herb and spice compounds in food. , 2010 .

[12]  A D Russell,et al.  Activity and mechanisms of action of selected biocidal agents on Gram-positive and -negative bacteria. , 2003, Journal of applied microbiology.

[13]  D. Veal,et al.  Fluorescence staining and flow cytometry for monitoring microbial cells. , 2000, Journal of immunological methods.

[14]  J. Warmington,et al.  Determining the Antimicrobial Actions of Tea Tree Oil , 2001, Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry.

[15]  K. Baek,et al.  Antibacterial mode of action of Ginkgo biloba leaf essential oil: Effect on morphology and membrane permeability , 2015 .

[16]  T. Katsu,et al.  Bacterial cytoplasmic membrane permeability assay using ion-selective electrodes. , 2004, Journal of microbiological methods.

[17]  J. Liu,et al.  In vitro rumen fermentation and methane production are influenced by active components of essential oils combined with fumarate. , 2013, Journal of animal physiology and animal nutrition.

[18]  H. Nikaido,et al.  Outer membranes of Gram‐negative bacteria are permeable to steroid probes , 1992, Molecular microbiology.

[19]  H. Alakomi,et al.  Characterization of the action of selected essential oil components on gram-negative bacteria , 1998 .

[20]  S. Deans,et al.  Antibacterial properties of plant essential oils , 1987 .

[21]  E. Smid,et al.  Mechanisms of Action of Carvacrol on the Food-Borne Pathogen Bacillus cereus , 1999, Applied and Environmental Microbiology.

[22]  J. Shimada,et al.  The antibacterial effects of terpene alcohols on and their mode of action , 2004 .

[23]  Francisco A. Ocaña,et al.  Yield and composition of the essential oil of Thymus serpylloides subsp. serpylloides , 1994 .

[24]  U. Chaudhary,et al.  Quorum sensing and Bacterial Pathogenicity: From Molecules to Disease , 2011, Journal of laboratory physicians.

[25]  J. Shimada,et al.  The antibacterial effects of terpene alcohols on Staphylococcus aureus and their mode of action. , 2004, FEMS microbiology letters.

[26]  F. Sánchez-Vizcaíno,et al.  The impact of a specific blend of essential oil components and sodium butyrate in feed on growth performance and Salmonella counts in experimentally challenged broilers. , 2014, Poultry science.

[27]  M. Lacroix,et al.  Inhibitory effects of selected plant essential oils on the growth of four pathogenic bacteria: E. coli O157:H7, Salmonella Typhimurium, Staphylococcus aureus and Listeria monocytogenes , 2007 .

[28]  M. Lacroix,et al.  Antimicrobial activity of mustard essential oil against Escherichia coli O157:H7 and Salmonella typhi , 2009 .

[29]  S. Ricke,et al.  Citrus products decrease growth of E. coli O157:H7 and Salmonella typhimurium in pure culture and in fermentation with mixed ruminal microorganisms in vitro. , 2008, Foodborne pathogens and disease.

[30]  R. Figueiredo,et al.  Cytotoxic Effects of Origanum vulgare L. and Rosmarinus officinalis L. Essential Oils Alone and Combined at Sublethal Amounts on Pseudomonas fluorescens in a Vegetable Broth , 2013 .

[31]  J. Abrini,et al.  Functional and ultrastructural changes in Pseudomonas aeruginosa and Staphylococcus aureus cells induced by Cinnamomum verum essential oil , 2010, Journal of applied microbiology.

[32]  G. Fraenkel The raison d'ĕtre of secondary plant substances; these odd chemicals arose as a means of protecting plants from insects and now guide insects to food. , 1959, Science.

[33]  Francesco Castelli,et al.  Mechanisms of Antibacterial Action of Three Monoterpenes , 2005, Antimicrobial Agents and Chemotherapy.

[34]  H. J. Dorman,et al.  Antimicrobial agents from plants: antibacterial activity of plant volatile oils , 2000, Journal of applied microbiology.

[35]  S. Voravuthikunchai,et al.  The mode of antistaphylococcal action of Eleutherine americana. , 2009, FEMS immunology and medical microbiology.

[36]  M. Lacroix,et al.  Mechanism of action of Spanish oregano, Chinese cinnamon, and savory essential oils against cell membranes and walls of Escherichia coli O157:H7 and Listeria monocytogenes. , 2006, Journal of food protection.

[37]  Emma Stirling,et al.  Food fears: a national survey on the attitudes of Australian adults about the safety and quality of food. , 2004, Asia Pacific journal of clinical nutrition.

[38]  R. Moezelaar,et al.  The Phenolic Hydroxyl Group of Carvacrol Is Essential for Action against the Food-Borne Pathogen Bacillus cereus , 2002, Applied and Environmental Microbiology.

[39]  J. Abrini,et al.  Investigation of functional and morphological changes in Pseudomonas aeruginosa and Staphylococcus aureus cells induced by Origanum compactum essential oil , 2009, Journal of applied microbiology.

[40]  E. Smid,et al.  Adaptation of the food-borne pathogen Bacillus cereus to carvacrol , 2000, Archives of Microbiology.

[41]  J Xu,et al.  The antibacterial mechanism of carvacrol and thymol against Escherichia coli , 2008, Letters in applied microbiology.

[42]  Hendrik N.J. Schifferstein,et al.  Health-related determinants of organic food consumption in the Netherlands. , 1998 .

[43]  P. Chalier,et al.  Antimicrobial activity of carvacrol related to its chemical structure , 2006, Letters in applied microbiology.

[44]  J. Warmington,et al.  The mode of antimicrobial action of the essential oil of Melaleuca alternifolia (tea tree oil) , 2000, Journal of applied microbiology.

[45]  T. Riley,et al.  Antimicrobial activity of essential oils and other plant extracts , 1999, Journal of applied microbiology.

[46]  J. L. T. Tjeerdsma-van Bokhoven,et al.  Structural requirements for the antimicrobial activity of carvacrol. , 2006, Journal of agricultural and food chemistry.

[47]  H. Nikaido,et al.  Prevention of drug access to bacterial targets: permeability barriers and active efflux. , 1994, Science.

[48]  N. Heredia,et al.  Extracts of Edible and Medicinal Plants Damage Membranes of Vibrio cholerae , 2010, Applied and Environmental Microbiology.

[49]  M. Gasson,et al.  Mode of antimicrobial action of vanillin against Escherichia coli, Lactobacillus plantarum and Listeria innocua , 2004, Journal of applied microbiology.

[50]  Hartland,et al.  Tea tree oil causes K+ leakage and inhibits respiration in Escherichia coli , 1998, Letters in applied microbiology.

[51]  William E Bentley,et al.  Quorum sensing and bacterial cross-talk in biotechnology. , 2004, Current opinion in biotechnology.

[52]  R. Holley,et al.  Disruption of Escherichia coli, Listeria monocytogenes and Lactobacillus sakei cellular membranes by plant oil aromatics. , 2006, International journal of food microbiology.

[53]  M. Hume,et al.  Effect of Origanum chemotypes on broiler intestinal bacteria. , 2014, Poultry science.

[54]  F. Husain,et al.  Inhibition of quorum sensing regulated bacterial functions by plant essential oils with special reference to clove oil , 2009, Letters in applied microbiology.

[55]  J. Hammitt,et al.  Perceived Risks of Conventional and Organic Produce: Pesticides, Pathogens, and Natural Toxins , 2001, Risk analysis : an official publication of the Society for Risk Analysis.

[56]  Todd R Callaway,et al.  Orange peel products can reduce Salmonella populations in ruminants. , 2011, Foodborne pathogens and disease.

[57]  J. Molnár,et al.  Inhibition of quorum‐sensing signals by essential oils , 2010, Phytotherapy research : PTR.

[58]  H. Chun,et al.  Immunomodulatory properties of dietary plum on coccidiosis. , 2008, Comparative immunology, microbiology and infectious diseases.

[59]  M. Jakobsen,et al.  Five essential oils from aromatic plants of Cameroon: their antibacterial activity and ability to permeabilize the cytoplasmic membrane of Listeria innocua examined by flow cytometry , 2004, Letters in applied microbiology.

[60]  Yoshihiro Inoue,et al.  Effects of Two Terpene Alcohols on the Antibacterial Activity and the Mode of Action of Farnesol against Staphylococcus aureus , 2008, Molecules.

[61]  G. González-Aguilar,et al.  Oregano essential oil-pectin edible films as anti-quorum sensing and food antimicrobial agents , 2014, Front. Microbiol..

[62]  K. Beauchemin,et al.  Effects of essential oils and their components on in vitro rumen microbial fermentation , 2007 .

[63]  B. Mee,et al.  Mechanism of Action of Melaleuca alternifolia (Tea Tree) Oil on Staphylococcus aureus Determined by Time-Kill, Lysis, Leakage, and Salt Tolerance Assays and Electron Microscopy , 2002, Antimicrobial Agents and Chemotherapy.

[64]  C. Bridts,et al.  Use of fluorescent dyes in the determination of adherence of human leucocytes to endothelial cells and the effect of fluorochromes on cellular function. , 1994, Journal of immunological methods.

[65]  B. Bassler,et al.  Quorum sensing in bacteria. , 2001, Annual review of microbiology.

[66]  M. Tsimidou,et al.  Composition and antioxidant activity of essential oils from Oregano plants grown wild in Greece , 1993 .

[67]  D. Bravo,et al.  Effects of dietary plant-derived phytonutrients on the genome-wide profiles and coccidiosis resistance in the broiler chickens , 2011, BMC proceedings.

[68]  M. Urdaci,et al.  Use of rosemary, oregano, and a commercial blend of essential oils in broiler chickens: in vitro antimicrobial activities and effects on growth performance. , 2012, Journal of animal science.