Transgenic Expression of Entire Hepatitis B Virus in Mice Induces Hepatocarcinogenesis Independent of Chronic Liver Injury
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S. Kakar | E. Huang | Q. Wang | M. Hanes | Limin Liu | Zhongxia Qi | Jingwei Yu | J. Ou | Bing Na | Zhiming Huang | Yong-jun Tian | Cheng‐Chan Lu | T. Yen | Yongjun Tian | Qian Wang | Martha A. Hanes | Eric J. Huang | J.-H. James Ou | T. S. B. Yen
[1] Bin Li,et al. S-Nitrosylation from GSNOR Deficiency Impairs DNA Repair and Promotes Hepatocarcinogenesis , 2010, Science Translational Medicine.
[2] R. Behringer,et al. Karyotyping mouse cells. , 2008, CSH protocols.
[3] D. Yergeau,et al. Injection-mediated transposon transgenesis in Xenopus tropicalis and the identification of integration sites by modified extension primer tag selection (EPTS) linker-mediated PCR , 2007, Nature Protocols.
[4] P. Walter,et al. Signal integration in the endoplasmic reticulum unfolded protein response , 2007, Nature Reviews Molecular Cell Biology.
[5] A. Protopopov,et al. The Differentiation and Stress Response Factor XBP-1 Drives Multiple Myeloma Pathogenesis , 2007, Cancer cell.
[6] J. Ou,et al. Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice , 2007, Hepatology.
[7] D. Scheuner,et al. ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth , 2005, The EMBO journal.
[8] K. Mori,et al. Activation of Hepatitis B Virus S Promoter by a Cell Type-Restricted IRE1-Dependent Pathway Induced by Endoplasmic Reticulum Stress , 2005, Molecular and Cellular Biology.
[9] Candy S. Lee,et al. Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[10] C. Epstein,et al. CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life , 2005, Oncogene.
[11] R. Kaufman,et al. ER stress and the unfolded protein response. , 2005, Mutation research.
[12] L. Hendershot,et al. The role of the unfolded protein response in tumour development: friend or foe? , 2004, Nature Reviews Cancer.
[13] A. Koong,et al. XBP1 Is Essential for Survival under Hypoxic Conditions and Is Required for Tumor Growth , 2004, Cancer Research.
[14] G. Raimondo,et al. Non-sequencing molecular approaches to identify preS2-defective hepatitis B virus variants proved to be associated with severe liver diseases. , 2004, Journal of hepatology.
[15] J. Bruix,et al. Focus on hepatocellular carcinoma. , 2004, Cancer cell.
[16] A. V. Smirnov,et al. High Prevalence of Hepatitis B Virus Pre-S Mutant in Countries Where It Is Endemic and Its Relationship with Genotype and Chronicity , 2003, Journal of Clinical Microbiology.
[17] M. Matsuda,et al. Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis , 2003, International journal of cancer.
[18] R. Jordan,et al. Molecular viral oncology of hepatocellular carcinoma , 2003, Oncogene.
[19] Hans Clevers,et al. Caught up in a Wnt storm: Wnt signaling in cancer. , 2003, Biochimica et biophysica acta.
[20] B. Ahn,et al. Cellular vacuolization and apoptosis induced by hepatitis B virus large surface protein , 2002, Hepatology.
[21] R. Kodell,et al. Survival characteristics and age-adjusted disease incidences in C57BL/6 mice fed a commonly used cereal-based diet modulated by dietary restriction. , 2002, The journals of gerontology. Series A, Biological sciences and medical sciences.
[22] Wenjie Tan,et al. Enhancement of Hepatitis B Virus Replication by Its X Protein in Transgenic Mice , 2002, Journal of Virology.
[23] W. Gerlich,et al. Hypermodification and immune escape of an internally deleted middle-envelope (M) protein of frequent and predominant hepatitis B virus variants. , 2002, Virology.
[24] K. Mori,et al. XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor , 2001, Cell.
[25] R. Pestell,et al. Activating Transcription Factor 3 Induces DNA Synthesis and Expression of Cyclin D1 in Hepatocytes* , 2001, The Journal of Biological Chemistry.
[26] Y. Shyr,et al. Hepatocellular carcinoma results from chronic cyclin D1 overexpression in transgenic mice. , 2001, Cancer research.
[27] H. Lei,et al. Identification of a pre‐S2 mutant in hepatocytes expressing a novel marginal pattern of surface antigen in advanced diseases of chronic hepatitis B virus infection , 2000, Journal of gastroenterology and hepatology.
[28] M. Buendia,et al. Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[29] F. Chisari,et al. Immune Pathogenesis of Hepatocellular Carcinoma , 1998, The Journal of experimental medicine.
[30] C. Fan,et al. Steatohepatitis, Spontaneous Peroxisome Proliferation and Liver Tumors in Mice Lacking Peroxisomal Fatty Acyl-CoA Oxidase , 1998, The Journal of Biological Chemistry.
[31] T. Yen,et al. Activation of hepatitis B virus S promoter by the viral large surface protein via induction of stress in the endoplasmic reticulum , 1997, Journal of virology.
[32] Amy S. Lee,et al. Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[33] T. Yen,et al. Intracellular retention of surface protein by a hepatitis B virus mutant that releases virion particles , 1996, Journal of virology.
[34] F. Chisari,et al. High-level hepatitis B virus replication in transgenic mice , 1995, Journal of virology.
[35] K. Koike,et al. High‐level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice , 1994, Hepatology.
[36] T. Yen,et al. Dysregulated surface gene expression from disrupted hepatitis B virus genomes , 1993, Journal of virology.
[37] H. Tsukuma,et al. Risk factors for hepatocellular carcinoma among patients with chronic liver disease. , 1993, The New England journal of medicine.
[38] P. Galle,et al. Infectious hepatitis B virus variant defective in pre-S2 protein expression in a chronic carrier. , 1993, Virology.
[39] G. Jay,et al. HBx gene of hepatitis B virus induces liver cancer in transgenic mice , 1991, Nature.
[40] J. Miyazaki,et al. Production and Effect of Infectious Dane Particles in Transgenic Mice , 1991, Japanese journal of cancer research : Gann.
[41] T. Yen,et al. The ubiquitous transcription factor Oct-1 and the liver-specific factor HNF-1 are both required to activate transcription of a hepatitis B virus promoter , 1991, Molecular and cellular biology.
[42] D. Ganem,et al. The role of envelope proteins in hepatitis B virus assembly. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[43] T. Yen,et al. Differential regulation of the hepatitis B virus surface gene promoters by a second viral enhancer. , 1990, Journal of Biological Chemistry.
[44] J. Butel,et al. Hepatitis B virus transactivator X protein is not tumorigenic in transgenic mice , 1990, Journal of virology.
[45] R. Palmiter,et al. Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice , 1989, Cell.
[46] R. Palmiter,et al. Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[47] K. Reifenberg,et al. Long-term expression of the hepatitis B virus core-e- and X-proteins does not cause pathologic changes in transgenic mice. , 1997, Journal of hepatology.
[48] Standard karyotype of the mouse, Mus musculus. , 1972, The Journal of heredity.
[49] T. Roderick. Committee on Standard Genetic Nomenclature for Mice: Standard karyotype of the mouse, Mus musculus. , 1972 .