Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells.
暂无分享,去创建一个
Huck-Hui Ng | H. Ng | Bo Feng | Jian-Chien Heng | Jia-Hui Ng | Jian-Chien Dominic Heng | Bo Feng | Jia-Hui Ng
[1] Richard A Young,et al. Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells. , 2008, Genes & development.
[2] Ian Chambers,et al. Estrogen-Related Receptor Beta Interacts with Oct4 To Positively Regulate Nanog Gene Expression , 2008, Molecular and Cellular Biology.
[3] Wenjun Guo,et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds , 2008, Nature Biotechnology.
[4] Tom Misteli,et al. Chromatin in pluripotent embryonic stem cells and differentiation , 2006, Nature Reviews Molecular Cell Biology.
[5] Anne E Kwitek,et al. Multifactorial genetics: Rat genetics: attachign physiology and pharmacology to the genome , 2002, Nature Reviews Genetics.
[6] J. Rossant. Stem Cells and Early Lineage Development , 2008, Cell.
[7] Sheng Ding,et al. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. , 2009, Cell stem cell.
[8] T. Graf,et al. Stepwise Reprogramming of B Cells into Macrophages , 2004, Cell.
[9] Megan F. Cole,et al. Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells , 2005, Cell.
[10] A. Consiglio,et al. Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes , 2008, Nature Biotechnology.
[11] George Q. Daley,et al. Reprogramming of human somatic cells to pluripotency with defined factors , 2008, Nature.
[12] M. Araúzo-Bravo,et al. Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors , 2008, Nature.
[13] Keith D. Robertson,et al. DNA Methylation Inhibitor 5-Aza-2′-Deoxycytidine Induces Reversible Genome-Wide DNA Damage That Is Distinctly Influenced by DNA Methyltransferases 1 and 3B , 2007, Molecular and Cellular Biology.
[14] C. Hsieh,et al. Germline Competent Embryonic Stem Cells Derived from Rat Blastocysts , 2008, Cell.
[15] A. Bradley,et al. A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells. , 2009, Genome research.
[16] M. Trotter,et al. Derivation of pluripotent epiblast stem cells from mammalian embryos , 2007, Nature.
[17] K. Plath,et al. Generation of human induced pluripotent stem cells from dermal fibroblasts , 2008, Proceedings of the National Academy of Sciences.
[18] Sheng Ding,et al. A chemical approach to stem-cell biology and regenerative medicine , 2008, Nature.
[19] P. Mali,et al. Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts , 2008, Stem cells.
[20] Xi Chen,et al. Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. , 2007, Genes & development.
[21] Akihiko Okuda,et al. The Gene for the Embryonic Stem Cell Coactivator UTF1 Carries a Regulatory Element Which Selectively Interacts with a Complex Composed of Oct-3/4 and Sox-2 , 1999, Molecular and Cellular Biology.
[22] J. Nichols,et al. Klf4 reverts developmentally programmed restriction of ground state pluripotency , 2009, Development.
[23] G. Daley,et al. Selective Blockade of MicroRNA Processing by Lin28 , 2008, Science.
[24] Xiaolei Yin,et al. Two supporting factors greatly improve the efficiency of human iPSC generation. , 2008, Cell stem cell.
[25] B. Doble,et al. The ground state of embryonic stem cell self-renewal , 2008, Nature.
[26] Stuart H. Orkin,et al. A protein interaction network for pluripotency of embryonic stem cells , 2006, Nature.
[27] Marius Wernig,et al. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells , 2007, Nature Biotechnology.
[28] Wei Wang,et al. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells , 2009, Nature.
[29] G. Ming,et al. G9a and Jhdm2a Regulate Embryonic Stem Cell Fusion‐Induced Reprogramming of Adult Neural Stem Cells , 2008, Stem cells.
[30] Gu Weijun,et al. Strategies and new developments in the generation of pluripotent stem cells. , 2009 .
[31] Daniel J. Hoeppner,et al. Global transcription in pluripotent embryonic stem cells. , 2008, Cell stem cell.
[32] N. D. Clarke,et al. Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells , 2008, Cell.
[33] T. Ichisaka,et al. Generation of germline-competent induced pluripotent stem cells , 2007, Nature.
[34] Jennifer Nichols,et al. Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition , 2008, PLoS biology.
[35] J. Nichols,et al. Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells. , 1999, Developmental biology.
[36] T. Misteli,et al. Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. , 2006, Developmental cell.
[37] Thomas Lufkin,et al. Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb , 2009, Nature Cell Biology.
[38] Takashi Aoi,et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts , 2008, Nature Biotechnology.
[39] J. Utikal,et al. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. , 2007, Cell stem cell.
[40] R. Young,et al. Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming , 2008, Cell.
[41] Shinya Yamanaka,et al. Pluripotency and nuclear reprogramming , 2008, Philosophical Transactions of the Royal Society B: Biological Sciences.
[42] Wenjun Guo,et al. Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2 , 2008, Nature Biotechnology.
[43] P. Greengard,et al. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor , 2004, Nature Medicine.
[44] Marius Wernig,et al. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. , 2008, Cell stem cell.
[45] J. Thomson,et al. Pluripotent stem cell lines. , 2008, Genes & development.
[46] Tao Wang,et al. Esrrb Activates Oct4 Transcription and Sustains Self-renewal and Pluripotency in Embryonic Stem Cells* , 2008, Journal of Biological Chemistry.
[47] J. Utikal,et al. Induced Pluripotent Stem Cells Generated Without Viral Integration , 2008, Science.
[48] Douglas A. Melton,et al. In vivo reprogramming of adult pancreatic exocrine cells to β-cells , 2008, Nature.
[49] Hui Li,et al. Generation of induced pluripotent stem cell lines from adult rat cells. , 2009, Cell stem cell.
[50] Fei Yi,et al. Tcf3 Functions as a Steady‐State Limiter of Transcriptional Programs of Mouse Embryonic Stem Cell Self‐Renewal , 2008, Stem cells.
[51] Austin G Smith,et al. Capturing Pluripotency , 2008, Cell.
[52] Mike J. Mason,et al. Role of the Murine Reprogramming Factors in the Induction of Pluripotency , 2009, Cell.
[53] Meng Liu,et al. Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. , 2008, Cell stem cell.
[54] R. Stewart,et al. Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.
[55] Walter Birchmeier,et al. Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. , 2008, Genes & development.
[56] Austin G Smith,et al. Capture of Authentic Embryonic Stem Cells from Rat Blastocysts , 2008, Cell.
[57] Sheng Ding,et al. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. , 2008, Cell stem cell.
[58] D. Melton,et al. Extreme makeover: converting one cell into another. , 2008, Cell stem cell.
[59] K. Hochedlinger,et al. Guidelines and techniques for the generation of induced pluripotent stem cells. , 2008, Cell stem cell.
[60] H. Cedar,et al. G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis , 2006, Nature Cell Biology.
[61] S. Yamanaka,et al. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.
[62] Shinya Yamanaka,et al. Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors , 2008, Science.
[63] S. Nishikawa,et al. A ROCK inhibitor permits survival of dissociated human embryonic stem cells , 2007, Nature Biotechnology.
[64] Paul Pavlidis,et al. Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells. , 2009, Cell stem cell.
[65] B. Thiers. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2008 .
[66] H. Schöler,et al. A combined chemical and genetic approach for the generation of induced pluripotent stem cells. , 2008, Cell stem cell.
[67] P. ’. ‘t Hoen,et al. Induced pluripotency with endogenous and inducible genes. , 2008, Experimental cell research.
[68] Radu Dobrin,et al. Dissecting self-renewal in stem cells with RNA interference , 2006, Nature.
[69] A. Smith,et al. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. , 1998, Genes & development.
[70] R. Jaenisch,et al. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state , 2007, Nature.
[71] Austin G Smith,et al. FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment , 2007, Development.
[72] Jun Qin,et al. Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells , 2008, Nature Cell Biology.
[73] A. Hampl,et al. Expression and Potential Role of Fibroblast Growth Factor 2 and Its Receptors in Human Embryonic Stem Cells , 2005, Stem cells.
[74] C. Lengner,et al. The pluripotency regulator Oct4: A role in somatic stem cells? , 2008, Cell cycle.
[75] J. M. Thomson,et al. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. , 2008, RNA.
[76] Hitoshi Niwa,et al. How is pluripotency determined and maintained? , 2007, Development.
[77] Donald C. Chang,et al. Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state. , 2008, RNA.
[78] T. Mikkelsen,et al. Dissecting direct reprogramming through integrative genomic analysis , 2008, Nature.
[79] Takashi Aoi,et al. Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells , 2008, Science.
[80] S. Orkin,et al. An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells , 2008, Cell.
[81] J. Lieberman,et al. let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells , 2007, Cell.
[82] R. Yeh,et al. MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. , 2008, Cell stem cell.
[83] Hsu-hsin Chen,et al. The Growth Factor Environment Defines Distinct Pluripotent Ground States in Novel Blastocyst-Derived Stem Cells , 2008, Cell.
[84] H. Cedar,et al. De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes , 2008, Nature Structural &Molecular Biology.
[85] Richard A Young,et al. Wnt signaling promotes reprogramming of somatic cells to pluripotency. , 2008, Cell stem cell.
[86] X. Chen,et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells , 2006, Nature Genetics.
[87] M. Cosma,et al. Periodic activation of Wnt/beta-catenin signaling enhances somatic cell reprogramming mediated by cell fusion. , 2008, Cell stem cell.
[88] J. Nichols,et al. BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3 , 2003, Cell.
[89] David G. Melvin,et al. Chromosomal transposition of PiggyBac in mouse embryonic stem cells , 2008, Proceedings of the National Academy of Sciences.
[90] T. Ichisaka,et al. GENERATION OF GERMLINECOMPETENT INDUCED PLURIPOTENT STEM CELLS , 2007 .
[91] A. Sparks,et al. Identification of c-MYC as a target of the APC pathway. , 1998, Science.
[92] H. Ng,et al. T‐Cell Factor 3 Regulates Embryonic Stem Cell Pluripotency and Self‐Renewal by the Transcriptional Control of Multiple Lineage Pathways , 2008, Stem cells.
[93] R. McKay,et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells , 2007, Nature.
[94] J. Utikal,et al. Reprogramming of Neural Progenitor Cells into Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 Expression , 2008, Stem cells.
[95] Shulan Tian,et al. Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.
[96] Marcos J. Araúzo-Bravo,et al. Oct4-Induced Pluripotency in Adult Neural Stem Cells , 2009, Cell.
[97] K. Woltjen,et al. Virus free induction of pluripotency and subsequent excision of reprogramming factors , 2009, Nature.