Efficient Synthesis of Substituted 2-(4H-1,3-benzoxazin-2-yl)Phenols via a Pseudo Three-Component Reaction

An efficient pseudo three-component reaction between substituted 2-hydroxybenzaldehydes and ammonium acetate for the preparation of substituted 2-(4H-1,3-benzoxazin-2-yl)phenols in moderate to good yields (70-80%) was developed. The structure of a typical product was confirmed by X-ray crystallography.

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