Activated Charcoal in Medical Applications

Introduction Historical Background of Activated Charcoal Fundamentals of Activated Charcoal and the Adsorption Process Properties of Antidotal Charcoal The Nature of Drug Absorption, Distribution, and Elimination Basic Details of Pharmacokinetic Modeling Methods for Treating Poisoning and Drug Overdose The Design of Clinical Studies and Data Treatment Some Basic Aspects of Antidotal Charcoal The Classic Studies of Andersen Effects of Activated Charcoal on Major Classes of Drugs and Chemicals Effect of Charcoal on Other Classes of Drugs Effect of Administration Time, Food, and Gastric pH Effect of Multiple Doses of Charcoal Ipecac, Cathartics, and Charcoal: Interactions and Comparative Efficacies The Development of Palatable Formulations Hazards Associated with Antidotal Charcoal Use Effect of Charcoal on Various Inorganic Substances Effect of Charcoal on Endogenous Biochemicals Use of Charcoal to Treat Poisoning in Animals Reports from the Soviet Union Resins and Clays as Sorbents Other Medicinal Uses of Charcoal in Humans Other Biochemical and Biological Uses of Charcoal Summary