The NCI Thesaurus quality assurance life cycle

The National Cancer Institute Enterprise Vocabulary Services (NCI EVS) uses a wide range of quality assurance (QA) techniques to maintain and extend NCI Thesaurus (NCIt). NCIt is a reference terminology and biomedical ontology used in a growing number of NCI and other systems that extend from translational and basic research through clinical care to public information and administrative activities. Both automated and manual QA techniques are employed throughout the editing and publication cycle, which includes inserting and editing NCIt in NCI Metathesaurus. NCI EVS conducts its own additional periodic and ongoing content QA. External reviews, and extensive evaluation by and interaction with EVS partners and other users, have also played an important part in the QA process. There have always been tensions and compromises between meeting the needs of dependent systems and providing consistent and well-structured content; external QA and feedback have been important in identifying and addressing such issues. Currently, NCI EVS is exploring new approaches to broaden external participation in the terminology development and QA process.

[1]  J. Cimino.  Desiderata for Controlled Medical Vocabularies in the Twenty-First Century , 1998, Methods of Information in Medicine.

[2]  K. Buetow.  Cyberinfrastructure: Empowering a "Third Way" in Biomedical Research , 2005, Science.

[3]  Olivier Bodenreider,et al.  Auditing the NCI Thesaurus with Semantic Web Technologies , 2008, AMIA.

[4]  James J. Cimino,et al.  In defense of the Desiderata , 2005, Journal of Biomedical Informatics.

[5]  Nicolette de Keizer,et al.  Development and Application of a Framework for Maintenance of Medical Terminological Systems , 2008, Journal of the American Medical Informatics Association.

[6]  Sherri de Coronado,et al.  NCI Thesaurus: A semantic model integrating cancer-related clinical and molecular information , 2007, J. Biomed. Informatics.

[7]  Yue Wang,et al.  Research Paper: Auditing as Part of the Terminology Design Life Cycle , 2006, J. Am. Medical Informatics Assoc..

[8]  Mark S. Tuttle,et al.  NCI Thesaurus: Using Science-Based Terminology to Integrate Cancer Research Results , 2004, MedInfo.

[9]  Yehoshua Perl,et al.  Detecting Role Errors in the Gene Hierarchy of the NCI Thesaurus , 2008, Cancer informatics.

[10]  James A. Hendler,et al.  The National Cancer Institute's Thésaurus and Ontology , 2003, J. Web Semant..

[11]  Gilberto Fragoso,et al.  Enhancing Quality of Retrieval Through Concept Edit History , 2003, AMIA.

[12]  Gilberto Fragoso,et al.  caCORE version 3: Implementation of a model driven, service-oriented architecture for semantic interoperability , 2008, J. Biomed. Informatics.

[13]  W Ceusters,et al.  A Terminological and Ontological Analysis of the NCI Thesaurus , 2005, Methods of Information in Medicine.

[14]  Larry Wright,et al.  Overview and Utilization of the NCI Thesaurus , 2004, Comparative and functional genomics.

[15]  Scott Gustafson,et al.  caCORE: A common infrastructure for cancer informatics , 2003, Bioinform..

[16]  Jennifer Golbeck,et al.  Modeling a description logic vocabulary for cancer research , 2005, J. Biomed. Informatics.

[17]  Hua Min,et al.  Automated comparative auditing of NCIT genomic roles using NCBI , 2008, J. Biomed. Informatics.