Long-term results of transradial rotational atherectomy for heavily calcified coronary artery lesions

Objective: Percutaneous coronary intervention (PCI) for the heavily calcified coronary lesions remains a challenge, and the periprocedural complication rates of the transfemoral approach are high. This study was conducted to investigate the feasibility and long-term results of the transradial approach for rotational atherectomy (RA) prior to stent implantation via the transradial approach in patients with heavily calcified coronary artery lesions. Methods: RA followed by stent implantation via the transradial approach was performed in 47 patients with severely calcified coronary artery lesions in this retrospectively case-control study. The success rate of the procedure and the 3-year follow-up (36±7.5 months) results were analyzed. Results: RA with subsequent stent implantation or balloon angioplasty procedures were successfully performed in all cases. 6F guiding catheters were used in 45 cases, and 7F catheters were used in 2 patients. Rotablation was performed with a 1.25-mm burr in 29 cases, a 1.25-mm burr followed by a 1.5-mm burr in 17 patients, and a 1.75-mm burr in 1 patient. Percutaneous transluminal coronary angioplasty after RA was performed, followed by stent implantation in all 47 patients. Restenosis was found in 7 cases (7/38) at 13 months (13±3.6) and in 13 cases (13/28) at 36 months (36±7.5) after the procedure; 3 patients died during the 3-year follow-up. The post-procedure cumulative 3-year event-free survival rate was 78%. Conclusion: RA prior to stent implantation via the transradial approach is feasible and safe, the success rate is high, and long-term outcome is satisfactory in patients with heavily calcified lesions of the coronary artery.

[1]  B. Merkely,et al.  Clinical predictors of mortality following rotational atherectomy and stent implantation in high‐risk patients: A single center experience , 2015, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[2]  Wei Li,et al.  A Comparison of Transradial and Transfemoral Approaches for Percutaneous Coronary Intervention in Elderly Patients Based on a Propensity Score Analysis , 2015, Angiology.

[3]  C. Kaymaz,et al.  The effects of tirofiban infusion on clinical and angiographic outcomes of patients with STEMI undergoing primary PCI , 2014, Anatolian journal of cardiology.

[4]  Samin K. Sharma,et al.  Current status of rotational atherectomy. , 2014, JACC. Cardiovascular interventions.

[5]  I. Takamisawa,et al.  Rotational atherectomy followed by cutting-balloon plaque modification for drug-eluting stent implantation in calcified coronary lesions. , 2012, The Journal of invasive cardiology.

[6]  M. Kimura,et al.  Rotational atherectomy for fibro‐calcific coronary artery disease in drug eluting stent era: Procedural outcomes and angiographic follow‐up results , 2010, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[7]  S. Qiao,et al.  Comparison of immediate and followup results between transradial and transfemoral approach for percutaneous coronary intervention in true bifurcational lesions. , 2007, Chinese medical journal.

[8]  M. Mosseri,et al.  Impact of vessel calcification on outcomes after coronary stenting. , 2005, Cardiovascular revascularization medicine : including molecular interventions.

[9]  K. Yano,et al.  Effect of rotational atherectomy on the coronary microcirculation in patients with angina pectoris. , 2005, Journal of cardiology.

[10]  R. Choussat,et al.  Vascular complications and clinical outcome after coronary angioplasty with platelet IIb/IIIa receptor blockade. Comparison of transradial vs transfemoral arterial access. , 2000, European heart journal.

[11]  O. Rosales,et al.  Intracoronary adenosine administered during rotational atherectomy of complex lesions in native coronary arteries reduces the incidence of no-reflow phenomenon. , 1998, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[12]  W. O’Neill,et al.  Effect of Rotablator atherectomy and adjunctive balloon angioplasty on coronary blood flow. , 1997, Circulation.

[13]  P. Fitzgerald,et al.  Contribution of Localized Calcium Deposits to Dissection After Angioplasty: An Observational Study Using Intravascular Ultrasound , 1992, Circulation.

[14]  S. Redwood,et al.  Contemporary clinical outcomes of patients treated with or without rotational coronary atherectomy--an analysis of the UK central cardiac audit database. , 2014, International journal of cardiology.

[15]  F. Neumann,et al.  High-speed rotational atherectomy before paclitaxel-eluting stent implantation in complex calcified coronary lesions: the randomized ROTAXUS (Rotational Atherectomy Prior to Taxus Stent Treatment for Complex Native Coronary Artery Disease) trial. , 2013, JACC. Cardiovascular interventions.

[16]  M. Valdés Chávarri,et al.  Percutaneous coronary intervention in heavily calcified lesions using rotational atherectomy and paclitaxel-eluting stents: outcomes at one year. , 2010, Revista espanola de cardiologia.