Human and Porcine Hepatitis E Virus Strains, United Kingdom

We describe a case of acquired infection of a strain of hepatitis E virus (HEV)with a 100% amino acid identity to the analogous region in strains of HEV circulating in a United Kingdom pig herd. This case further supports the theory that autochthonous HEV infection in industrialized countries is zoonotic.

[1]  R. Girones,et al.  Evidence for the presence of hepatitis E virus in pigs in the United Kingdom , 2004, Veterinary Record.

[2]  T. Nishizawa,et al.  Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be food-borne, as suggested by the presence of hepatitis E virus in pig liver as food. , 2003, The Journal of general virology.

[3]  S. Mishiro,et al.  Zoonotic transmission of hepatitis E virus from deer to human beings , 2003, The Lancet.

[4]  T. Nishizawa,et al.  Characterization of Japanese swine and human hepatitis E virus isolates of genotype IV with 99 % identity over the entire genome. , 2003, The Journal of general virology.

[5]  H. Dalton,et al.  The “jaundice hotline” for the rapid assessment of patients with jaundice , 2002, BMJ : British Medical Journal.

[6]  S. Emerson,et al.  Prevalence of Antibodies to Hepatitis E Virus in Veterinarians Working with Swine and in Normal Blood Donors in the United States and Other Countries , 2002, Journal of Clinical Microbiology.

[7]  M. Peiris,et al.  Occurrence of hepatitis E virus IgM, low avidity IgG serum antibodies, and viremia in sporadic cases of non‐A, ‐B, and ‐C acute hepatitis , 2002, Journal of medical virology.

[8]  T. Nishizawa,et al.  Analysis of the complete genome of indigenous swine hepatitis E virus isolated in Japan. , 2001, Biochemical and biophysical research communications.

[9]  Yufei Wang,et al.  Partial sequence analysis of indigenous hepatitis E virus isolated in the United Kingdom , 2001, Journal of medical virology.

[10]  Yi‐Hsiang Huang,et al.  Clinical and epidemiological implications of swine hepatitis E virus infection , 2000, Journal of medical virology.

[11]  S. Emerson,et al.  A novel virus in swine is closely related to the human hepatitis E virus. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[12]  S. Stoszek,et al.  Hepatitis E: an emerging infectious disease. , 1999, Epidemiologic reviews.

[13]  S. Emerson,et al.  Experimental infection of pigs with the newly identified swine hepatitis E virus (swine HEV), but not with human strains of HEV , 1998, Archives of Virology.