Guidelines for the economic analysis of a telematic platform for Parkinson's disease monitoring

PERFORM (A sophisticated multi-parametric system FOR the continuous effective assessment and monitoring of motor status in Parkinson's disease and other neurodegenerative diseases) is an European project which aim is to provide doctors with a telematic tool for the remote monitoring of Parkinson's disease (PD) patients at their homes. The technical performance of PERFORM has been addressed in previous publications. The aim of this work is to introduce the best well-known methodologies and indicators used in the health economics field, normally linked to the assessment of drugs or devices, and provide a set of guidelines for the use of these methodologies in the assessment of telehealth systems focused on PD patients. PD will also be introduced in economic terms, i.e. burden and cost of PD. This study will be done with special emphasis in European countries.

[1]  B. Saraceno,et al.  The WHO World Health Report 2001 on mental health , 2002, Epidemiologia e Psichiatria Sociale.

[2]  R. Verbrugge,et al.  Impact of Medication Adherence on Hospitalization Risk and Healthcare Cost , 2005, Medical care.

[3]  Jeffrey M. Hausdorff,et al.  Falls in outpatients with Parkinson's disease: frequency, impact and identifying factors. , 2005, Journal of neurology.

[4]  M. Drummond,et al.  Health Care Technology: Effectiveness, Efficiency and Public Policy@@@Methods for the Economic Evaluation of Health Care Programmes , 1988 .

[5]  J. Summers,et al.  The pathogenesis of gait hypokinesia in Parkinson's disease. , 1994, Brain : a journal of neurology.

[6]  R. Chisin.  Cost-Effectiveness Analysis , 2009, Journal of Nuclear Medicine.

[7]  H. Wittchen,et al.  Cost of anxiety disorders in Europe , 2005, European journal of neurology.

[8]  D. Huse,et al.  Burden of illness in Parkinson's disease , 2005, Movement disorders : official journal of the Movement Disorder Society.

[9]  Jeffrey M. Hausdorff,et al.  Falls and freezing of gait in Parkinson's disease: A review of two interconnected, episodic phenomena , 2004, Movement disorders : official journal of the Movement Disorder Society.

[10]  Ann Ashburn,et al.  A meta‐analysis of six prospective studies of falling in Parkinson's disease , 2007, Movement disorders : official journal of the Movement Disorder Society.

[11]  A. Elixhauser,et al.  Estimating Costs in the Economic Evaluation of Medical Technologies , 1990, International Journal of Technology Assessment in Health Care.

[12]  R Robinson,et al.  Costs and cost-minimisation analysis. , 1993, BMJ.

[13]  R B Wallace,et al.  The health burdens of Parkinson's disease , 1998, Movement disorders : official journal of the Movement Disorder Society.

[14]  Thomas Müller-Bohn,et al.  Cost-Benefit Analysis , 2015 .

[15]  C. Ward.  What contributes to quality of life in patients with Parkinson's disease? , 2000, Journal of neurology, neurosurgery, and psychiatry.

[16]  P. Martínez Martín,et al.  Burden of disease related to Parkinson's disease in Spain in the year 2000 , 2005, Movement disorders : official journal of the Movement Disorder Society.

[17]  C. Naylor,et al.  Burden of parkinsonism: A population‐based study , 2003, Movement disorders : official journal of the Movement Disorder Society.

[18]  H Helenius,et al.  The quality of life in Parkinson's disease , 2000, Movement disorders : official journal of the Movement Disorder Society.

[19]  Dimitrios I. Fotiadis,et al.  Assessment of Tremor Activity in the Parkinson’s Disease Using a Set of Wearable Sensors , 2012, IEEE Transactions on Information Technology in Biomedicine.

[20]  Michael T French,et al.  Economic evaluation of telemedicine: review of the literature and research guidelines for benefit-cost analysis. , 2009, Telemedicine journal and e-health : the official journal of the American Telemedicine Association.

[21]  Jan J. Barendregt,et al.  Disability weights for diseases in the Netherlands , 1997 .

[22]  L. Findley,et al.  The economic impact of Parkinson's disease. , 2007, Parkinsonism & related disorders.

[23]  Joseph S. Pliskin,et al.  Utility Functions for Life Years and Health Status , 1980, Oper. Res..

[24]  D. Coyle,et al.  The economic evaluation of pharmacotherapies for Parkinson's disease. , 2003, Parkinsonism & related disorders.

[25]  D. Feeny,et al.  Utilities and Quality-Adjusted Life Years , 1989, International Journal of Technology Assessment in Health Care.

[26]  V. Laulumaa,et al.  Economic burden and quality of life impairment increase with severity of PD. , 2003, Parkinsonism & related disorders.

[27]  M. Leonardi,et al.  Quality of life in Parkinson`s Disease , 2012, Journal of medicine and life.

[28]  William S. Cartwright,et al.  Methods for the economic evaluation of health care programmes, second edition. By Michael F. Drummond, Bernie O'Brien, Greg L. Stoddart, George W. Torrance. Oxford: Oxford University Press, 1997. , 1999 .

[29]  María Teresa Arredondo,et al.  Gait assessment in Parkinson's disease patients through a network of wearable accelerometers in unsupervised environments , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[30]  María Teresa Arredondo,et al.  Assessment of bradykinesia in Parkinson's disease patients through a multi-parametric system , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[31]  A. Nicholls.  Cost-utility analysis. , 1993, BMJ.

[32]  U. Siebert,et al.  Cost of Parkinson's disease in Europe , 2005, European journal of neurology.

[33]  J. Olesen,et al.  Cost of disorders of the brain in Europe , 2005, European journal of neurology.

[34]  M. Azari,et al.  Effects of intraperitoneal injection of Rofecoxib in a mouse model of ALS , 2005, European journal of neurology.

[35]  Dimitrios I. Fotiadis,et al.  Automated Levodopa-induced dyskinesia assessment , 2010, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.

[36]  A. D. Benetti,et al.  Preventing disease through healthy environments: towards an estimate of the environmental burden of disease , 2007 .

[37]  Kathryn Coyle,et al.  Home telehealth for chronic disease management: A systematic review and an analysis of economic evaluations , 2009, International Journal of Technology Assessment in Health Care.

[38]  Penny Jennett,et al.  The need for economic evaluation of telemedicine to evolve: the experience in Alberta, Canada. , 2004, Telemedicine journal and e-health : the official journal of the American Telemedicine Association.