Estimating Resting Core Temperature Using Heart Rate

ECTemp™ is a heart rate (HR)-based core temperature (CT) estimation algorithm mainly used as a real-time thermal-work strain indicator in military populations. ECTemp™ may also be valuable for resting CT estimation, which is critical for circadian rhythm research. This investigation developed and incorporated a sigmoid equation into ECTemp™ to better estimate resting CT. HR and CT data were collected over two calorimeter test trials from 16 volunteers (age, 23 ± 3 yrs; height, 1.72 ± 0.07 m; body mass, 68.5 ± 8.1 kg) during periods of sleep and inactivity. Half of the test trials were combined with ECTemp™’s original development dataset to train the new sigmoid model while the other was used for model validation. Models were compared by their estimation accuracy and precision. While both models produced accurate CT estimates, the sigmoid model had a smaller bias (−0.04 ± 0.26°C vs. −0.19 ± 0.29°C) and root mean square error (RMSE; 0.26°C vs. 0.35°C). ECTemp™ is a validated HR-based resting CT estimation algorithm. The new sigmoid equation corrects lower CT estimates while producing nearly identical estimates to the original quadratic equation at higher CT. The demonstrated accuracy of ECTemp™ encourages future research to explore the algorithm’s potential as a non-invasive means of tracking CT circadian rhythms.

[1]  Michael Koutsilieris,et al.  Circadian Rhythm Disruption in Cancer Biology , 2012, Molecular medicine.

[2]  Aaron J. E. Bach,et al.  The Systematic Bias of Ingestible Core Temperature Sensors Requires a Correction by Linear Regression , 2017, Front. Physiol..

[3]  Adam W. Potter,et al.  Mathematical prediction of core body temperature from environment, activity, and clothing: The heat strain decision aid (HSDA). , 2017, Journal of thermal biology.

[4]  Agnes Psikuta,et al.  Prediction of human core body temperature using non-invasive measurement methods , 2013, International Journal of Biometeorology.

[5]  David P. Looney,et al.  Estimation of metabolic energy expenditure from core temperature using a human thermoregulatory model. , 2018, Journal of thermal biology.

[6]  Greg Welch,et al.  An Introduction to Kalman Filter , 1995, SIGGRAPH 2001.

[7]  F. J. Richards A Flexible Growth Function for Empirical Use , 1959 .

[8]  J. Karvonen,et al.  Heart Rate and Exercise Intensity During Sports Activities , 1988, Sports medicine.

[9]  W. Rietveld,et al.  Circadian rhythms and masking: an overview. , 1993, Chronobiology international.

[10]  George Havenith,et al.  Prediction of Core Body Temperature from Multiple Variables. , 2015, The Annals of occupational hygiene.

[11]  M J Buller,et al.  Telemetry pill measurement of core temperature in humans during active heating and cooling. , 1998, Medicine and science in sports and exercise.

[12]  Victoria L Richmond,et al.  The effect of cool water ingestion on gastrointestinal pill temperature. , 2008, Medicine and science in sports and exercise.

[13]  C. Johnson,et al.  Circadian Disruption Leads to Insulin Resistance and Obesity , 2013, Current Biology.

[14]  J. Stephenson,et al.  Core temperature: Some shortcomings of rectal temperature measurements , 1977, Physiology & Behavior.

[15]  Odest Chadwicke Jenkins,et al.  Estimation of human core temperature from sequential heart rate observations , 2013, Physiological measurement.

[16]  Russell G Foster,et al.  Sleep and circadian rhythm disruption in neuropsychiatric illness , 2013, Current Opinion in Neurobiology.

[17]  William J. Tharion,et al.  Acceptability and Usability of an Ambulatory Health Monitoring System for Use by Military Personnel , 2013 .

[18]  William J. Tharion,et al.  Real-time core body temperature estimation from heart rate for first responders wearing different levels of personal protective equipment , 2015, Ergonomics.

[19]  Seungbum Hong,et al.  Estimation of Circadian Body Temperature Rhythm Based on Heart Rate in Healthy, Ambulatory Subjects , 2017, IEEE Journal of Biomedical and Health Informatics.

[20]  D. Weinert,et al.  Activity, sleep and ambient light have a different impact on circadian blood pressure, heart rate and body temperature rhythms , 2017, Chronobiology international.

[21]  J. M. Mckay,et al.  Physiological tolerance to uncompensable heat stress: effects of exercise intensity, protective clothing, and climate. , 1994, Journal of applied physiology.

[22]  J D Hardy,et al.  Comfort and thermal sensations and associated physiological responses at various ambient temperatures. , 1967, Environmental research.

[23]  G. Cornelissen,et al.  Procedures for numerical analysis of circadian rhythms , 2007, Biological rhythm research.