Identification of the histidine residues involved in substrate recognition by a rat H+/peptide cotransporter, PEPT1

[1]  H. Saito,et al.  Molecular cloning and tissue distribution of rat peptide transporter PEPT2. , 1996, Biochimica et biophysica acta.

[2]  S. Takenoshita,et al.  Immuno-localization of H+/peptide cotransporter in rat digestive tract. , 1996, Biochemical and biophysical research communications.

[3]  D. Loo,et al.  Mechanisms of the Human Intestinal H-coupled Oligopeptide Transporter hPEPT1 (*) , 1996, The Journal of Biological Chemistry.

[4]  D. Markovich,et al.  Expression cloning and functional characterization of the kidney cortex high-affinity proton-coupled peptide transporter. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[5]  H. Saito,et al.  Cloning and characterization of a rat H+/peptide cotransporter mediating absorption of beta-lactam antibiotics in the intestine and kidney. , 1995, The Journal of pharmacology and experimental therapeutics.

[6]  V. Ganapathy,et al.  Differential Recognition of β-Lactam Antibiotics by Intestinal and Renal Peptide Transporters, PEPT 1 and PEPT 2 (*) , 1995, The Journal of Biological Chemistry.

[7]  P. Swaan,et al.  Molecular mechanism for the relative binding affinity to the intestinal peptide carrier. Comparison of three ACE-inhibitors: enalapril, enalaprilat, and lisinopril. , 1995, Biochimica et biophysica acta.

[8]  M. Hediger,et al.  Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney. , 1995, Biochimica et biophysica acta.

[9]  M. Hediger,et al.  Human Intestinal H+/Peptide Cotransporter , 1995, The Journal of Biological Chemistry.

[10]  H. Saito,et al.  Transcellular transport of oral cephalosporins in human intestinal epithelial cells, Caco-2: interaction with dipeptide transport systems in apical and basolateral membranes. , 1994, The Journal of pharmacology and experimental therapeutics.

[11]  M. Romero,et al.  Expression cloning of a mammalian proton-coupled oligopeptide transporter , 1994, Nature.

[12]  C. Brewer Chapter 11 Cytomegalovirus Plasmid Vectors for Permanent Lines of Polarized Epithelial Cells , 1994 .

[13]  C Mrowietz,et al.  Improved in vitro rheological system for studying the effect of fluid shear stress on cultured cells. , 1993, The American journal of physiology.

[14]  H. Saito,et al.  Transepithelial transport of oral cephalosporins by monolayers of intestinal epithelial cell line Caco-2: specific transport systems in apical and basolateral membranes. , 1992, The Journal of pharmacology and experimental therapeutics.

[15]  H. Saito,et al.  Transcellular transport of organic cation across monolayers of kidney epithelial cell line LLC-PK. , 1992, The American journal of physiology.

[16]  K. Inui,et al.  Effect of various chemical modifiers on H+ coupled transport of cephradine via dipeptide carriers in rabbit intestinal brush-border membranes: role of histidine residues. , 1989, The Journal of pharmacology and experimental therapeutics.

[17]  G. Amidon,et al.  Passive and carrier-mediated intestinal absorption components of captopril. , 1988, Journal of pharmaceutical sciences.

[18]  M. Takano,et al.  H+ coupled transport of p.o. cephalosporins via dipeptide carriers in rabbit intestinal brush-border membranes: difference of transport characteristics between cefixime and cephradine. , 1988, The Journal of pharmacology and experimental therapeutics.

[19]  T. Terasaki,et al.  H+ gradient-dependent and carrier-mediated transport of cefixime, a new cephalosporin antibiotic, across brush-border membrane vesicles from rat small intestine. , 1987, The Journal of pharmacology and experimental therapeutics.

[20]  V. Ganapathy,et al.  Identification of histidyl and thiol groups at the active site of rabbit renal dipeptide transporter. , 1986, The Journal of biological chemistry.

[21]  M. Takano,et al.  H+ coupled uphill transport of aminocephalosporins via the dipeptide transport system in rabbit intestinal brush-border membranes. , 1986, The Journal of biological chemistry.

[22]  M. Takano,et al.  H+ gradient-dependent transport of aminocephalosporins in rat intestinal brush-border membrane vesicles. Role of dipeptide transport system. , 1986, Biochemical pharmacology.

[23]  T. Hoshi Proton-coupled transport of organic solutes in animal cell membranes and its relation to Na+ transport. , 1985, The Japanese journal of physiology.

[24]  N. Takuwa,et al.  Effect of hydrogen ion-gradient on carrier-mediated transport of glycylglycine across brush border membrane vesicles from rabbit small intestine. , 1985, The Japanese journal of physiology.

[25]  V. Ganapathy,et al.  Role of pH gradient and membrane potential in dipeptide transport in intestinal and renal brush-border membrane vesicles from the rabbit. Studies with L-carnosine and glycyl-L-proline. , 1983, The Journal of biological chemistry.

[26]  M. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.