Meta‐analysis: coeliac disease and the risk of all‐cause mortality, any malignancy and lymphoid malignancy

Coeliac disease has been associated with an increased risk of mortality and malignancy. However, the strength of this association is conflicting among different studies.

[1]  J. Ludvigsson,et al.  Coeliac disease characteristics, compliance to a gluten free diet and risk of lymphoma by subtype. , 2011, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[2]  K. Khaw,et al.  No difference in mortality in undetected coeliac disease compared with the general population: a UK cohort study , 2011, Alimentary pharmacology & therapeutics.

[3]  T. Lightfoot,et al.  Non‐Hodgkin lymphoma and autoimmunity: Does gender matter? , 2011, International journal of cancer.

[4]  F. Granath,et al.  Risk of lymphoproliferative malignancy in relation to small intestinal histopathology among patients with celiac disease. , 2011, Journal of the National Cancer Institute.

[5]  Waleed Brinjikji,et al.  Morbidity and mortality among older individuals with undiagnosed celiac disease. , 2010, Gastroenterology.

[6]  Tsung-Teh Wu,et al.  Mucosal Recovery and Mortality in Adults With Celiac Disease After Treatment With a Gluten-Free Diet , 2010, The American Journal of Gastroenterology.

[7]  F. Granath,et al.  Small-intestinal histopathology and mortality risk in celiac disease. , 2009, JAMA.

[8]  S. Berndt,et al.  Population‐based study of autoimmune conditions and the risk of specific lymphoid malignancies , 2009, International journal of cancer.

[9]  Robert A Kyle,et al.  Increased prevalence and mortality in undiagnosed celiac disease. , 2009, Gastroenterology.

[10]  A. Reunanen,et al.  Prognosis of unrecognized coeliac disease as regards mortality: A population-based cohort study , 2009, Annals of medicine.

[11]  A. Reunanen,et al.  Malignancies in cases with screening-identified evidence of coeliac disease: a long-term population-based cohort study , 2008, Gut.

[12]  L. Brown,et al.  Risk of multiple myeloma and monoclonal gammopathy of undetermined significance among white and black male United States veterans with prior autoimmune, infectious, inflammatory, and allergic disorders. , 2008, Blood.

[13]  M. Goldacre,et al.  Cancer in patients with ulcerative colitis, Crohn's disease and coeliac disease: record linkage study , 2008, European journal of gastroenterology & hepatology.

[14]  U. Volta,et al.  Effect of a Gluten-free Diet on the Risk of Enteropathy-associated T-cell Lymphoma in Celiac Disease , 2008, Digestive Diseases and Sciences.

[15]  J. Askling,et al.  Malignant Lymphomas in Autoimmunity and Inflammation: A Review of Risks, Risk Factors, and Lymphoma Characteristics , 2006, Cancer Epidemiology Biomarkers & Prevention.

[16]  R. Hubbard,et al.  Is an internal comparison better than using national data when estimating mortality in longitudinal studies? , 2006, Journal of Epidemiology and Community Health.

[17]  K. Kaukinen,et al.  Malignancies and mortality in patients with coeliac disease and dermatitis herpetiformis: 30-year population-based study. , 2006, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[18]  H. Wichmann,et al.  Mortality Excess in Individuals with Elevated IgA Anti-Transglutaminase Antibodies: The KORA/MONICA Augsburg Cohort Study 1989–1998 , 2006, European Journal of Epidemiology.

[19]  W. Caspary,et al.  Celiac disease , 2006, Orphanet journal of rare diseases.

[20]  R. Brand,et al.  European multi-centre study on coeliac disease and non-Hodgkin lymphoma , 2006, European journal of gastroenterology & hepatology.

[21]  H. Adami,et al.  Autoimmune and chronic inflammatory disorders and risk of non-Hodgkin lymphoma by subtype. , 2006, Journal of the National Cancer Institute.

[22]  G. Holmes,et al.  Risk of malignancy in diagnosed coeliac disease: a 24-year prospective, population-based, cohort study. , 2004, Alimentary pharmacology & therapeutics.

[23]  R. Hubbard,et al.  Malignancy and mortality in people with coeliac disease: population based cohort study , 2004, BMJ : British Medical Journal.

[24]  S. Sanjosé,et al.  Celiac Disease and Lymphoma Risk: A Multicentric Case–Control Study in Spain , 2004, Digestive Diseases and Sciences.

[25]  D. Altman,et al.  Measuring inconsistency in meta-analyses , 2003, BMJ : British Medical Journal.

[26]  A. Neugut,et al.  Risk of malignancy in patients with celiac disease. , 2003, The American journal of medicine.

[27]  U. Peters,et al.  Causes of death in patients with celiac disease in a population-based Swedish cohort. , 2003, Archives of internal medicine.

[28]  J. Murray,et al.  Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. , 2003, Archives of internal medicine.

[29]  J. Askling,et al.  Cancer incidence in a population-based cohort of individuals hospitalized with celiac disease or dermatitis herpetiformis. , 2002, Gastroenterology.

[30]  G. Corrao,et al.  Risk of non-Hodgkin lymphoma in celiac disease. , 2002, JAMA.

[31]  G. Corrao,et al.  For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group , 2022 .

[32]  I. Olkin,et al.  Meta-analysis of observational studies in epidemiology - A proposal for reporting , 2000 .

[33]  A. Sonnenberg,et al.  Celiac Sprue Among US Military Veterans (Associated Disorders and Clinical Manifestations) , 1999, Digestive Diseases and Sciences.

[34]  G. Smith,et al.  Bias in meta-analysis detected by a simple, graphical test , 1997, BMJ.

[35]  G. Holmes,et al.  Malignancy in coeliac disease--effect of a gluten free diet. , 1989, Gut.

[36]  N. Laird,et al.  Meta-analysis in clinical trials. , 1986, Controlled clinical trials.

[37]  R. Orwin A fail-safe N for effect size in meta-analysis. , 1983 .

[38]  J. Stockman Small-Intestinal Histopathology and Mortality Risk in Celiac Disease , 2011 .

[39]  M. Björkholm,et al.  Increased risk for non-Hodgkin lymphoma in individuals with celiac disease and a potential familial association. , 2009, Gastroenterology.

[40]  A. Gavin,et al.  Malignancy and mortality in a population-based cohort of patients with coeliac disease or 'gluten sensitivity' , 2006 .